| Literature DB >> 31345525 |
Abstract
Diagnosis of lymphocytic hypophysitis occurring in the peripartum period is based on clinical and neuroradiological data and does not require a biopsy. Its course is generally spontaneously favorable in terms of mass effect but may require the administration of corticosteroids or even transsphenoidal resection. The course of pituitary deficiencies is highly variable; some cases recover over time, whereas others persist indefinitely. Sheehan syndrome is very rare in developed countries. Because agalactia and amenorrhea are often neglected, the diagnosis is generally delayed. Diabetes insipidus occurring in late pregnancy is caused by the increased placental production of vasopressinase and disappears after delivery.Entities:
Keywords: Autoimmune; Diabetes insipidus; Hypophysitis; Hypopituitarism; Pregnancy; Sheehan syndrome
Mesh:
Year: 2019 PMID: 31345525 DOI: 10.1016/j.ecl.2019.05.005
Source DB: PubMed Journal: Endocrinol Metab Clin North Am ISSN: 0889-8529 Impact factor: 4.741