Literature DB >> 31342057

Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections.

Laura C Fanucchi1, Sharon L Walsh2, Alice C Thornton3, Paul A Nuzzo2, Michelle R Lofwall2.   

Abstract

In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days. CLINICAL TRIALS REGISTRATION: NCT03048643.
© The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  antibiotics; buprenorphine; endocarditis; injection-drug use; opioid-related disorders

Mesh：

Substances：

Year:  2020        PMID： 31342057      PMCID： PMC7931831          DOI： 10.1093/cid/ciz654

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  12 in total

1.  Proposed modifications to the Duke criteria for the diagnosis of infective endocarditis.

Authors:  J S Li; D J Sexton; N Mick; R Nettles; V G Fowler; T Ryan; T Bashore; G R Corey
Journal:  Clin Infect Dis       Date:  2000-04-03       Impact factor: 9.079

2.  Utility of the Time-Line Follow-Back to assess substance use among homeless adults.

Authors:  Jo Ann Y Sacks; Robert E Drake; Valerie F Williams; Steven M Banks; James M Herrell
Journal:  J Nerv Ment Dis       Date:  2003-03       Impact factor: 2.254

3.  Oral versus Intravenous Antibiotics for Bone and Joint Infection.

Authors:  Ho-Kwong Li; Ines Rombach; Rhea Zambellas; A Sarah Walker; Martin A McNally; Bridget L Atkins; Benjamin A Lipsky; Harriet C Hughes; Deepa Bose; Michelle Kümin; Claire Scarborough; Philippa C Matthews; Andrew J Brent; Jose Lomas; Roger Gundle; Mark Rogers; Adrian Taylor; Brian Angus; Ivor Byren; Anthony R Berendt; Simon Warren; Fiona E Fitzgerald; Damien J F Mack; Susan Hopkins; Jonathan Folb; Helen E Reynolds; Elinor Moore; Jocelyn Marshall; Neil Jenkins; Christopher E Moran; Andrew F Woodhouse; Samantha Stafford; R Andrew Seaton; Claire Vallance; Carolyn J Hemsley; Karen Bisnauthsing; Jonathan A T Sandoe; Ila Aggarwal; Simon C Ellis; Deborah J Bunn; Rebecca K Sutherland; Gavin Barlow; Cushla Cooper; Claudia Geue; Nicola McMeekin; Andrew H Briggs; Parham Sendi; Elham Khatamzas; Tri Wangrangsimakul; T H Nicholas Wong; Lucinda K Barrett; Abtin Alvand; C Fraser Old; Jennifer Bostock; John Paul; Graham Cooke; Guy E Thwaites; Philip Bejon; Matthew Scarborough
Journal:  N Engl J Med       Date:  2019-01-31       Impact factor: 91.245

4.  Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis.

Authors:  Kasper Iversen; Nikolaj Ihlemann; Sabine U Gill; Trine Madsen; Hanne Elming; Kaare T Jensen; Niels E Bruun; Dan E Høfsten; Kurt Fursted; Jens J Christensen; Martin Schultz; Christine F Klein; Emil L Fosbøll; Flemming Rosenvinge; Henrik C Schønheyder; Lars Køber; Christian Torp-Pedersen; Jannik Helweg-Larsen; Niels Tønder; Claus Moser; Henning Bundgaard
Journal:  N Engl J Med       Date:  2018-08-28       Impact factor: 91.245

5.  Integrated outpatient treatment of opioid use disorder and injection-related infections: A description of a new care model.

Authors:  Laura C Fanucchi; Sharon L Walsh; Alice C Thornton; Michelle R Lofwall
Journal:  Prev Med       Date:  2019-06-26       Impact factor: 4.018

6.  In-hospital illicit drug use, substance use disorders, and acceptance of residential treatment in a prospective pilot needs assessment of hospitalized adults with severe infections from injecting drugs.

Authors:  Laura C Fanucchi; Michelle R Lofwall; Paul A Nuzzo; Sharon L Walsh
Journal:  J Subst Abuse Treat       Date:  2018-06-22

7.  A 9-Point Risk Assessment for Patients Who Inject Drugs and Require Intravenous Antibiotics: Focusing Inpatient Resources on Patients at Greatest Risk of Ongoing Drug Use.

Authors:  Ellen F Eaton; Ronnie E Mathews; Peter S Lane; Cayce S Paddock; Jorge Martin Rodriguez; Benjamin B Taylor; Michael S Saag; Meredith L Kilgore; Rachael A Lee
Journal:  Clin Infect Dis       Date:  2019-03-05       Impact factor: 9.079

8.  Hospitalizations for Endocarditis and Associated Health Care Costs Among Persons with Diagnosed Drug Dependence - North Carolina, 2010-2015.

Authors:  Aaron T Fleischauer; Laura Ruhl; Sarah Rhea; Erin Barnes
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2017-06-09       Impact factor: 17.586

9.  Invasive Methicillin-Resistant Staphylococcus aureus Infections Among Persons Who Inject Drugs - Six Sites, 2005-2016.

Authors:  Kelly A Jackson; Michele K Bohm; John T Brooks; Alice Asher; Joelle Nadle; Wendy M Bamberg; Sue Petit; Susan M Ray; Lee H Harrison; Ruth Lynfield; Ghinwa Dumyati; William Schaffner; John M Townes; Isaac See
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2018-06-08       Impact factor: 17.586

Review 10.  Outpatient Parenteral Antimicrobial Therapy Among People Who Inject Drugs: A Review of the Literature.

Authors:  Joji Suzuki; Jennifer Johnson; Mary Montgomery; Margaret Hayden; Christin Price
Journal:  Open Forum Infect Dis       Date:  2018-08-07       Impact factor: 3.835
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  24 in total

1.  Improving Outcomes for People With Injection Drug-related Endocarditis: Are Medications for Opioid Use Disorder Enough?

Authors:  Simeon D Kimmel; Carlos Del Rio
Journal:  J Addict Med       Date:  2020 Jul/Aug       Impact factor: 3.702

2.  The Opioid Crisis and the Inpatient Floor: Considering Injection Drug Use in the Management of Infective Endocarditis and Acute Pain.

Authors:  Lauren M Mitchell; Aimee Milliken; Mary W Montgomery; Steve K Singh; Joji Suzuki
Journal:  Harv Rev Psychiatry       Date:  2020 Sep/Oct       Impact factor: 3.732

3.  Opioid agonist treatment and risk of death or rehospitalization following injection drug use-associated bacterial and fungal infections: A cohort study in New South Wales, Australia.

Authors:  Thomas D Brothers; Dan Lewer; Nicola Jones; Samantha Colledge-Frisby; Michael Farrell; Matthew Hickman; Duncan Webster; Andrew Hayward; Louisa Degenhardt
Journal:  PLoS Med       Date:  2022-07-19       Impact factor: 11.613

4.  Medication for opioid use disorder at hospital discharge is not associated with intravenous antibiotic completion in post-acute care facilities.

Authors:  Edward C Traver; Patrick R Ching; Shivakumar Narayanan
Journal:  Ther Adv Infect Dis       Date:  2022-06-21

5.  Design and protocol of the Buprenorphine plus Outpatient Parenteral Antimicrobial Therapy (B-OPAT) study: a randomized clinical trial of integrated outpatient treatment of opioid use disorder and severe, injection-related infections.

Authors:  Laura C Fanucchi; Sean M Murphy; Hilary Surratt; Shashi N Kapadia; Sharon L Walsh; James A Grubbs; Alice C Thornton; Paul Nuzzo; Michelle R Lofwall
Journal:  Ther Adv Infect Dis       Date:  2022-07-11

6.  Feasibility and Safety of Outpatient Parenteral Antimicrobial Therapy in Conjunction With Addiction Treatment for People Who Inject Drugs.

Authors:  Christin N Price; Daniel A Solomon; Jennifer A Johnson; Mary W Montgomery; Bianca Martin; Joji Suzuki
Journal:  J Infect Dis       Date:  2020-09-02       Impact factor: 5.226

Review 7.  Infective Endocarditis in Persons Who Use Drugs: Epidemiology, Current Management, and Emerging Treatments.

Authors:  Asher Schranz; Joshua A Barocas
Journal:  Infect Dis Clin North Am       Date:  2020-09       Impact factor: 5.982

8.  A qualitative assessment of discharge against medical advice among patients hospitalized for injection-related bacterial infections in West Virginia.

Authors:  R A Pollini; C E Paquette; T Drvar; P Marshalek; M Ang-Rabanes; J Feinberg; M W Haut
Journal:  Int J Drug Policy       Date:  2021-03-23

Review 9.  Soft Tissue, Bone, and Joint Infections in People Who Inject Drugs.

Authors:  Carlos S Saldana; Darshali A Vyas; Alysse G Wurcel
Journal:  Infect Dis Clin North Am       Date:  2020-09       Impact factor: 5.982

10.  Evaluation of Bundled Interventions for Patients With Opioid Use Disorder Experiencing Homelessness Receiving Extended Antibiotics for Severe Infection.

Authors:  Alison M Beieler; Jared W Klein; Elenore Bhatraju; Matthew Iles-Shih; Leslie Enzian; Shireesha Dhanireddy
Journal:  Open Forum Infect Dis       Date:  2021-05-29       Impact factor: 3.835
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