Recent advances in the biotoxicity of metal oxide nanoparticles: Impacts on plants, animals and microorganisms.

The contact between metal oxide nanoparticles (NPs) and human is more and more close with their wide applications. The inputs of metal oxide NPs to the environment are also growing every year, which causes potential environmental and human health risks. They are toxic to animals, microorganisms and plants at high concentrations, and they show different mechanisms of toxicity to different species. In addition, under complex environmental conditions, their toxic effects are often unpredictable. We have integrated the recent studies on the biotoxicity of metal oxide NPs from 2015-present, and clarified their toxic mechanism, as well as the toxic harm. It lays a foundation for further studying the toxicity and ecological risk of metal oxide NPs.