Literature DB >> 31382143

TGF-β signaling in cell fate control and cancer.

Yi Yu1, Xin-Hua Feng2.   

Abstract

Members of the transforming growth factor-β (TGF-β) family regulate cell fate decisions during early embryonic development and tissue homeostasis in the adult. Deregulation of TGF-β family signaling contributes to developmental anomalies, fibrotic disorders, tumorigenesis and immune diseases. TGF-β exerts a wide spectrum of cellular functions by activating canonical (SMAD-dependent) or non-canonical (SMAD-independent) pathways in a cell type-specific and context-dependent manner. Here, we focus on recent advances in the understanding of the mechanisms and functions of SMAD and non-SMAD pathways in physiology and pathology.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2019        PMID： 31382143     DOI： 10.1016/j.ceb.2019.07.007

Source DB:  PubMed          Journal:  Curr Opin Cell Biol        ISSN： 0955-0674            Impact factor:   8.382


  24 in total

Review 1.  Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression.

Authors:  Halima Ouadid-Ahidouch; Hamid Morjani; Julie Schnipper; Alban Girault; Ahmed Ahidouch
Journal:  Rev Physiol Biochem Pharmacol       Date:  2021       Impact factor: 5.545

2.  TGF-β Signaling Pathway-Based Model to Predict the Subtype and Prognosis of Head and Neck Squamous Cell Carcinoma.

Authors:  Lian Zheng; Zhenjie Guan; Miaomiao Xue
Journal:  Front Genet       Date:  2022-05-02       Impact factor: 4.772

3.  Characterization of the development of the mouse cochlear epithelium at the single cell level.

Authors:  Likhitha Kolla; Michael C Kelly; Zoe F Mann; Alejandro Anaya-Rocha; Kathryn Ellis; Abigail Lemons; Adam T Palermo; Kathy S So; Joseph C Mays; Joshua Orvis; Joseph C Burns; Ronna Hertzano; Elizabeth C Driver; Matthew W Kelley
Journal:  Nat Commun       Date:  2020-05-13       Impact factor: 14.919

4.  Circular RNA cESRP1 sensitises small cell lung cancer cells to chemotherapy by sponging miR-93-5p to inhibit TGF-β signalling.

Authors:  Weimei Huang; Yunchu Yang; Jingfang Wu; Yuchun Niu; Yao Yao; Jian Zhang; Xiaoxian Huang; Shumei Liang; Rui Chen; Size Chen; Linlang Guo
Journal:  Cell Death Differ       Date:  2019-11-14       Impact factor: 15.828

Review 5.  Cadherin Signaling in Cancer: Its Functions and Role as a Therapeutic Target.

Authors:  Weina Yu; Li Yang; Ting Li; Yi Zhang
Journal:  Front Oncol       Date:  2019-10-04       Impact factor: 6.244

Review 6.  Trash Talk: Mammalian Proteasome Regulation at the Transcriptional Level.

Authors:  Hatem Elif Kamber Kaya; Senthil K Radhakrishnan
Journal:  Trends Genet       Date:  2020-09-25       Impact factor: 11.639

7.  Transforming Growth Factor-β Signaling Regulates Tooth Root Dentinogenesis by Cooperation With Wnt Signaling.

Authors:  Ran Zhang; Jingting Lin; Yang Liu; Shurong Yang; Qi He; Liang Zhu; Xiao Yang; Guan Yang
Journal:  Front Cell Dev Biol       Date:  2021-06-29

Review 8.  LTBP4 in Health and Disease.

Authors:  Chi-Ting Su; Zsolt Urban
Journal:  Genes (Basel)       Date:  2021-05-23       Impact factor: 4.096

Review 9.  From the Performance to the Essence: The Biological Mechanisms of How Tantalum Contributes to Osteogenesis.

Authors:  Hu Qian; Ting Lei; Zhimin Ye; Yihe Hu; Pengfei Lei
Journal:  Biomed Res Int       Date:  2020-07-27       Impact factor: 3.411

10.  The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription.

Authors:  Xiao Li; Mengmeng Liu; Xingjie Ren; Nicolas Loncle; Qun Wang; Rajitha-Udakara-Sampath Hemba-Waduge; Stephen H Yu; Muriel Boube; Henri-Marc G Bourbon; Jian-Quan Ni; Jun-Yuan Ji
Journal:  PLoS Genet       Date:  2020-05-28       Impact factor: 5.917
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