Literature DB >> 31350528

Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function.

Yandan Chen1, Chunxu Yao1, Yincheng Teng2, Rongzhen Jiang2, Xinxin Huang3, Sheng Liu4, Jun Wan4,5, Hal E Broxmeyer6, Bin Guo7.   

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Year:  2019        PMID： 31350528      PMCID： PMC7047760          DOI： 10.1038/s41375-019-0528-3

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  14 in total

1.  DUSP16 is a regulator of human hematopoietic stem and progenitor cells and promotes their expansion ex vivo.

Authors:  Xuepeng Wang; Hal E Broxmeyer
Journal:  Leukemia       Date:  2020-10-19       Impact factor: 11.528

2.  Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function.

Authors:  Maegan L Capitano; Safa F Mohamad; Scott Cooper; Bin Guo; Xinxin Huang; Andrea M Gunawan; Carol Sampson; James Ropa; Edward F Srour; Christie M Orschell; Hal E Broxmeyer
Journal:  J Clin Invest       Date:  2021-01-04       Impact factor: 14.808

3.  ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress.

Authors:  Yandan Chen; Shuyi Fang; Qingwei Ding; Rongzhen Jiang; Jiefeng He; Qin Wang; Yuting Jin; Xinxin Huang; Sheng Liu; Maegan L Capitano; Thao Trinh; Yincheng Teng; Qingyou Meng; Jun Wan; Hal E Broxmeyer; Bin Guo
Journal:  J Clin Invest       Date:  2021-10-15       Impact factor: 14.808

4.  CaMKK2 Knockout Bone Marrow Cells Collected/Processed in Low Oxygen (Physioxia) Suggests CaMKK2 as a Hematopoietic Stem to Progenitor Differentiation Fate Determinant.

Authors:  Hal E Broxmeyer; James Ropa; Maegan L Capitano; Scott Cooper; Luigi Racioppi; Uma Sankar
Journal:  Stem Cell Rev Rep       Date:  2022-03-09       Impact factor: 6.692

5.  Collection and Processing of Mobilized Mouse Peripheral Blood at Lowered Oxygen Tension Yields Enhanced Numbers of Hematopoietic Stem Cells.

Authors:  Arafat Aljoufi; Scott Cooper; Hal E Broxmeyer
Journal:  Stem Cell Rev Rep       Date:  2020-10       Impact factor: 5.739

6.  Leptin receptor, a surface marker for a subset of highly engrafting long-term functional hematopoietic stem cells.

Authors:  Thao Trinh; James Ropa; Arafat Aljoufi; Scott Cooper; Anthony Sinn; Edward F Srour; Hal E Broxmeyer
Journal:  Leukemia       Date:  2020-11-07       Impact factor: 11.528

7.  Enhanced collection of phenotypic and engrafting human cord blood hematopoietic stem cells at 4°C.

Authors:  Hal E Broxmeyer; Scott Cooper; Maegan L Capitano
Journal:  Stem Cells       Date:  2020-07-04       Impact factor: 6.277

8.  CXCL15/Lungkine has suppressive activity on proliferation and expansion of multi-potential, erythroid, granulocyte and macrophage progenitors in S-phase specific manner.

Authors:  Hal E Broxmeyer; Scott H Cooper; James Ropa
Journal:  Blood Cells Mol Dis       Date:  2021-07-03       Impact factor: 2.372

Review 9.  Past, present, and future efforts to enhance the efficacy of cord blood hematopoietic cell transplantation.

Authors:  Xinxin Huang; Bin Guo; Maegan Capitano; Hal E Broxmeyer
Journal:  F1000Res       Date:  2019-10-31

10.  The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells.

Authors:  Lijian Shao; Adedamola Elujoba-Bridenstine; Katherine E Zink; Laura M Sanchez; Brian J Cox; Karen E Pollok; Anthony L Sinn; Barbara J Bailey; Emily C Sims; Scott H Cooper; Hal E Broxmeyer; Kostandin V Pajcini; Owen J Tamplin
Journal:  Blood       Date:  2021-02-11       Impact factor: 25.476
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