Literature DB >> 31367729

Frailty Could Predict Death in Older Adults after Admissionat Emergency Department? A 6-month Prospective Study from a Middle-Income Country.

I Aprahamian1, G V Aricó de Almeida, C F de Vasconcellos Romanin, T Gomes Caldas, N T Antunes Yoshitake, L Bataglini, S Mori Lin, A Alves Pereira, L Nara Alegrini Longhi, R L Mamoni, J E Martinelli.   

Abstract

BACKGROUND: The number of older adults attending emergency department (ED) is increasing all over the world. Usually, those patients are potentially more complex due to their greater number of comorbidities, cognitive disorders, and functional or physical disabilities. Frailty is a vulnerable state that could predict adverse outcomes of those patients. There are very few studies that addressed this topic in the ED, and none of them used a simple instrument for frailty assessment.
OBJECTIVES: The primary outcome was to evaluate the association between frailty identified through the FRAIL questionnaire at baseline and death after a 6-month follow-up period after hospital discharge from the ED. Secondary outcomes were readmission to the ED and disability after 6 months.
METHODS: A 6-month follow-up prospective study (FASES study) was conducted at a university-based trauma-center ED in Jundiaí, southwestern of Brazil. A total of 316 older adults aged 60 or older were randomly included based on a lottery of their medical record admission number. Frailty was evaluated through the FRAIL questionnaire. The association between frailty and death was estimated through a binary logistic regression adjusted for age, sex, and cognitive performance.
RESULTS: From the total sample, the mean age was 72.11±8.0 years, and 51.6% were women. Participants presented 2.28±1.4 comorbidities and 25.6% were frail. Mean hospital stay was 5.43±5.6 days. Death occurred in 52 participants, readmission to the emergency in 55, and new disability in 16 after 6 months. Frailty was associated with an odds ratio of 2.18 for death after 6 months (95% CI = 1.10-4.31; p = 0.024). This association lost significance after multivariate analysis taking into account cognitive performance. There was no association between frailty status at baseline and readmission to the ED or disability.
CONCLUSION: The identification of frailty using the FRAIL at admission was not predictive of death after a 6-month period after discharge from the ED. Simple frailty assessment could identify patients at higher risk for death in the follow-up.

Entities:  

Keywords:  Frailty; adverse reactions; emergency; prognosis

Mesh:

Year:  2019        PMID: 31367729     DOI: 10.1007/s12603-019-1207-9

Source DB:  PubMed          Journal:  J Nutr Health Aging        ISSN: 1279-7707            Impact factor:   4.075


  28 in total

1.  Frailty predicts some but not all adverse outcomes in older adults discharged from the emergency department.

Authors:  S Nicole Hastings; Jama L Purser; Kimberly S Johnson; Richard J Sloane; Heather E Whitson
Journal:  J Am Geriatr Soc       Date:  2008-08-04       Impact factor: 5.562

2.  [Reliability of the Brazilian version of the ++abbreviated form of Geriatric Depression Scale (GDS) short form].

Authors:  O P Almeida; S A Almeida
Journal:  Arq Neuropsiquiatr       Date:  1999-06       Impact factor: 1.420

3.  Geriatric emergency medicine: a survey of practicing emergency physicians.

Authors:  R M McNamara; E Rousseau; A B Sanders
Journal:  Ann Emerg Med       Date:  1992-07       Impact factor: 5.721

4.  Rapid emergency department intervention for older people reduces risk of functional decline: results of a multicenter randomized trial.

Authors:  J McCusker; J Verdon; P Tousignant; L P de Courval; N Dendukuri; E Belzile
Journal:  J Am Geriatr Soc       Date:  2001-10       Impact factor: 5.562

5.  Establishing a case-finding and referral system for at-risk older individuals in the emergency department setting: the SIGNET model.

Authors:  L C Mion; R M Palmer; G J Anetzberger; S W Meldon
Journal:  J Am Geriatr Soc       Date:  2001-10       Impact factor: 5.562

6.  A randomized, controlled trial of comprehensive geriatric assessment and multidisciplinary intervention after discharge of elderly from the emergency department--the DEED II study.

Authors:  Gideon A Caplan; Anthony J Williams; Barbra Daly; Ken Abraham
Journal:  J Am Geriatr Soc       Date:  2004-09       Impact factor: 5.562

7.  A brief risk stratification tool to predict functional decline in older adults discharged from emergency departments.

Authors:  Fredric M Hustey; Lorraine C Mion; Jason T Connor; Charles L Emerman; James Campbell; Robert M Palmer
Journal:  J Am Geriatr Soc       Date:  2007-08       Impact factor: 5.562

8.  A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men.

Authors:  Kristine E Ensrud; Susan K Ewing; Peggy M Cawthon; Howard A Fink; Brent C Taylor; Jane A Cauley; Thuy-Tien Dam; Lynn M Marshall; Eric S Orwoll; Steven R Cummings
Journal:  J Am Geriatr Soc       Date:  2009-02-22       Impact factor: 5.562

9.  Clinical characteristics and outcomes of hospitalized older patients with distinct risk profiles for functional decline: a prospective cohort study.

Authors:  Bianca M Buurman; Jita G Hoogerduijn; Elisabeth A van Gemert; Rob J de Haan; Marieke J Schuurmans; Sophia E de Rooij
Journal:  PLoS One       Date:  2012-01-04       Impact factor: 3.240

10.  Validation and comparison of two frailty indexes: The MOBILIZE Boston Study.

Authors:  Dan K Kiely; L Adrienne Cupples; Lewis A Lipsitz
Journal:  J Am Geriatr Soc       Date:  2009-07-21       Impact factor: 5.562

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  3 in total

1.  Geriatric Syndromes and SARS-Cov-2: More than Just Being Old.

Authors:  I Aprahamian; M Cesari
Journal:  J Frailty Aging       Date:  2020

Review 2.  Frailty assessment in emergency medicine using the Clinical Frailty Scale: a scoping review.

Authors:  Christophe Alain Fehlmann; Christian Hans Nickel; Emily Cino; Zinnia Al-Najjar; Nigèle Langlois; Debra Eagles
Journal:  Intern Emerg Med       Date:  2022-07-21       Impact factor: 5.472

3.  Editorial: COVID-19 and Older Adults.

Authors:  J E Morley; B Vellas
Journal:  J Nutr Health Aging       Date:  2020       Impact factor: 4.075

  3 in total

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