Literature DB >> 31366687

A New Perspective on HIV Diagnostics: Reinterpretation in the Age of Early Treatment.

Sheila M Keating1,2,3.   

Abstract

Early treatment of HIV infection with antiretroviral therapy in recently identified HIV-infected individuals reduces viral replication and decreases the risk of transmission. The screening and supplemental, confirmatory assays used to identify infection are influenced by early treatment and may obscure a clear diagnosis of HIV infection. In this issue of the Journal of Clinical Microbiology, Manak et al. demonstrate the impact of antiretroviral therapy on the evolution of biomarkers that have traditionally been used for identifying HIV infection (M. M. Manak, L. L. Jagodzinski, A. Shutt, J. A. Malia, et al., J Clin Microbiol 57:e00757-19, 2019, https://doi.org/10.1128/JCM.00757-19).
Copyright © 2019 American Society for Microbiology.

Entities:  

Mesh：

Year:  2019        PMID： 31366687      PMCID： PMC6760963          DOI： 10.1128/JCM.00978-19

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  12 in total

1.  Comparison of Detection Limits of Fourth- and Fifth-Generation Combination HIV Antigen-Antibody, p24 Antigen, and Viral Load Assays on Diverse HIV Isolates.

Authors:  Mars Stone; John Bainbridge; Ana M Sanchez; Sheila M Keating; Andrea Pappas; Wes Rountree; Chris Todd; Sonia Bakkour; Mark Manak; Sheila A Peel; Robert W Coombs; Eric M Ramos; M Kathleen Shriver; Paul Contestable; Sangeetha Vijaysri Nair; David H Wilson; Martin Stengelin; Gary Murphy; Indira Hewlett; Thomas N Denny; Michael P Busch
Journal:  J Clin Microbiol       Date:  2018-07-26       Impact factor: 5.948

2.  Ending the HIV Epidemic: A Plan for the United States.

Authors:  Anthony S Fauci; Robert R Redfield; George Sigounas; Michael D Weahkee; Brett P Giroir
Journal:  JAMA       Date:  2019-03-05       Impact factor: 56.272

3.  A Strategy for PrEP Clinicians to Manage Ambiguous HIV Test Results During Follow-up Visits.

Authors:  Dawn K Smith; William M Switzer; Philip Peters; Kevin P Delaney; Timothy C Granade; Silvina Masciotra; Luke Shouse; John T Brooks
Journal:  Open Forum Infect Dis       Date:  2018-07-21       Impact factor: 3.835

4.  Performance of the Alere Determine™ HIV-1/2 Ag/Ab Combo Rapid Test with algorithm-defined acute HIV-1 infection specimens.

Authors:  Monica M Parker; S Berry Bennett; Timothy J Sullivan; Sally Fordan; Laura G Wesolowski; Kelly Wroblewski; Anne M Gaynor
Journal:  J Clin Virol       Date:  2018-05-14       Impact factor: 3.168

5.  Clinical evaluation of BioPlex 2200 HIV Ag-Ab, an automated screening method providing discrete detection of HIV-1 p24 antigen, HIV-1 antibody, and HIV-2 antibody.

Authors:  Maud Salmona; Severine Delarue; Constance Delaugerre; François Simon; Sarah Maylin
Journal:  J Clin Microbiol       Date:  2013-10-23       Impact factor: 5.948

6.  Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size.

Authors:  Vivek Jain; Wendy Hartogensis; Peter Bacchetti; Peter W Hunt; Hiroyu Hatano; Elizabeth Sinclair; Lorrie Epling; Tzong-Hae Lee; Michael P Busch; Joseph M McCune; Christopher D Pilcher; Frederick M Hecht; Steven G Deeks
Journal:  J Infect Dis       Date:  2013-07-12       Impact factor: 5.226

7.  Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel.

Authors:  Michael S Saag; Constance A Benson; Rajesh T Gandhi; Jennifer F Hoy; Raphael J Landovitz; Michael J Mugavero; Paul E Sax; Davey M Smith; Melanie A Thompson; Susan P Buchbinder; Carlos Del Rio; Joseph J Eron; Gerd Fätkenheuer; Huldrych F Günthard; Jean-Michel Molina; Donna M Jacobsen; Paul A Volberding
Journal:  JAMA       Date:  2018-07-24       Impact factor: 56.272

8.  Initiation of Antiretroviral Therapy During Acute HIV-1 Infection Leads to a High Rate of Nonreactive HIV Serology.

Authors:  Mark S de Souza; Suteeraporn Pinyakorn; Siriwat Akapirat; Supanit Pattanachaiwit; James L K Fletcher; Nitiya Chomchey; Eugene D Kroon; Sasiwimol Ubolyam; Nelson L Michael; Merlin L Robb; Praphan Phanuphak; Jerome H Kim; Nittaya Phanuphak; Jintanat Ananworanich
Journal:  Clin Infect Dis       Date:  2016-06-17       Impact factor: 9.079

9.  UNAIDS 90-90-90 targets to end the AIDS epidemic by 2020 are not realistic: comment on "Can the UNAIDS 90-90-90 target be achieved? A systematic analysis of national HIV treatment cascades".

Authors:  Luchuo Engelbert Bain; Clovis Nkoke; Jean Jacques N Noubiap
Journal:  BMJ Glob Health       Date:  2017-03-07

10.  HIV DNA Set Point is Rapidly Established in Acute HIV Infection and Dramatically Reduced by Early ART.

Authors:  Jintanat Ananworanich; Nicolas Chomont; Leigh Ann Eller; Eugene Kroon; Sodsai Tovanabutra; Meera Bose; Martin Nau; James L K Fletcher; Somporn Tipsuk; Claire Vandergeeten; Robert J O'Connell; Suteeraporn Pinyakorn; Nelson Michael; Nittaya Phanuphak; Merlin L Robb
Journal:  EBioMedicine       Date:  2016-07-20       Impact factor: 8.143
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