Literature DB >> 31361863

Current practices in the delivery of pharmacogenomics: Impact of the recommendations of the Pharmacy Practice Model Summit.

John Valgus1, Kristin W Weitzel2, Josh F Peterson3, Daniel J Crona4, Christine M Formea5.   

Abstract

PURPOSE: This report examines and evaluates pharmacogenomics as an emerging science as it relates to the Practice Advancement Initiative and its predecessor the Pharmacy Practice Model Initiative's consensus statements for optimal pharmacy practice models.
SUMMARY: Pharmacogenomics is one of many emerging sciences to impact medication management and delivery of patient care. Increasingly, biomarkers are included in drug labeling and can assist pharmacists with personalizing medicine to optimize patient therapies and avoid adverse effects. The 2011 ASHP Pharmacy Practice Model Summit generated a list of 147 consensus statements for optimal pharmacy practice. Of these, 1 statement explicitly describes adjustment of drug regimens based on genetic factors as an essential activity of pharmacist-provided drug regimens, and 9 other statements provide additional support for incorporation of this emerging science into all aspects of patient care provided by pharmacists. We describe 4 institutions that have made significant inroads to implementing pharmacogenomics, to provide a framework and serve as resources for other institutions initiating their own pharmacogenomics implementation journeys.
CONCLUSION: Through prioritized efforts of the pharmacy profession and health care institutions, pharmacogenomics will be disseminated and implemented, and the goal of the Pharmacy Practice Model Initiative's consensus statements of improving health care using patients' genetic characteristics will be realized. © American Society of Health-System Pharmacists 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  pharmacogenetics; pharmacogenomics; pharmacy; pharmacy service/hospital; precision medicine

Mesh:

Year:  2019        PMID: 31361863      PMCID: PMC6480071          DOI: 10.1093/ajhp/zxz024

Source DB:  PubMed          Journal:  Am J Health Syst Pharm        ISSN: 1079-2082            Impact factor:   2.637


  17 in total

1.  An ethical and legal overview of pharmacogenomics: perspectives and issues.

Authors:  Guillaume Sillon; Yann Joly; Sabrina Feldman; Denise Avard
Journal:  Med Law       Date:  2008-12

2.  Impact of genotype-guided dosing on anticoagulation visits for adults starting warfarin: a randomized controlled trial.

Authors:  Daniel E Jonas; James P Evans; Howard L McLeod; Shannon Brode; Leslie A Lange; Mary L Young; Betsy Bryant Shilliday; Michelle Martensen Bardsley; Nia J Swinton-Jenkins; Karen E Weck
Journal:  Pharmacogenomics       Date:  2013-10       Impact factor: 2.533

3.  Institutional profile. UNC Institute for Pharmacogenomics and Individualized Therapy: interdisciplinary research for individual care.

Authors:  Tejinder K Rakhra-Burris; J Todd Auman; Patricia Deverka; Lynn G Dressler; James P Evans; Richard M Goldberg; Tammy M Havener; Janelle M Hoskins; Daniel E Jonas; Kevin M Long; Alison A Motsinger-Reif; William J Irvin; Kristy L Richards; Mary W Roederer; John M Valgus; Marcia van Riper; John A Vernon; William C Zamboni; Michael J Wagner; Christine M Walko; Karen E Weck; Tim Wiltshire; Howard L McLeod
Journal:  Pharmacogenomics       Date:  2010-01       Impact factor: 2.533

4.  The consensus of the Pharmacy Practice Model Summit.

Authors: 
Journal:  Am J Health Syst Pharm       Date:  2011-06-15       Impact factor: 2.637

5.  Assessment of the pharmacogenomics educational needs of pharmacists.

Authors:  Kristen B McCullough; Christine M Formea; Kevin D Berg; Julianna A Burzynski; Julie L Cunningham; Narith N Ou; Maria I Rudis; Joanna L Stollings; Wayne T Nicholson
Journal:  Am J Pharm Educ       Date:  2011-04-11       Impact factor: 2.047

6.  Genotype-guided tamoxifen dosing increases active metabolite exposure in women with reduced CYP2D6 metabolism: a multicenter study.

Authors:  William J Irvin; Christine M Walko; Karen E Weck; Joseph G Ibrahim; Wing K Chiu; E Claire Dees; Susan G Moore; Oludamilola A Olajide; Mark L Graham; Sean T Canale; Rachel E Raab; Steven W Corso; Jeffrey M Peppercorn; Steven M Anderson; Kenneth J Friedman; Evan T Ogburn; Zeruesenay Desta; David A Flockhart; Howard L McLeod; James P Evans; Lisa A Carey
Journal:  J Clin Oncol       Date:  2011-07-18       Impact factor: 44.544

7.  Preemptive genotyping for personalized medicine: design of the right drug, right dose, right time-using genomic data to individualize treatment protocol.

Authors:  Suzette J Bielinski; Janet E Olson; Jyotishman Pathak; Richard M Weinshilboum; Liewei Wang; Kelly J Lyke; Euijung Ryu; Paul V Targonski; Michael D Van Norstrand; Matthew A Hathcock; Paul Y Takahashi; Jennifer B McCormick; Kiley J Johnson; Karen J Maschke; Carolyn R Rohrer Vitek; Marissa S Ellingson; Eric D Wieben; Gianrico Farrugia; Jody A Morrisette; Keri J Kruckeberg; Jamie K Bruflat; Lisa M Peterson; Joseph H Blommel; Jennifer M Skierka; Matthew J Ferber; John L Black; Linnea M Baudhuin; Eric W Klee; Jason L Ross; Tamra L Veldhuizen; Cloann G Schultz; Pedro J Caraballo; Robert R Freimuth; Christopher G Chute; Iftikhar J Kullo
Journal:  Mayo Clin Proc       Date:  2014-01       Impact factor: 7.616

Review 8.  Genomics and drug response.

Authors:  Liewei Wang; Howard L McLeod; Richard M Weinshilboum
Journal:  N Engl J Med       Date:  2011-03-24       Impact factor: 91.245

9.  Challenges in implementing genomic medicine: the Mayo Clinic Center for Individualized Medicine.

Authors:  G Farrugia; R M Weinshilboum
Journal:  Clin Pharmacol Ther       Date:  2013-03-11       Impact factor: 6.875

10.  Electronic health record design and implementation for pharmacogenomics: a local perspective.

Authors:  Josh F Peterson; Erica Bowton; Julie R Field; Marc Beller; Jennifer Mitchell; Jonathan Schildcrout; William Gregg; Kevin Johnson; Jim N Jirjis; Dan M Roden; Jill M Pulley; Josh C Denny
Journal:  Genet Med       Date:  2013-09-05       Impact factor: 8.822

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  2 in total

1.  Adolescent perceptions of pharmacogenetic testing.

Authors:  Stephani L Stancil; Courtney Berrios; Susan Abdel-Rahman
Journal:  Pharmacogenomics       Date:  2021-04-14       Impact factor: 2.533

2.  Pharmacogenomics at the Point of Care: A Community Pharmacy Project in British Columbia.

Authors:  Samantha Breaux; Francis Arthur Derek Desrosiers; Mauricio Neira; Sunita Sinha; Corey Nislow
Journal:  J Pers Med       Date:  2020-12-24
  2 in total

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