Literature DB >> 31373815

Bioactive Polyketide Derivatives from the Mangrove-Derived Fungus Daldinia eschscholtzii HJ004.

Hai-Xia Liao1,2,3,4, Cai-Juan Zheng1,2, Guo-Lei Huang1,2, Rong-Qing Mei1,2, Xu-Hua Nong1,2, Tai-Ming Shao1,2,4, Guang-Ying Chen1,2, Chang-Yun Wang3.   

Abstract

Five new tetralones, daldiniones A-E (1-5), three new chromones, 7-hydroxy-5-methoxy-2,3-dimethylchromone (9), 5-methoxy-2-propylchromone (10), and 7-ethyl-8-hydroxy-6-methoxy-2,3-dimethylchromone (11), and two new lactones, helicascolides D and E (16 and 17), together with nine known metabolites (6-8, 12-15, and 18-19) were isolated from the mangrove-derived fungus Daldinia eschscholtzii HJ004. The structures and absolute configurations of the new compounds were determined by analyzing MS and NMR data and utilizing GIAO based 13C NMR chemical shift calculations and quantum chemical electronic circular dichroism (ECD) calculations. Compounds 9, 13, and 18 showed inhibitory activities against α-glucosidase with IC50 values of 13, 15, and 16 μM, respectively.

Entities:  

Year:  2019        PMID： 31373815     DOI： 10.1021/acs.jnatprod.9b00241

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Diversified Polyketides With Anti-inflammatory Activities From Mangrove Endophytic Fungus Daldinia eschscholtzii KBJYZ-1.

Authors:  Guisheng Wang; Zhenhua Yin; Senye Wang; Yilin Yuan; Yan Chen; Wenyi Kang
Journal:  Front Microbiol       Date:  2022-05-10       Impact factor: 6.064

2.  Talaromarins A-F: Six New Isocoumarins from Mangrove-Derived Fungus Talaromyces flavus TGGP35.

Authors:  Jin Cai; Xiao-Chen Zhu; Wei-Nv Zeng; Bin Wang; You-Ping Luo; Jing Liu; Min-Jing Chen; Gao-Yu Li; Guo-Lei Huang; Guang-Ying Chen; Jing Xu; Cai-Juan Zheng
Journal:  Mar Drugs       Date:  2022-05-27       Impact factor: 6.085

3.  New Drimane Sesquiterpenes and Polyketides from Marine-Derived Fungus Penicillium sp. TW58-16 and Their Anti-Inflammatory and α-Glucosidase Inhibitory Effects.

Authors:  Xiaoshuang Gou; Danmei Tian; Jihua Wei; Yihan Ma; Yixue Zhang; Mei Chen; Wenjuan Ding; Bin Wu; Jinshan Tang
Journal:  Mar Drugs       Date:  2021-07-26       Impact factor: 5.118

4.  Daldiniaeschsone A, a Rare Tricyclic Polyketide Having a Chromone Unit Fused to a δ-Lactone and Its Symmetrical Biphenyl Dimer, Daldiniaeschsone B, from an Endophytic Fungus Daldinia eschscholtzii SDBR-CMUNKC745.

Authors:  Natnicha Wutthiwong; Virayu Suthiphasilp; Aknarin Pintatum; Nakarin Suwannarach; Jaturong Kumla; Saisamorn Lumyong; Tharakorn Maneerat; Rawiwan Charoensup; Sarot Cheenpracha; Thunwadee Limtharakul; Stephen G Pyne; Surat Laphookhieo
Journal:  J Fungi (Basel)       Date:  2021-05-02

5.  Bioactive Secondary Metabolites from the Culture of the Mangrove-Derived Fungus Daldinia eschscholtzii HJ004.

Authors:  Hai-Xia Liao; Tai-Ming Shao; Rong-Qing Mei; Guo-Lei Huang; Xue-Ming Zhou; Cai-Juan Zheng; Chang-Yun Wang
Journal:  Mar Drugs       Date:  2019-12-17       Impact factor: 5.118

Review 6.  Recent progress in biodiversity research on the Xylariales and their secondary metabolism.

Authors:  Kevin Becker; Marc Stadler
Journal:  J Antibiot (Tokyo)       Date:  2020-10-23       Impact factor: 2.649
  6 in total

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