| Literature DB >> 31349441 |
Joanna Raczkowska1, Yurij Stetsyshyn2, Kamil Awsiuk3, Monika Brzychczy-Włoch4, Tomasz Gosiewski4, Benedykt Jany3, Ostap Lishchynskyi5, Yana Shymborska5, Svyatoslav Nastyshyn3, Andrzej Bernasik6, Halyna Ohar5, Franciszek Krok3, Dorota Ochońska4, Andrij Kostruba7, Andrzej Budkowski3.
Abstract
In the presented work "smart" antibacterial surfaces based on silver nanoparticles (AgNPs) embedded in temperature-responsive poly(di(ethylene glycol)methyl ether methacrylate) - (POEGMA188) as well as poly(4-vinylpyridine) - (P4VP) coatings attached to a glass surface were successfully prepared. The composition, thickness, morphology and wettability of the resulting coatings were analyzed using ToF-SIMS, XPS, EDX, ellipsometry, AFM, SEM and CA measurements, respectively. Temperature-switched killing of the bacteria was tested against Escherichia coli ATCC 25922 (representative of Gram-negative bacteria) and Staphylococcus aureus ATCC 25923 (representative of Gram-positive bacteria) at 4 and 37 °C. In general at 4 °C no significant difference was observed between the amounts of bacteria accounted on the grafted brush coatings and within the control sample. In contrast, at 37 °C almost no bacteria were visible for temperature-responsive coating with AgNPs, whereas the growth of bacteria remains not disturbed for "pure" coating, indicating strong temperature-dependent antibacterial properties of AgNPs integrated into brushes.Entities:
Keywords: Antibacterial; Grafted polymer brushes; Silver nanoparticles; Smart surface; Temperature-responsive
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Year: 2019 PMID： 31349441 DOI： 10.1016/j.msec.2019.109806
Source DB: PubMed Journal: Mater Sci Eng C Mater Biol Appl ISSN： 0928-4931 Impact factor: 7.328