Literature DB >> 31350231

'Enemy within': an interesting cause for anemia during warfarin therapy for atrial fibrillation.

Anita Ann Sunny1, Josy Vallipalam1, Balakrishnan Ramasamy1, Rajesh Shankar Iyer1.   

Abstract

The oral anticoagulant warfarin is a vitamin K antagonist and is considered the first line anticoagulant in valvular atrial fibrillation. However prothrombin time should be closely monitored, drug interactions checked and compliance regarding diet ensured when the patient is on warfarin therapy. Anaemia should be looked for, evaluated for the cause and corrected since it is an independent predictor of bleeding and thrombotic episodes during warfarin therapy for atrial fibrillation We present an interesting case of anaemia which developed during warfarin therapy for atrial fibrillation. The patient was on amiodarone and was consuming leafy vegetables resulting in frequent raise in prothrombin time during which time she developed bleeding into the right femoral pseudoaneurysm which had developed following catheterisation for thrombectomy. Surgical correction of pseudoaneurysm was done, comedication was changed and diet compliance ensured which resulted in the subsequent maintenance of prothrombin time in the therapeutic range and steady haemoglobin levels. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  drug interactions; warfarin therapy

Mesh:

Substances:

Year:  2019        PMID: 31350231      PMCID: PMC6663219          DOI: 10.1136/bcr-2019-230274

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

1.  American Heart Association/American College of Cardiology Foundation guide to warfarin therapy.

Authors:  Jack Hirsh; Valentin Fuster; Jack Ansell; Jonathan L Halperin
Journal:  J Am Coll Cardiol       Date:  2003-05-07       Impact factor: 24.094

2.  Simultaneous use of amiodarone influences warfarin maintenance dose but is not associated with adverse events.

Authors:  Paulo Caleb Junior Lima Santos; Renata Alonso Gadi Soares; Celia Maria Cassaro Strunz; Max Grinberg; João Fernando M Ferreira; Luiz Antônio Machado Cesar; Maurício Scanavacca; Jose Eduardo Krieger; Alexandre Costa Pereira
Journal:  J Manag Care Spec Pharm       Date:  2014-04

3.  Anemia predicts thromboembolic events, bleeding complications and mortality in patients with atrial fibrillation: insights from the RE-LY trial.

Authors:  B D Westenbrink; M Alings; S J Connolly; J Eikelboom; M D Ezekowitz; J Oldgren; S Yang; J Pongue; S Yusuf; L Wallentin; W H van Gilst
Journal:  J Thromb Haemost       Date:  2015-03-30       Impact factor: 5.824

4.  Incidence of pseudoaneurysm after diagnostic and therapeutic angiography.

Authors:  R Katzenschlager; A Ugurluoglu; A Ahmadi; M Hülsmann; R Koppensteiner; E Larch; T Maca; E Minar; A Stümpflen; H Ehringer
Journal:  Radiology       Date:  1995-05       Impact factor: 11.105

5.  Clinical observations with the amiodarone/warfarin interaction: dosing relationships with long-term therapy.

Authors:  Cynthia A Sanoski; Jerry L Bauman
Journal:  Chest       Date:  2002-01       Impact factor: 9.410

6.  Traumatic Penile Pseudoaneurysm After Straddle Injury Presenting With Life Threatening Anemia: A Unique Case and a Diagnostic Challenge.

Authors:  Muhannad Alsyouf; Phillip Stokes; Jason Smith; Akin Amasyali; David Chamberlin
Journal:  Urology       Date:  2018-11-22       Impact factor: 2.649

Review 7.  Anemia: An Independent Predictor Of Adverse Outcomes In Older Patients With Atrial Fibrillation.

Authors:  Ali N Ali; Nandkishor V Athavale; Ahmed H Abdelhafiz
Journal:  J Atr Fibrillation       Date:  2016-04-30

Review 8.  Visceral artery pseudoaneurysms: two case reports and a review of the literature.

Authors:  Amna Abdelgabar; Olivier d'Archambeau; Joachim Maes; Filip Van den Brande; Peter Cools; Roger R Rutsaert
Journal:  J Med Case Rep       Date:  2017-05-04

9.  Huge Pseudoaneurysm of the Femoral Artery after Internal Fixation of Femoral Trochanteric Fracture.

Authors:  Hideyuki Kinoshita; Masayuki Hashimoto; Jiro Hirayama; Kouji Fujita; Yoshio Takeuchi; Junichi Iwasaki; Hironori Yamasaki; Mitsuhiro Kitamura; Seiji Ohtori; Tsuguo Morikawa
Journal:  Case Rep Orthop       Date:  2018-07-25
  9 in total

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