Literature DB >> 3137173

Measurement of Pseudomonas aeruginosa phenazine pigments in sputum and assessment of their contribution to sputum sol toxicity for respiratory epithelium.

R Wilson1, D A Sykes, D Watson, A Rutman, G W Taylor, P J Cole.   

Abstract

The phenazine pigments pyocyanin and 1-hydroxyphenazine were resolved by high-pressure liquid chromatography from the sputum sol phase from 9 of 13 patients with cystic fibrosis or bronchiectasis colonized by Pseudomonas aeruginosa. The concentrations measured were each sufficient to inhibit ciliary beating in vitro and contributed a significant proportion of sol phase toxicity for respiratory epithelium.

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Year:  1988        PMID： 3137173      PMCID： PMC259599          DOI： 10.1128/iai.56.9.2515-2517.1988

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  12 in total

1.  The effect of pyocyanin on human skin cells and leucocytes.

Authors:  C N CRUICKSHANK; E J LOWBURY
Journal:  Br J Exp Pathol       Date:  1953-12

2.  Purification and structural analysis of pyocyanin and 1-hydroxyphenazine.

Authors:  D Watson; J MacDermot; R Wilson; P J Cole; G W Taylor
Journal:  Eur J Biochem       Date:  1986-09-01

3.  Pyocyanin and 1-hydroxyphenazine produced by Pseudomonas aeruginosa inhibit the beating of human respiratory cilia in vitro.

Authors:  R Wilson; T Pitt; G Taylor; D Watson; J MacDermot; D Sykes; D Roberts; P Cole
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

4.  Non-invasive sampling of nasal cilia for measurement of beat frequency and study of ultrastructure.

Authors:  J Rutland; P J Cole
Journal:  Lancet       Date:  1980-09-13       Impact factor: 79.321

5.  Characterisation of the Pseudomonas aeruginosa factor that inhibits mouse-liver mitochondrial respiration.

Authors:  A V Armstrong; D E Stewart-Tull; J S Roberts
Journal:  J Med Microbiol       Date:  1971-05       Impact factor: 2.472

6.  Reduction of ciliary beat frequency in vitro by sputum from patients with bronchiectasis: a serine proteinase effect.

Authors:  L A Smallman; S L Hill; R A Stockley
Journal:  Thorax       Date:  1984-09       Impact factor: 9.139

7.  Granulocyte neutral proteases and Pseudomonas elastase as possible causes of airway damage in patients with cystic fibrosis.

Authors:  S Suter; U B Schaad; L Roux; U E Nydegger; F A Waldvogel
Journal:  J Infect Dis       Date:  1984-04       Impact factor: 5.226

8.  Role of pyocyanin in the acquisition of iron from transferrin.

Authors:  C D Cox
Journal:  Infect Immun       Date:  1986-04       Impact factor: 3.441

9.  Studies on the mechanism of T cell inhibition by the Pseudomonas aeruginosa phenazine pigment pyocyanine.

Authors:  J Nutman; M Berger; P A Chase; D G Dearborn; K M Miller; R L Waller; R U Sorensen
Journal:  J Immunol       Date:  1987-05-15       Impact factor: 5.422

10.  Effect of human leukocyte enzymes on tracheal mucosa and its mucociliary activity.

Authors:  H Tegner; K Ohlsson; N G Toremalm; C von Mecklenburg
Journal:  Rhinology       Date:  1979-09       Impact factor: 3.681
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  131 in total

1.  Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin.

Authors:  R J Gryglewski; A Zembowicz; D Salvemini; G W Taylor; J R Vane
Journal:  Br J Pharmacol       Date:  1992-08       Impact factor: 8.739

Review 2.  The multiple signaling systems regulating virulence in Pseudomonas aeruginosa.

Authors:  Pol Nadal Jimenez; Gudrun Koch; Jessica A Thompson; Karina B Xavier; Robbert H Cool; Wim J Quax
Journal:  Microbiol Mol Biol Rev       Date:  2012-03       Impact factor: 11.056

3.  The purification, crystallization and preliminary structural characterization of PhzM, a phenazine-modifying methyltransferase from Pseudomonas aeruginosa.

Authors:  Neelakshi Gohain; Linda S Thomashow; Dmitri V Mavrodi; Wulf Blankenfeldt
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-08-11

4.  The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa.

Authors:  Neelakshi Gohain; Linda S Thomashow; Dmitri V Mavrodi; Wulf Blankenfeldt
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2006-09-30

5.  Calcium-induced virulence factors associated with the extracellular matrix of mucoid Pseudomonas aeruginosa biofilms.

Authors:  S Sarkisova; M A Patrauchan; D Berglund; D E Nivens; M J Franklin
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

6.  Production of leukotriene B4 and 5-hydroxyeicosatetraenoic acid by human neutrophils is inhibited by Pseudomonas aeruginosa phenazine derivatives.

Authors:  M Muller; T C Sorrell
Journal:  Infect Immun       Date:  1991-09       Impact factor: 3.441

Review 7.  Anti-virulence strategies to combat bacteria-mediated disease.

Authors:  David A Rasko; Vanessa Sperandio
Journal:  Nat Rev Drug Discov       Date:  2010-01-18       Impact factor: 84.694

8.  Bacterial defenses against a natural antibiotic promote collateral resilience to clinical antibiotics.

Authors:  Lucas A Meirelles; Elena K Perry; Megan Bergkessel; Dianne K Newman
Journal:  PLoS Biol       Date:  2021-03-10       Impact factor: 8.029

9.  Pseudomonas pyocyanin increases interleukin-8 expression by human airway epithelial cells.

Authors:  G M Denning; L A Wollenweber; M A Railsback; C D Cox; L L Stoll; B E Britigan
Journal:  Infect Immun       Date:  1998-12       Impact factor: 3.441

10.  Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.

Authors:  Benjamin R Lundgren; William Thornton; Mark H Dornan; Luis Roberto Villegas-Peñaranda; Christopher N Boddy; Christopher T Nomura
Journal:  J Bacteriol       Date:  2013-03-01       Impact factor: 3.490
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