Literature DB >> 31343437

Pathogenesis and complications of chronic eye rubbing in ocular allergy.

Hadas Ben-Eli1,2, Nir Erdinest1, Abraham Solomon1.   

Abstract

PURPOSE OF REVIEW: To review the updated literature regarding eye rubbing complications and its association with ocular allergy disorders. RECENT
FINDINGS: Atopy and ocular allergy disorders, mainly vernal keratoconjunctivitis (VKC), are strongly associated with rubbing-related complications, most probably via itching and watery eye sensations that trigger the habit of chronic eye rubbing. Vigorous and prolonged rubbing may lead to establishment of corneal remodeling and ectatic disorders, such as keratoconus. Keratoconus development in rubbed eyes can be caused by mechanical mechanisms of corneal thinning and its loss of rigidity, by elevated temperature of the epithelium during rubbing, by increased intraocular pressure (IOP) because of distending forces, and by inflammatory molecules that may serve as a causal mediator between eye rubbing and keratoconus. Other eye rubbing complications include acute hydrops and perforation, IOP spikes, iris prolapse and iridoschisis rupture of lens capsule and IOL dislocation, and even posterior segment disorders, such as glaucomatous optic neuropathy, retinal detachment and extrusion of implanted silicone oil in the eye.
SUMMARY: Chronic eye rubbing in allergic eye diseases can lead to progression of keratoconus, and to other rare anterior and posterior segment complications. Strategies eliminating eye rubbing and its consequences are vital, mainly among at-risk populations, such as young children and individuals with allergic ocular disorders or corneal transplants.

Entities:  

Year:  2019        PMID: 31343437     DOI: 10.1097/ACI.0000000000000571

Source DB:  PubMed          Journal:  Curr Opin Allergy Clin Immunol        ISSN: 1473-6322


  13 in total

1.  The Sociodemographic and Risk Factors for Fuchs' Endothelial Dystrophy: A Nationwide, Matched Case-Control Study in Taiwan.

Authors:  Yuh-Shin Chang; Chung-Han Ho; Jhi-Joung Wang; Sung-Huei Tseng; Ren-Long Jan
Journal:  J Pers Med       Date:  2022-02-18

2.  Ovalbumin-Induced Allergic Inflammation Diminishes Cross-Linked Collagen Structures in an Experimental Rabbit Model of Corneal Cross-Linking.

Authors:  Zhongyang Zhao; Minghui Liang; Huan He; Xuemei Wang; Chengfang Zhu; Lan Li; Bin Liu; Rongrong Zong; Qifang Jin; Huping Wu; Wei Li; Zhirong Lin
Journal:  Front Med (Lausanne)       Date:  2022-05-26

3.  Absence of the c.169+50delTAAACAG mutation of SOD1 gene in a sample of keratoconus patients in Brazilian population.

Authors:  Alessandro Garcia Lopes; Gildásio Castello de Almeida Júnior; Ronan Marques Teixeira; Luiz Carlos de Mattos; Cinara Cássia Brandão de Mattos; Lilian Castiglioni
Journal:  BMC Res Notes       Date:  2020-07-09

4.  The Role of Atopy in the Choroidal Profile of Keratoconus Patients.

Authors:  Ana Filipa Moleiro; Ana Francisca Aires; Hélio Alves; João Viana Pinto; Ângela Carneiro; Fernando Falcão-Reis; Luís Figueira; João Pinheiro-Costa
Journal:  Clin Ophthalmol       Date:  2021-04-28

5.  A hospital-based study on clinical data, demographic data and visual function of keratoconus patients in Central China.

Authors:  Kaili Yang; Liyan Xu; Qi Fan; Yuwei Gu; Bo Zhang; Feiying Meng; Dongqing Zhao; Chenjiu Pang; Shengwei Ren
Journal:  Sci Rep       Date:  2021-04-06       Impact factor: 4.379

Review 6.  Tear Levels of Inflammatory Cytokines in Keratoconus: A Meta-Analysis of Case-Control and Cross-Sectional Studies.

Authors:  Huan Zhang; Xiupeng Cao; Ying Liu; Peihong Wang; Xuan Li
Journal:  Biomed Res Int       Date:  2021-09-30       Impact factor: 3.411

7.  Changes in Anterior and Posterior Corneal Elevation in Patients With Allergic Conjunctivitis.

Authors:  Qian Wang; Fei Yu; Ziqing Feng; Weihua Li; Naiyang Li; Xinyue Du; Xuan Zhao; Saiqun Li; Jin Yuan
Journal:  Front Med (Lausanne)       Date:  2021-11-24

8.  A Population-Based Study of Social Demographic Factors, Associated Diseases and Recurrent Corneal Erosion in Taiwan.

Authors:  Ren-Long Jan; Chung-Han Ho; Jhi-Joung Wang; Sung-Huei Tseng; Yuh-Shin Chang
Journal:  Front Public Health       Date:  2022-03-28

Review 9.  A Case-Cohort Study of Exfoliation Risk Factors and Literature Review.

Authors:  Ahmad M Mansour; Anastasios G P Konstas; Hana A Mansour; Abdul R Charbaji; Khalil M El Jawhari
Journal:  Middle East Afr J Ophthalmol       Date:  2021-04-30

10.  Association Between Atopic Keratoconjunctivitis and the Risk of Recurrent Corneal Erosion.

Authors:  Ren-Long Jan; Shih-Feng Weng; Jhi-Joung Wang; Sung-Huei Tseng; Yuh-Shin Chang
Journal:  Front Med (Lausanne)       Date:  2021-06-02
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