| Literature DB >> 31358984 |
Efstathios S Giotis1, George Carnell2,3, Erik F Young4,5, Saleena Ghanny6, Patricia Soteropoulos6, Lin-Fa Wang7, Wendy S Barclay8, Michael A Skinner8, Nigel Temperton2.
Abstract
Haemagglutinin and neuraminidase surface glycoproteins of the bat influenza H17N10 virus neither bind to nor cleave sialic acid receptors, indicating that this virus employs cell entry mechanisms distinct from those of classical influenza A viruses. We observed that certain human haematopoietic cancer cell lines and canine MDCK II cells are susceptible to H17-pseudotyped viruses. We identified the human HLA-DR receptor as an entry mediator for H17 pseudotypes, suggesting that H17N10 possesses zoonotic potential.Entities:
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Year: 2019 PMID： 31358984 DOI： 10.1038/s41564-019-0517-3
Source DB: PubMed Journal: Nat Microbiol ISSN： 2058-5276 Impact factor: 17.745