Yi-Wen Chen1, Andrew H Ramsook2, Harvey O Coxson3, Jessica Bon4, W Darlene Reid5. 1. Department of Sports Medicine, China Medical University, Taichung, Taiwan. Electronic address: yiwenchen@mail.cmu.edu.tw. 2. Department of Physical Therapy, Centre for Heart Lung Innovation, University of British Columbia, Vancouver, BC, Canada. 3. Department of Radiology, Centre for Heart Lung Innovation, University of British Columbia, Vancouver, BC, Canada. 4. Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA; VA Pittsburgh Healthcare System, Pittsburgh, PA. 5. Department of Physical Therapy, Faculty of Medicine, Interdepartment Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada; KITE - Toronto Rehab-University Health Network, Toronto, ON, Canada.
Abstract
BACKGROUND: Osteoporosis is prevalent in individuals with COPD. Updated evidence is required to complement the previous systematic review on this topic to provide best practice. The aim of this systematic review and meta-analysis was to quantitatively synthesize data from studies with respect to the prevalence and risk factors for osteoporosis among individuals with COPD. METHODS: EMBASE, CINAHL, MEDLINE, and PubMed databases were searched for articles containing the key words "COPD," "osteoporosis," "prevalence," and "risk factor." Eligibility screening, data extraction, and quality assessment of the retrieved articles were conducted independently by two reviewers. Meta-analyses were performed to determine osteoporosis prevalence and risk factors in individuals with COPD. Meta-regression analyses were conducted to explore the sources of heterogeneity. RESULTS: The pooled global prevalence from 58 studies was 38% (95% CI, 34-43). The presence of COPD increased the likelihood of having osteoporosis (OR, 2.83). Other significant risk factors for osteoporosis in COPD patients were BMI < 18.5 kg/m2 (OR, 4.26) and the presence of sarcopenia (OR, 3.65). CONCLUSIONS: Osteoporosis is prevalent in individuals with COPD, and the prevalence seems to be high and similar in many countries. Patients with COPD should be screened for osteoporosis and contributing risk factors.
BACKGROUND:Osteoporosis is prevalent in individuals with COPD. Updated evidence is required to complement the previous systematic review on this topic to provide best practice. The aim of this systematic review and meta-analysis was to quantitatively synthesize data from studies with respect to the prevalence and risk factors for osteoporosis among individuals with COPD. METHODS: EMBASE, CINAHL, MEDLINE, and PubMed databases were searched for articles containing the key words "COPD," "osteoporosis," "prevalence," and "risk factor." Eligibility screening, data extraction, and quality assessment of the retrieved articles were conducted independently by two reviewers. Meta-analyses were performed to determine osteoporosis prevalence and risk factors in individuals with COPD. Meta-regression analyses were conducted to explore the sources of heterogeneity. RESULTS: The pooled global prevalence from 58 studies was 38% (95% CI, 34-43). The presence of COPD increased the likelihood of having osteoporosis (OR, 2.83). Other significant risk factors for osteoporosis in COPDpatients were BMI < 18.5 kg/m2 (OR, 4.26) and the presence of sarcopenia (OR, 3.65). CONCLUSIONS:Osteoporosis is prevalent in individuals with COPD, and the prevalence seems to be high and similar in many countries. Patients with COPD should be screened for osteoporosis and contributing risk factors.
Authors: Shuman Yang; Na Wang; Jianmeng Wang; Lisa M Lix; William D Leslie; Baoming Yuan Journal: Arch Osteoporos Date: 2022-08-12 Impact factor: 2.879
Authors: Christian Muschitz; Ralf Harun Zwick; Judith Haschka; Hans Peter Dimai; Martina Rauner; Karin Amrein; Robert Wakolbinger; Peter Jaksch; Ernst Eber; Peter Pietschmann Journal: Wien Klin Wochenschr Date: 2021-06-16 Impact factor: 1.704
Authors: Pradeesh Sivapalan; Niklas R Jørgensen; Alexander G Mathioudakis; Josefin Eklöf; Therese Lapperre; Charlotte Suppli Ulrik; Helle F Andreassen; Karin Armbruster; Praleene Sivapalan; Julie Janner; Nina Godtfredsen; Ulla M Weinreich; Thyge L Nielsen; Niels Seersholm; Torgny Wilcke; Philipp Schuetz; Tobias W Klausen; Kristoffer Marså; Jørgen Vestbo; Jens-Ulrik Jensen Journal: Respir Res Date: 2020-10-12