| Literature DB >> 31382982 |
Arnaud Cassignol1, Julien Marmin2, Jean Cotte3, Mickael Cardinale3, Julien Bordes3, Vanessa Pauly4, François Kerbaul5,6, Didier Demory7, Eric Meaudre3.
Abstract
BACKGROUND: In France, the pre-hospital field triage of trauma patients is currently based on the Vittel criteria algorithm. This algorithm was originally created in 2002 before the stratification of trauma centers and, at the national level, has not been revised since. This could be responsible for the overtriage of trauma patients in Level I Trauma Centers. The principal aim of this study was to evaluate the correlation between each Vittel field triage criterion and trauma patients' Injury Severity Score.Entities:
Keywords: Algorithm; Field triage; ISS; Intensive care unit; Mortality; Vittel criteria
Mesh:
Year: 2019 PMID: 31382982 PMCID: PMC6683531 DOI: 10.1186/s13049-019-0652-0
Source DB: PubMed Journal: Scand J Trauma Resusc Emerg Med ISSN: 1757-7241 Impact factor: 2.953
Fig. 1Vittel Criteria Algorithm for French field triage. GCS: Glasgow Coma Scale; SBP: Systolic Blood Pressure
Fig. 2Study population flowchart. ISS: Injury Severity Score, D: Day, ICU: Intensive Care Unit
Study population characteristics (n = 1151 patients)
| Characteristic | Value |
|---|---|
| Sex: Male, | 887 (77) |
| Age: mean (SD) | 43 (±19) |
| Mechanism of injury | |
| Blunt, | 1063 (92) |
| Penetrating, | 88 (8) |
| Type of trauma | |
| Car crash, | 263 (23) |
| Motorcycle, | 457 (40) |
| Pedestrian, | 74 (6) |
| Fall, | 228 (20) |
| Gunshot, | 48 (4) |
| Stab wound, | 34 (3) |
| Other, | 47 (4) |
| Pre-hospital physiological variables: median (IQR) | |
| Glasgow coma scale | 15 (13–15) |
| Heart rate, beats/min | 86 (75–100) |
| Systolic arterial blood pressure, mm Hg | 120 (108–137) |
| Peripheral oxygen saturation, % | 99 (97–100) |
| Pre-hospital resuscitation | |
| Mechanical Ventilation, | 197 (17) |
| Catecholamine administration, | 106 (9) |
| Total fluid loading, mL: median (IQR) | 250 (0–500) |
| MGAP score: median (IQR) | 27 (22–28) |
| MGAP category, | |
| 3–17 a | 133 (12) |
| 18–22 b | 201 (18) |
| 23–29 c | 817 (71) |
| ISS: median (IQR) | 13 (5–22) |
| ISS ≥ 15, | 524 (46) |
| Field triage criterion categories, | |
| Physiological variables | 420 (15) |
| Kinetic elements | 1328 (48) |
| Physical injuries | 383 (14) |
| Pre-hospital resuscitation | 373 (13.5) |
| Special considerations | 260 (9.5) |
| ICU admission during the hospital stay, | 660 (57) |
| In-hospital mortality within 30 days, | 91 (8) |
MGAP score: Mechanism, Glasgow coma scale, Age, systolic blood Pressure
aHigh risk of mortality; bintermediate risk of mortality; clow risk of mortality
ISS Injury Severity Score, ICU Intensive Care Unit
Association between each field triage criterion and risk of an ISS > 15, mortality, or admission to intensive care, respectively, in univariate analysis
| Field triage criteria | Evaluation criterion, OR (95% CI) | |||||
|---|---|---|---|---|---|---|
| ISS > 15 | 30-day mortality | Admission to ICU | ||||
| GCS score < 13 | 252 | 7.9 (5.6–11.2) | 17.2 (10.2–29) | 8.5 (5.6–12.9) | ||
| SBP < 90 mmHg | 105 | 4.1 (2.6–6.5) | 3 (1.7–5.2) | 4.3 (2.5–7.3) | ||
| Oxygen saturation < 90% | 63 | 4.5 (2.5–8.3) | 9.4 (5.3–16.5) | 3.3 (1.8–6.3) | ||
| Ejection from vehicle | 112 | 0.9 (0.6–1.3) | 0.9 (0.4–1.9) | 1.4 (0.9–2.1) | ||
| Death of another passenger | 31 | 1.5 (0.7–3) | 0.8 (0.2–3.4) | 3.2 (1.3–7.8) | ||
| Fall > 6 m | 228 | 1.3 (1–1.8) | 1.5 (0.9–2.5) | 1.1 (0.8–1.4) | ||
| Victim thrown or run over | 253 | 1.1 (0.8–1.4) | 1.1 (0.7–1.9) | 1.4 (1.02–1.8) | ||
| Global assessment (speed or vehicle deformation) | 701 | 0.9 (0.7–1.1) | 0.6 (0.4–0.8) | 1 (0.8–1.2) | ||
| Blast | 3 | 0.6 (0.1–6.6) | NC | 0.4 (0.03–4.1) | ||
| Penetrating trauma | 88 | 1.1 (0.7–1.6) | 3.2 (1.8–5.7) | 1 (0.7–1.6) | ||
| Flail chest | 48 | 9 (3.8–21.4) | 2.1 (0.9–4.8) | 3.4 (1.6–7) | ||
| Severe burn | 4 | 1.2 (0.2–8.5) | 3.9 (0.4–38) | NC | ||
| Pelvis fracture | 72 | 1.6 (1.01–2.6) | 0.9 (0.3–2.2) | 2 (1.2–3.4) | ||
| Spinal cord injury | 137 | 2.5 (1.7–3.6) | 3 (1.8–5) | 2.7 (1.8–4.1) | ||
| Amputation | 17 | 2.9 (1.02–8.3) | 2.6 (0.7–9) | 3.5 (1.01–12.3) | ||
| Acute limb ischemia | 17 | 1.7 (0.7–4.6) | 0.7 (0.1–5.5) | 1.4 (0.5–3.7) | ||
| Mechanical ventilation | 197 | 8.9 (6–13.4) | 13.8 (8.6–22.1) | 19.1 (10–36.5) | ||
| Total fluid resuscitation > 1000 mL | 70 | 8 (4–15.8) | 2.9 (1.5–5.6) | 5.5 (2.7–11.1) | ||
| Catecholamine administration | 106 | 10.2 (5.7–18.5) | 10.4 (6.4–16.9) | 14.5 (6.3–33.4) | ||
| Age > 65 years | 192 | 2 (1.5–2.8) | 4.7 (3–7.3) | 1.5 (1.1–2.1) | ||
| Heart failure | 29 | 1.3 (0.6–2.7) | 2.5 (0.9–6.7) | 1.4 (0.7–3.1) | ||
| Respiratory failure | 4 | 1.2 (0.2–8.5) | NC | 0.7 (0.1–5.3) | ||
| Pregnancy | 4 | 1.2 (0.2–8.5) | NC | 0.3 (0.03–2.4) | ||
| Anticoagulant use or bleeding disorders | 31 | 1.3 (0.6–2.6) | 3.6 (1.5–8.6) | 1.4 (0.7–2.9) | ||
GCS Glasgow Coma Scale, SBP Systolic Blood Pressure, ISS Injury Severity Score, OR Odds Ratio, NC Not Calculable
aN = total number of triage criteria recorded within the study population (n = 1151)
Association between each field triage criterion and risk of an ISS > 15, mortality, or admission to intensive care, respectively, in multivariate analysis
| Field triage criteria | Evaluation criterion, OR (95% CI) | ||||
|---|---|---|---|---|---|
| ISS > 15 | 30-day mortality | Admission to ICU | |||
| GCS score < 13 | 4.2 (2.7–6.6) | 7.6 (3.6–16.2) | 3.4 (2.1–5.5) | ||
| SBP < 90 mmHg | 2.3 (1.3–3.9) | NS | 2.3 (1.3–4.3) | ||
| Oxygen saturation < 90% | NS | 5.6 (2.8–11.6) | NS | ||
| Flail chest | 8 (3.2–19.9) | NS | 2.8 (1.3–6.1) | ||
| Pelvis fracture | NS | NS | 2.2 (1.3–3.9) | ||
| Amputation | 3.4 (1.1–10.4) | NS | NS | ||
| Spinal cord injury | 1.9 (1.2–2.9) | NS | 2.1 (1.3–3.3) | ||
| Penetrating trauma | NS | 3.2 (1.5–7.1) | NS | ||
| Mechanical ventilation | 2.2 (1.3–3.8) | 4.1 (1.8–9) | 5.9 (2.8–12.4) | ||
| Total fluid loading > 1000 mL | 4 (1.9–8.5) | NS | NS | ||
| Catecholamine administration | 2 (1.01–4.1) | 2.3 (1.2–4.4) | 2.8 (1.1–7.1) | ||
| Age > 65 years | 2 (1.4–2.8) | 7.6 (4–14.4) | 1.5 (1.02–2.1) | ||
| Anticoagulant use or bleeding disorders | NS | 3.8 (1.1–10.9) | NS | ||
GCS Glasgow Coma Scale, SBP Systolic Blood Pressure, ISS Injury Severity Score, OR Odds Ratio, NS Not Significant
Performance of each category of the Vittel Criteria Algorithm (VCA) in predicting the risk of an ISS > 15, mortality within 30 days, or admission to Intensive Care Unit
| VCA Category | Predictive performance for an ISS > 15 | |||||||
|---|---|---|---|---|---|---|---|---|
| Se % | Sp % | PPV % | NPV % | PLR | NLR | Youden index | ||
| Step 1: Physiological variables | 420 | 50 | 87 | 77 | 68 | 3,9 | 0.57 | 0.37 |
| Step 2: Kinetic elements | 1328 | 86 | 13 | 45 | 52 | 0.99 | 1.09 | −0.01 |
| Step 3: Physical injuries | 383 | 41 | 77 | 60 | 61 | 1.77 | 0.77 | 0.18 |
| Step 4: Pre-hospital resuscitation | 373 | 41 | 94 | 84 | 65 | 6.19 | 0.68 | 0.34 |
| Step 5: Special considerations | 260 | 23 | 86 | 58 | 57 | 1.27 | 0.85 | 0.09 |
| VCA Category | Predictive performance for 30-day mortality | |||||||
| Se % | Sp % | VPP % | VPN % | PLR | NLR | Youden index | ||
| Step 1: Physiological variables | 420 | 89 | 75 | 24 | 99 | 3.57 | 0.15 | 0.64 |
| Step 2: Kinetic elements | 1328 | 77 | 13 | 7 | 86 | 0.88 | 1.85 | −0.11 |
| Step 3: Physical injuries | 383 | 54 | 71 | 14 | 95 | 1.87 | 0.65 | 0.25 |
| Step 4: Pre-hospital resuscitation | 373 | 73 | 82 | 26 | 97 | 4.11 | 0.33 | 0.55 |
| Step 5: Special considerations | 260 | 45 | 84 | 20 | 95 | 2.8 | 0.7 | 0.29 |
| VCA Category | Predictive performance for admission to ICU | |||||||
| Se % | Sp % | VPP % | VPN % | PLR | NLR | Youden index | ||
| Step 1: Physiological variables | 420 | 45 | 90 | 86 | 55 | 4.49 | 0.61 | 0.35 |
| Step 2: Kinetic elements | 1328 | 86 | 12 | 57 | 39 | 0.98 | 1.19 | −0.02 |
| Step 3: Physical injuries | 383 | 38 | 78 | 70 | 48 | 1.75 | 0.79 | 0.16 |
| Step 4: Pre-hospital resuscitation | 373 | 36 | 97 | 93 | 53 | 10.3 | 0.7 | 0.32 |
| Step 5: Special considerations | 260 | 20 | 85 | 64 | 44 | 1.3 | 0.9 | 0.05 |
Se Sensibility, Sp Specificity, PPV Positive Predictive Value, NPV Negative Predictive Value, PLR Positive Likelihood Ratio, NLR Negative Likelihood Ratio
aN = total number of triage criteria within the study population (n = 1151)
Fig. 3ROC curves illustrating the predictive performance of each of the 3 algorithms concerning an ISS > 15. (a) French Vittel Criteria Algorithm (VCA) reference (b) First alternative algorithm, a 4-step algorithm: VCA without kinetic elements (2nd category) (c) Second alternative algorithm, a 3-step algorithm: VCA without kinetic elements (2nd category) or special considerations (5th category)
Comparison between the predictive performance of the Vittel Criteria Algorithm (VCA) for an ISS > 15 and of our two alternative algorithms
| Pre-hospital field triage algorithms | AUC difference | 95% CI | |
|---|---|---|---|
| VCA vs. 4-step algorithm | 0.012 | −0.004 – 0.028 | 0.15 |
| VCA vs. 3-step algorithm | 0.008 | −0.012 – 0.029 | 0.43 |
| 4-step algorithm vs. 3-step algorithm | 0.004 | −0.009 – 0.016 | 0.59 |
AUC Area Under Curve
VCA Vittel Criteria Algorithm