| Literature DB >> 31362198 |
Murhaf Jalab1, Megan E Critchley2, Charlotte M Taylor2, Clare L Lawrence1, Robert B Smith3.
Abstract
The synthesis of a variety of 1,8-substituted anthraquinones, anthrones and bianthrones and their potential as antifungal agents is evaluated. Preliminary screening against Schizosaccharomyces pombe (S. pombe), a fission yeast, and Saccharomyces cerevisiae (S. cerevisiae), a budding yeast, is reported. Both these yeast species demonstrate close homologue to a number of pathogenic fungi.Entities:
Keywords: Anthraquinones; Anthrones; Antifungal; Bianthrones; Non-azole; Yeasts
Year: 2019 PMID： 31362198 DOI： 10.1016/j.bioorg.2019.103151
Source DB: PubMed Journal: Bioorg Chem ISSN： 0045-2068 Impact factor: 5.275