Literature DB >> 31367587

Melanoma-Associated Spongiform Scleropathy Adjacent to a Choroidal Nevus.

Alexander Schneider1, Peter R Pavan1, Curtis E Margo1,2, Jasmina Bajric1.   

Abstract

Melanoma-associated spongiform scleropathy contiguous to a choroidal nevus was an incidental finding in a 57-year-old woman whose eye was removed for a separate choroidal-ciliary body melanoma. All previously reported cases of melanoma-associated spongiform scleropathy, except for one, have been found adjacent to posterior uveal melanoma. The mechanism of scleral degeneration in melanoma-associated spongiform scleropathy is unknown. Few cases of posterior uveal nevi have been reported since the description of spongiform scleropathy, making assessment of the specificity of the degeneration to melanoma alone difficult. The presence of melanoma-associated scleropathy adjacent to a choroidal nevus indicates that the condition is not exclusively linked to posterior uveal melanoma.

Entities:  

Keywords:  Choroidal nevus; Melanoma-associated spongiform scleropathy; Nevus; Scleral degeneration

Year:  2018        PMID: 31367587      PMCID: PMC6615339          DOI: 10.1159/000494326

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  7 in total

Review 1.  Estimating the risk of malignant transformation of a choroidal nevus.

Authors:  Arun D Singh; Partho Kalyani; Allan Topham
Journal:  Ophthalmology       Date:  2005-10       Impact factor: 12.079

Review 2.  Choroidal nevus: a review of prevalence, features, genetics, risks, and outcomes.

Authors:  Jason L Chien; Kareem Sioufi; Thamolwan Surakiatchanukul; Jerry A Shields; Carol L Shields
Journal:  Curr Opin Ophthalmol       Date:  2017-05       Impact factor: 3.761

3.  Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma.

Authors:  Roshni U Ranjit; Ilya M Leyngold; Curtis E Margo
Journal:  Ocul Oncol Pathol       Date:  2016-07-16

4.  Melanoma associated spongiform scleropathy: characterization, biochemical and immunohistochemical studies.

Authors:  Ghassan Ayish Alyahya
Journal:  Acta Ophthalmol       Date:  2008-10       Impact factor: 3.761

5.  Matrix metalloproteinase-2 is expressed in melanoma-associated spongiform scleropathy.

Authors:  Ghassan Ayish Alyahya; Miriam Kolko; Jan Ulrik Prause; Boye Schnack Nielsen; Jinmei Wang; Steffen Heegaard
Journal:  Invest Ophthalmol Vis Sci       Date:  2008-07       Impact factor: 4.799

6.  Characterization of melanoma associated spongiform scleropathy.

Authors:  Ghassan Ayish Alyahya; Steffen Heegaard; Jan Ulrik Prause
Journal:  Acta Ophthalmol Scand       Date:  2002-06

7.  Melanoma-associated spongiform scleropathy: biochemical changes and possible relation to tumour extension.

Authors:  Ghassan Ayish Alyahya; Søren M Ribel-Madsen; Steffen Heegaard; Jan Ulrik Prause; Klaus Trier
Journal:  Acta Ophthalmol Scand       Date:  2003-12
  7 in total

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