Literature DB >> 31370013

Intracranial infections: lessons learned from 52 surgically treated cases.

Cahit Kural1, Sahin Kırmızıgoz1, Mehmet Can Ezgu1, Orhan Bedir2, Murat Kutlay1, Yusuf Izci1.   

Abstract

OBJECTIVE: Intracranial infections are serious and life-threatening health problems. They may present as subdural empyemas or intracerebral abscesses. Surgical drainage and subsequent antibiotic treatment is the main technique for a satisfactory clinical outcome. The aims of this study were to present a 10-year intracranial infection series and discuss the surgical characteristics in the light of literature.
METHODS: Fifty-two patients with intracranial infection underwent surgical treatment between 2008 and 2018. Eleven patients were female and 41 patients were male. The mean age was 40.46 years (range 10-75 years). Eighteen patients had intracerebral abscesses, and 34 had subdural empyemas. All patients underwent surgical treatment as well as an antibiotic regimen.
RESULTS: No etiological agent was isolated in 29 (56%) cases. Bacterial agents were detected in 20 cases, while fungi were observed in 3 cases. Staphylococci species were the most common agents and were isolated in 8 (15%) cases. Endoscopic aspiration was performed in 3 cases, while surgical drainage and capsule resection via craniotomy was performed in 49 cases. An associated intracranial tumor was diagnosed in 2 patients with brain abscesses. Four (8%) patients died despite surgical and medical treatments.
CONCLUSIONS: Surgical treatment via craniotomy is an older method, but it is still the best to treat the intracranial infections not only for decompression of the brain but also to attain an accurate diagnosis. The abscess wall should always be histologically examined after surgery to rule out any intracranial tumor.

Entities:  

Keywords:  abscess; empyema; infection; surgery

Year:  2019        PMID: 31370013     DOI: 10.3171/2019.5.FOCUS19238

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  3 in total

1.  Risk factors for intracranial infection after craniotomy: A case-control study.

Authors:  Li-Yi Wang; Xu-Hua Cao; Li-Ke Shi; Zhi-Zhao Ma; Yue Wang; Yan Liu
Journal:  Brain Behav       Date:  2020-05-18       Impact factor: 2.708

Review 2.  Immunopathogenesis of Craniotomy Infection and Niche-Specific Immune Responses to Biofilm.

Authors:  Sharon Db de Morais; Gunjan Kak; Joseph P Menousek; Tammy Kielian
Journal:  Front Immunol       Date:  2021-02-23       Impact factor: 7.561

Review 3.  Differential Diagnosis and Hospital Emergency Management for Fastlane Treatment of Central Nervous System Infection Under the COVID-19 Epidemic in Changsha, China.

Authors:  Haojun Yang; Yunfang Chi; Zhuohui Chen; Yishu Fan; Haiyue Wu; Xinhang Hu; Tong Wu; Bo Xiao; Mengqi Zhang
Journal:  Front Neurol       Date:  2020-10-20       Impact factor: 4.003

  3 in total

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