| Literature DB >> 31335372 |
Ryan Avery1, Imo Ebong2, Rinku Skaria3, Kevin Day1, Christopher Miller1, Elizabeth Juneman2, Isabel Oliva4, Mark Friedman2, Simon Maltais5, Zain Khalpey3.
Abstract
Accurate right ventricle functional analysis prior to mechanical circulatory support continues to be valuable for preoperative stratification of patients at risk for developing right ventricular (RV) failure. While cardiac magnetic resonance imaging (CMR) remains the gold standard, CMR is limited by availability and patient-specific contraindications. Further investigation of other imaging modalities would be beneficial as it may serve as a surrogate to identifying RV systolic dysfunction. A single-center, retrospective study including 29 patients with advanced heart failure was performed. All patients underwent ventricular functional analysis with both CMR and echocardiography, and 19 patients underwent right heart catheterization. Predictability with multimodal assessment of RV function was determined using logistic regression methods. Of the 29 participants, 10 had severe RV dysfunction. Tricuspid annular plane of systolic excursion was a modest predictor of RV dysfunction with odd ratio (OR) of 0.07 (0.01-0.72) and c-statistic of 0.79. Invasive hemodynamic measurement of cardiac index by thermodilution method was also predictive of RV dysfunction but failed to reach statistical significance (OR of 0.03, <0.001-1.28) with c-statistic of 0.83. The role of invasive hemodynamic data in predicting RV function compared with CMR should be further explored among patients with advanced heart failure.Entities:
Mesh:
Year: 2020 PMID: 31335372 DOI: 10.1097/MAT.0000000000001046
Source DB: PubMed Journal: ASAIO J ISSN: 1058-2916 Impact factor: 2.872