Literature DB >> 31358855

The novel autophagy inhibitor ROC-325 augments the antileukemic activity of azacitidine.

Steffan T Nawrocki1, Yingchun Han2, Valeria Visconte2, Bartlomiej Przychodzen2, Claudia M Espitia1, James Phillips2, Faiz Anwer1,2, Anjali Advani2, Hetty E Carraway2, Kevin R Kelly3, Mikkael A Sekeres2, Jaroslaw P Maciejewski2, Jennifer S Carew4.   

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Year:  2019        PMID： 31358855      PMCID： PMC7462348          DOI： 10.1038/s41375-019-0529-2

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  13 in total

Review 1.  A perspective on the role of autophagy in cancer.

Authors:  Aileen R Ariosa; Vikramjit Lahiri; Yuchen Lei; Ying Yang; Zhangyuan Yin; Zhihai Zhang; Daniel J Klionsky
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2021-09-01       Impact factor: 5.187

Review 2.  Autophagy in health and disease: From molecular mechanisms to therapeutic target.

Authors:  Guang Lu; Yu Wang; Yin Shi; Zhe Zhang; Canhua Huang; Weifeng He; Chuang Wang; Han-Ming Shen
Journal:  MedComm (2020)       Date:  2022-07-10

3.  Moving beyond hydroxychloroquine: the novel lysosomal autophagy inhibitor ROC-325 shows significant potential in preclinical studies.

Authors:  Trace M Jones; Claudia Espitia; Wei Wang; Steffan T Nawrocki; Jennifer S Carew
Journal:  Cancer Commun (Lond)       Date:  2019-11-09

Review 4.  Targeting Cytoprotective Autophagy to Enhance Anticancer Therapies.

Authors:  Malina Xiao; Alice Benoit; Meriem Hasmim; Caroline Duhem; Guillaume Vogin; Guy Berchem; Muhammad Zaeem Noman; Bassam Janji
Journal:  Front Oncol       Date:  2021-02-25       Impact factor: 6.244

5.  Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine.

Authors:  Nienke Visser; Harm Jan Lourens; Gerwin Huls; Edwin Bremer; Valerie R Wiersma
Journal:  Int J Mol Sci       Date:  2021-02-26       Impact factor: 5.923

Review 6.  Mitochondrial metabolism as a target for acute myeloid leukemia treatment.

Authors:  Svetlana B Panina; Jingqi Pei; Natalia V Kirienko
Journal:  Cancer Metab       Date:  2021-04-21

Review 7.  The role of autophagy in targeted therapy for acute myeloid leukemia.

Authors:  Wenxin Du; Aixiao Xu; Yunpeng Huang; Ji Cao; Hong Zhu; Bo Yang; Xuejing Shao; Qiaojun He; Meidan Ying
Journal:  Autophagy       Date:  2020-09-22       Impact factor: 16.016

Review 8.  Autophagy Modulators in Cancer Therapy.

Authors:  Kamila Buzun; Agnieszka Gornowicz; Roman Lesyk; Krzysztof Bielawski; Anna Bielawska
Journal:  Int J Mol Sci       Date:  2021-05-28       Impact factor: 5.923

Review 9.  Molecular Mechanisms Underlying Autophagy-Mediated Treatment Resistance in Cancer.

Authors:  Cally J Ho; Sharon M Gorski
Journal:  Cancers (Basel)       Date:  2019-11-11       Impact factor: 6.639

Review 10.  Therapeutic Targeting of Autophagy for Renal Cell Carcinoma Therapy.

Authors:  Trace M Jones; Jennifer S Carew; Steffan T Nawrocki
Journal:  Cancers (Basel)       Date:  2020-05-07       Impact factor: 6.575
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