| Literature DB >> 31350231 |
Anita Ann Sunny1, Josy Vallipalam1, Balakrishnan Ramasamy1, Rajesh Shankar Iyer1.
Abstract
The oral anticoagulant warfarin is a vitamin K antagonist and is considered the first line anticoagulant in valvular atrial fibrillation. However prothrombin time should be closely monitored, drug interactions checked and compliance regarding diet ensured when the patient is on warfarin therapy. Anaemia should be looked for, evaluated for the cause and corrected since it is an independent predictor of bleeding and thrombotic episodes during warfarin therapy for atrial fibrillation We present an interesting case of anaemia which developed during warfarin therapy for atrial fibrillation. The patient was on amiodarone and was consuming leafy vegetables resulting in frequent raise in prothrombin time during which time she developed bleeding into the right femoral pseudoaneurysm which had developed following catheterisation for thrombectomy. Surgical correction of pseudoaneurysm was done, comedication was changed and diet compliance ensured which resulted in the subsequent maintenance of prothrombin time in the therapeutic range and steady haemoglobin levels. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: drug interactions; warfarin therapy
Mesh:
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Year: 2019 PMID: 31350231 PMCID: PMC6663219 DOI: 10.1136/bcr-2019-230274
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X