I T Mahu1, P J Conrod2, S P Barrett3, A Sako4, J Swansburg3, M Lawrence3, F Laroque5, J F Morin5, A Chinneck3, R Nogueira-Arjona3, S H Stewart6. 1. Department of Psychology and Neuroscience, Dalhousie University, Life Sciences Centre, 1355 Oxford Street, PO BOX 15000, Halifax, Nova Scotia B3H 4R2, Canada. Electronic address: ioan.tiberiu.mahu@dal.ca. 2. Department of Psychiatry, University of Montreal, Ste. Justine Hospital, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, Quebec H3T 1C4, Canada. 3. Department of Psychology and Neuroscience, Dalhousie University, Life Sciences Centre, 1355 Oxford Street, PO BOX 15000, Halifax, Nova Scotia B3H 4R2, Canada. 4. Quebec-Atlantic Node, Canadian Research Initiative in Substance Misuse, Centre de Recherche du CHUM, 900 rue St-Denis, R06-428, Montréal, Québec H2X 0A9, Canada. 5. Department of Psychology, University of Montreal, Ste. Justine Hospital, 3175 Chemin de la Côte-Sainte-Catherine, Montréal, Quebec H3T 1C4, Canada. 6. Department of Psychiatry, Dalhousie University, 5909 Veterans' Memorial Lane, 8th Floor, Abbie J. Lane Memorial Building, QEII Health Sciences Centre, Halifax, Nova Scotia B3H 2E2, Canada; Department of Psychology and Neuroscience, Dalhousie University, Life Sciences Centre, 1355 Oxford Street, PO BOX 15000, Halifax, Nova Scotia B3H 4R2, Canada.
Abstract
OBJECTIVE: A mainstay treatment for opioid addiction in North America is methadone maintenance therapy (MMT) - a form of opiate agonist therapy (OAT). While efficacious for treating opioid addiction, MMT fails to address the concurrent polysubstance use that is common among opioid dependent clients. Moreover, psychosocial approaches for addressing polysubstance use during MMT are lacking. Our study's goals were to validate the use of the four-factor personality model of substance use vulnerability in MMT clients, and to demonstrate theoretically-relevant relationships of personality to concurrent substance use while receiving MMT. METHOD: Respondents included 138 daily-witnessed MMT clients (65.9% male, 79.7% Caucasian), mean age (SD) 40.18 (11.56), recruited across four Canadian MMT clinics. Bayesian confirmatory factor analysis was used to establish the structural validity of the four-factor personality model of substance use vulnerability (operationalized with the Substance Use Risk Profile Scale [SURPS]) in MMT clients. SURPS personality scores were then used as predictors for specific forms of recent (past 30-day) substance use. RESULTS: Using a latent hierarchal model, hopelessness was associated with recent opioid use; anxiety sensitivity with recent tranquilizer use; and sensation seeking with recent alcohol, cannabis, and stimulant use. CONCLUSION: Personality is associated with substance use patterns and may be an appropriate target for intervention for those undergoing MMT to reduce opioid use, and potentially dangerous concurrent use of other drugs, while receiving methadone.
OBJECTIVE: A mainstay treatment for opioid addiction in North America is methadone maintenance therapy (MMT) - a form of opiate agonist therapy (OAT). While efficacious for treating opioid addiction, MMT fails to address the concurrent polysubstance use that is common among opioid dependent clients. Moreover, psychosocial approaches for addressing polysubstance use during MMT are lacking. Our study's goals were to validate the use of the four-factor personality model of substance use vulnerability in MMT clients, and to demonstrate theoretically-relevant relationships of personality to concurrent substance use while receiving MMT. METHOD: Respondents included 138 daily-witnessed MMT clients (65.9% male, 79.7% Caucasian), mean age (SD) 40.18 (11.56), recruited across four Canadian MMT clinics. Bayesian confirmatory factor analysis was used to establish the structural validity of the four-factor personality model of substance use vulnerability (operationalized with the Substance Use Risk Profile Scale [SURPS]) in MMT clients. SURPS personality scores were then used as predictors for specific forms of recent (past 30-day) substance use. RESULTS: Using a latent hierarchal model, hopelessness was associated with recent opioid use; anxiety sensitivity with recent tranquilizer use; and sensation seeking with recent alcohol, cannabis, and stimulant use. CONCLUSION: Personality is associated with substance use patterns and may be an appropriate target for intervention for those undergoing MMT to reduce opioid use, and potentially dangerous concurrent use of other drugs, while receiving methadone.
Authors: Sherry H Stewart; Annie Chinneck; Kara Thompson; Mohammad H Afzali; Raquel Nogueira-Arjona; Ioan T Mahu; Patricia J Conrod Journal: Front Psychiatry Date: 2021-04-27 Impact factor: 4.157
Authors: Jessica Heil; Stefan Zajic; Emily Albertson; Andrew Brangan; Iris Jones; Wendy Roberts; Michael Sabia; Elliot Bodofsky; Alissa Resch; Rachel Rafeq; Rachel Haroz; Russell Buono; Thomas N Ferraro; Laura Scheinfeldt; Matthew Salzman; Kaitlan Baston Journal: BMC Med Genomics Date: 2021-01-07 Impact factor: 3.063