Literature DB >> 3136037

Characterization of an invertebrate nicotinic acetylcholine receptor gene: the ard gene of Drosophila melanogaster.

E Sawruk1, I Hermans-Borgmeyer, H Betz, E D Gundelfinger.   

Abstract

The ard gene encodes a neuronal nicotinic acetylcholine receptor (AChR) protein from Drosophila (ARD protein). Cytogenetically this gene maps at position 64B/C on the left arm of the 3rd chromosome. Five introns interrupt the protein coding region of the gene, and one is found upstream of the translation start site. The ard gene thus contains less introns than vertebrate muscle AChR genes, but, with one exception, the positions of the resident introns are precisely conserved. Implications for the evolution of AChR genes are discussed.

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Year:  1988        PMID: 3136037     DOI: 10.1016/0014-5793(88)81230-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  6 in total

1.  Nicotinic acetylcholine receptors of the drosophila central nervous system.

Authors:  E D Gundelfinger; P Schloss
Journal:  J Protein Chem       Date:  1989-06

2.  A genetic analysis of the 63E-64A genomic region of Drosophila melanogaster: identification of mutations in a replication factor C subunit.

Authors:  S D Harrison; N Solomon; G M Rubin
Journal:  Genetics       Date:  1995-04       Impact factor: 4.562

3.  Negative regulatory elements upstream of a novel exon of the neuronal nicotinic acetylcholine receptor alpha 2 subunit gene.

Authors:  A Bessis; N Savatier; A Devillers-Thiéry; S Bejanin; J P Changeux
Journal:  Nucleic Acids Res       Date:  1993-05-11       Impact factor: 16.971

4.  Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria.

Authors:  J Reizer; K Finley; D Kakuda; C L MacLeod; A Reizer; M H Saier
Journal:  Protein Sci       Date:  1993-01       Impact factor: 6.725

5.  Heterogeneity of Drosophila nicotinic acetylcholine receptors: SAD, a novel developmentally regulated alpha-subunit.

Authors:  E Sawruk; P Schloss; H Betz; B Schmitt
Journal:  EMBO J       Date:  1990-09       Impact factor: 11.598

6.  The homeobox transcription factor Even-skipped regulates acquisition of electrical properties in Drosophila neurons.

Authors:  Edward C G Pym; Tony D Southall; Christopher J Mee; Andrea H Brand; Richard A Baines
Journal:  Neural Dev       Date:  2006-11-16       Impact factor: 3.842

  6 in total

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