| Literature DB >> 3137019 |
G Braathen1, K Theorell, A Persson, A Rane.
Abstract
Seven children with absence epilepsy were treated with valproate (VPA). All but one child became free of absence seizures during VPA monotherapy. EEG was recorded for 24 h before start of VPA treatment and repeatedly during treatment. Correlation between plasma VPA concentration and reduction of the number of epileptic discharges was significant. Plasma concentration of 440-660 microM VPA was needed to achieve at least 50% reduction of seizure activity.Entities:
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Year: 1988 PMID： 3137019 DOI： 10.1111/j.1528-1157.1988.tb03759.x
Source DB: PubMed Journal: Epilepsia ISSN： 0013-9580 Impact factor: 5.864