Alison Crawford1, Dean A Tripp2, J Curtis Nickel3, Lesley Carr4, Robert Moldwin5, Laura Katz6, Abi Muere1. 1. Department of Psychology, Queen's University, Kingston, ON, Canada. 2. Departments of Psychology, Urology, & Anesthesiology, Queen's University, Kingston, ON, Canada. 3. Department of Urology Queen's University, Kingston, ON, Canada. 4. Department of Surgery, University of Toronto, Toronto, ON, Canada. 5. Department of Urology, Hosftra University School of Medicine, New Hyde Park, NY, United States. 6. Michael G. DeGroote Pain Clinic, McMaster University Hospital, Hamilton, ON, Canada.
Abstract
INTRODUCTION: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a devastating urological chronic pelvic pain condition with an unknown etiology. Evidence-based psychological strategies are becoming more successful for symptom management as we learn more about the targets for intervention. Previous research has established an indirect relationship between depression and pain through catastrophizing, but there have yet to be studies examining the emerging role of emotion regulation in this relationship. METHODS: Women with IC/BPS were recruited from tertiary care clinics in Canada and the U.S. between 2013 and 2018. Patients completed questionnaires, including demographics and scores for pain, depression, catastrophizing, and difficulties in emotion regulation at baseline, six months, and one year. Serial mediation was used to test models of pain, catastrophizing, and depression. RESULTS: A total of 135 women with IC/BPS completed all three time points. The only significant indirect path was from baseline depression to catastrophizing at six months to pain at one year (b=0.10; confidence interval [CI] 0.0049-0.2520). A followup analysis demonstrated that helplessness was the key factor of catastrophizing driving this relationship (b=0.17; CI 0.0282-0.3826). CONCLUSIONS: Reducing feelings of helplessness and increasing patient feelings of control are important ways to limit the effect of low mood on patient pain experience. De-catastrophizing interventions should be part of the referral strategy for IC/BPS symptom management.
INTRODUCTION: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a devastating urological chronic pelvic pain condition with an unknown etiology. Evidence-based psychological strategies are becoming more successful for symptom management as we learn more about the targets for intervention. Previous research has established an indirect relationship between depression and pain through catastrophizing, but there have yet to be studies examining the emerging role of emotion regulation in this relationship. METHODS:Women with IC/BPS were recruited from tertiary care clinics in Canada and the U.S. between 2013 and 2018. Patients completed questionnaires, including demographics and scores for pain, depression, catastrophizing, and difficulties in emotion regulation at baseline, six months, and one year. Serial mediation was used to test models of pain, catastrophizing, and depression. RESULTS: A total of 135 women with IC/BPS completed all three time points. The only significant indirect path was from baseline depression to catastrophizing at six months to pain at one year (b=0.10; confidence interval [CI] 0.0049-0.2520). A followup analysis demonstrated that helplessness was the key factor of catastrophizing driving this relationship (b=0.17; CI 0.0282-0.3826). CONCLUSIONS: Reducing feelings of helplessness and increasing patient feelings of control are important ways to limit the effect of low mood on patientpain experience. De-catastrophizing interventions should be part of the referral strategy for IC/BPS symptom management.
Authors: Robert H Dworkin; Dennis C Turk; John T Farrar; Jennifer A Haythornthwaite; Mark P Jensen; Nathaniel P Katz; Robert D Kerns; Gerold Stucki; Robert R Allen; Nicholas Bellamy; Daniel B Carr; Julie Chandler; Penney Cowan; Raymond Dionne; Bradley S Galer; Sharon Hertz; Alejandro R Jadad; Lynn D Kramer; Donald C Manning; Susan Martin; Cynthia G McCormick; Michael P McDermott; Patrick McGrath; Steve Quessy; Bob A Rappaport; Wendye Robbins; James P Robinson; Margaret Rothman; Mike A Royal; Lee Simon; Joseph W Stauffer; Wendy Stein; Jane Tollett; Joachim Wernicke; James Witter Journal: Pain Date: 2005-01 Impact factor: 6.961
Authors: Abi Muere; Dean A Tripp; J Curtis Nickel; Kerri-Lynn Kelly; Robert Mayer; Michel Pontari; Robert Moldwin; Lesley K Carr; Claire C Yang; Jorgen Nordling Journal: Pain Manag Nurs Date: 2018-03-01 Impact factor: 1.929
Authors: Dean A Tripp; J Curtis Nickel; Jennifer Wong; Michel Pontari; Robert Moldwin; Robert Mayer; Lesley K Carr; Ragi Doggweiler; Claire C Yang; Nagendra Mishra; Jorgen Nordling Journal: Eur Urol Date: 2012-05-18 Impact factor: 20.096
Authors: Laura Katz; Dean A Tripp; Lesley K Carr; Robert Mayer; Robert M Moldwin; J Curtis Nickel Journal: BJU Int Date: 2017-05-05 Impact factor: 5.588
Authors: J Curtis Nickel; Dean A Tripp; Michel Pontari; Robert Moldwin; Robert Mayer; Lesley K Carr; Raggi Doggweiler; Claire C Yang; Nagendra Mishra; Jorgen Nordling Journal: J Urol Date: 2010-01 Impact factor: 7.450
Authors: Lucía Sanromán; Patricia Catalá; Carmen Écija; Carlos Suso-Ribera; Jesús San Román; Cecilia Peñacoba Journal: Int J Environ Res Public Health Date: 2022-04-01 Impact factor: 3.390
Authors: Linda Fischer-Grote; Vera Fössing; Martin Aigner; Markus Boeckle; Elisabeth Fehrmann Journal: Int Urogynecol J Date: 2022-03-09 Impact factor: 1.932
Authors: Cecilia Peñacoba; Maria Ángeles Pastor-Mira; Carlos Suso-Ribera; Patricia Catalá; Ainara Nardi-Rodríguez; Sofía López-Roig Journal: Int J Environ Res Public Health Date: 2021-05-18 Impact factor: 3.390