Literature DB >> 31350229

Fatality from potassium gold cyanide poisoning.

Elizabeth Harmon1, Jacob Lebin1, David Murphy1, Bjorn Watsjold1.   

Abstract

While potassium cyanide poisoning has been well described, the toxicity of potassium gold cyanide is less well understood. This case describes an 84-year-old man who presented after an intentional ingestion of 0.5-1 teaspoons of potassium gold cyanide. Despite antidotal therapy, the patient rapidly developed severe lactic acidosis, multiorgan dysfunction and ultimately expired. While the patient's clinical findings were consistent with acute cyanide poisoning, a serum cyanide level was below the toxic threshold. Previous reports have suggested that gold toxicity may also contribute to the effects of potassium gold cyanide, and may have played a role in the patient's rapid decline. In addition to treatment of cyanide toxicity, management of acute gold toxicity should also be considered in potassium gold cyanide ingestion. © BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  emergency medicine; poisoning

Mesh:

Substances:

Year:  2019        PMID: 31350229      PMCID: PMC6663265          DOI: 10.1136/bcr-2019-229947

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  9 in total

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Journal:  Anaesthesia       Date:  1986-09       Impact factor: 6.955

2.  Poisoning with gold potassium cyanide and other metallic cyanides in a jeweler.

Authors:  Camila Prochalska; Bruno Megarbane; Souleiman El Balkhi; Joël Poupon; Frédéric J Baud; Robert Garnier
Journal:  Clin Toxicol (Phila)       Date:  2014 Sep-Oct       Impact factor: 4.467

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Authors:  Anthony P Morocco
Journal:  Crit Care Clin       Date:  2005-10       Impact factor: 3.598

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Authors:  G G Graham; M W Whitehouse; G R Bushell
Journal:  Inflammopharmacology       Date:  2008-06       Impact factor: 4.473

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Authors:  W F Kean; I R L Kean
Journal:  Inflammopharmacology       Date:  2008-06       Impact factor: 4.473

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Authors:  S N Vogel; T R Sultan; R P Ten Eyck
Journal:  Clin Toxicol       Date:  1981-03       Impact factor: 4.467

  9 in total
  1 in total

1.  Diagnosis of lethal cyanide poisoning. Analysis by Anion-Exchange Chromatography with Pulsed Amperometric Detection.

Authors:  Pietro Zuccarello; Giulia Carnazza; Cataldo Raffino; Nunziata Barbera
Journal:  J Forensic Sci       Date:  2022-04-28       Impact factor: 1.717

  1 in total

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