Literature DB >> 31351700

Reproductive endocrinologists are the gatekeepers for male infertility care in North America: results of a North American survey on the referral patterns and characteristics of men presenting to male infertility specialists for infertility investigations.

Mary K Samplaski1, James F Smith2, Kirk C Lo3, James M Hotaling4, Susan Lau5, Ethan D Grober5, J C Trussell6, Thomas J Walsh7, Peter N Kolettis8, Victor D W Chow9, Armand S Zini10, Aaron Spitz11, Marc A Fischer12, Trustin Domes13, Scott I Zeitlin14, Eugene F Fuchs15, Jason C Hedges15, Jay I Sandlow16, Robert E Brannigan17, James M Dupree18, Marc Goldstein19, Edmund Y Ko20, Tung-Chin M Hsieh21, Jared M Bieniek22, David Shin23, Ajay K Nangia24, Keith A Jarvi25.   

Abstract

OBJECTIVE: To characterize the referral patterns and characteristics of men presenting for infertility evaluation using data obtained from the Andrology Research Consortium.
DESIGN: Standardized male infertility questionnaire.
SETTING: Male infertility centers. PATIENT(S): Men presenting for fertility evaluation. INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Demographic, infertility history, and referral data. RESULT(S): The questionnaires were completed by 4,287 men, with a mean male age of 40 years ± 7.4 years and female partners age of 37 years ± 4.9 years. Most were Caucasian (54%) with other races being less commonly represented (Asian 18.6%, and African American 5.5%). The majority (59.7%) were referred by a reproductive gynecologist, 19.4% were referred by their primary care physician, 4.2% were self-referred, and 621 (14.5%) were referred by "other." Before the male infertility investigation, 12.1% of couples had undergone intrauterine insemination, and 4.9% of couples had undergone in vitro fertilization (up to six cycles). Among the male participants, 0.9% reported using finasteride (5α-reductase inhibitor) at a dose used for androgenic alopecia, and 1.6% reported exogenous testosterone use. CONCLUSION(S): This broad North American patient survey shows that reproductive gynecologists are the de facto gateway for most male infertility referrals, with most men being assessed in the male infertility service being referred by reproductive endocrinologists. Some of the couples with apparent male factor infertility are treated with assisted reproductive technologies before a male factor investigation. The survey also identified potentially reversible causes for the male infertility including lifestyle factors such as testosterone and 5α-reductase inhibitor use.
Copyright © 2019 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Database; intrauterine insemination; in vitro fertilization; male infertility; testosterone

Mesh:

Year:  2019        PMID: 31351700     DOI: 10.1016/j.fertnstert.2019.06.011

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  5 in total

1.  Assisted reproductive technology cycles involving male factor infertility in the United States, 2017-2018: data from the National Assisted Reproductive Technology Surveillance System.

Authors:  Amy Jewett; Lee Warner; Jennifer F Kawwass; Akanksha Mehta; Michael L Eisenberg; Ajay K Nangia; James M Dupree; Stanton Honig; James M Hotaling; Dmitry M Kissin
Journal:  F S Rep       Date:  2022-03-25

2.  A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity.

Authors:  Franz S Gruber; Zoe C Johnston; Christopher Lr Barratt; Paul D Andrews
Journal:  Elife       Date:  2020-01-28       Impact factor: 8.140

Review 3.  Defining new genetic etiologies of male infertility: progress and future prospects.

Authors:  Albert Salas-Huetos; Kenneth I Aston
Journal:  Transl Androl Urol       Date:  2021-03

Review 4.  Microsurgical Management of Male Infertility: Compelling Evidence That Collaboration with Qualified Male Reproductive Urologists Enhances Assisted Reproductive Technology (ART) Outcomes.

Authors:  Jessica Marinaro; Marc Goldstein
Journal:  J Clin Med       Date:  2022-08-06       Impact factor: 4.964

5.  Online access to male factor infertility care: the challenge of finding a specialist.

Authors:  Arighno Das; Anne Darves-Bornoz; Tejas Joshi; Mary Kate Keeter; James M Wren; Nelson E Bennett; Robert E Brannigan; Joshua A Halpern
Journal:  F S Rep       Date:  2020-09-25
  5 in total

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