Shun-Ichi Ariizumi1, Daisuke Ban2, Yuta Abe3, Takafumi Kumamoto4, Satoshi Koizumi5, Minoru Tanabe2, Masahiro Shinoda3, Itaru Endo4, Takehito Otsubo5, Masakazu Yamamoto6. 1. Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan. 2. Department of Hepato-Biliary-Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan. 3. Department of Surgery, School of Medicine, Keio University, Tokyo, Japan. 4. Department of Gastroenterological Surgery, Yokohama City University, Graduate School of Medicine, Yokohama, Japan. 5. Division of Gastroenterological and General Surgery, St. Marianna University School of Medicine, Kawasaki, Japan. 6. Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University, Tokyo, Japan yamamoto.masakazu@twmu.ac.jp.
Abstract
BACKGROUND/AIM: The aim of the study was to evaluate surgical outcomes of patients with high-signal intensity (SI) image hepatocellular carcinoma (HCC). PATIENTS AND METHODS: Between 2008 and 2013, 257 HCC patients were retrospectively evaluated. A total of 21 patients were diagnosed as high-SI image HCC, 215 as low-SI image HCC, and 21 patients as mixed (high and low)-SI image HCC in the hepatobiliary (HB) phase of MRI. Five-year overall survival (OS) and recurrence-free survival (RFS) were compared among patient groups. RESULTS: The 5-year OS and RFS rates were significantly higher in patients with high-SI image HCC (100% and 56%) than in patients with low-SI image HCC (71%; p=0.097 and 38%; p=0.0209) and in patients with mixed-SI image HCC (73%; p=0.0329 and 9%; p=0.0021). High-SI image was an independent prognostic factor for OS (relative risk 0.167, p=0.0178) and RFS (relative risk 0.471, p=0.0322) on multivariate analysis. CONCLUSION: Patients with high-SI image HCC showed favorable long-term survival after curative surgery. Copyright
BACKGROUND/AIM: The aim of the study was to evaluate surgical outcomes of patients with high-signal intensity (SI) image hepatocellular carcinoma (HCC). PATIENTS AND METHODS: Between 2008 and 2013, 257 HCC patients were retrospectively evaluated. A total of 21 patients were diagnosed as high-SI image HCC, 215 as low-SI image HCC, and 21 patients as mixed (high and low)-SI image HCC in the hepatobiliary (HB) phase of MRI. Five-year overall survival (OS) and recurrence-free survival (RFS) were compared among patient groups. RESULTS: The 5-year OS and RFS rates were significantly higher in patients with high-SI image HCC (100% and 56%) than in patients with low-SI image HCC (71%; p=0.097 and 38%; p=0.0209) and in patients with mixed-SI image HCC (73%; p=0.0329 and 9%; p=0.0021). High-SI image was an independent prognostic factor for OS (relative risk 0.167, p=0.0178) and RFS (relative risk 0.471, p=0.0322) on multivariate analysis. CONCLUSION:Patients with high-SI image HCC showed favorable long-term survival after curative surgery. Copyright
Authors: Osman Öcal; Michael Ingrisch; Muzaffer Reha Ümütlü; Bora Peynircioglu; Christian Loewe; Otto van Delden; Vincent Vandecaveye; Bernhard Gebauer; Christoph J Zech; Christian Sengel; Irene Bargellini; Roberto Iezzi; Alberto Benito; Maciej Pech; Peter Malfertheiner; Jens Ricke; Max Seidensticker Journal: Br J Cancer Date: 2021-10-22 Impact factor: 7.640
Authors: Osman Öcal; Daniel Rössler; Antonio Gasbarrini; Thomas Berg; Heinz-Josef Klümpen; Irene Bargellini; Bora Peynircioglu; Otto van Delden; Christian Schulz; Kerstin Schütte; Roberto Iezzi; Maciej Pech; Peter Malfertheiner; Bruno Sangro; Jens Ricke; Max Seidensticker Journal: J Cancer Res Clin Oncol Date: 2021-09-20 Impact factor: 4.322