P Divya Kumari1, Shilpa M Shenoy2, Shahnawaz Khijmatgar1, Avidyuti Chowdhury3, Edward Lynch4, Chitta R Chowdhury1. 1. Department of Oral Biology and Genomic Studies, A.B.Shetty Memorial Institute of Dental Sciences, Nitte Deemed to be University, Deralakatte, Mangalore, Karnataka, India. 2. Central Research Laboratory, K.S.Hegde Medical Academy, Nitte Deemed to be University. Deralakatte, Mangalore, Karnataka, India. 3. Kings College London, Global Child Health Fund, England, UK. 4. Professor & Head of Dentistry,Warwick Dentistry, Warwick Medical School, Coventry, CV4 7AL, UK.
Abstract
BACKGROUND: The antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta indica (Neem) on Streptococcus mutans was carried out. MATERIALS AND METHODS: The study was carried out by using the agar diffusion method to determine the antibacterial property of ART materials (ART-I and ART-II). The zone of inhibition was tabulated, and the data was statistically analyzed using the student t-test. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) of the ethanolic extract of Neem were recorded. RESULTS: The MIC and MBC of the mixture of the ethanolic extract of Neem was 3.13% and 12.5% respectively. The zone of inhibition of ART-I and ART-II was 11.81 mm and 11.97 mm respectively. Significant differences were observed between these two ART materials (P = 0,08). CONCLUSION: Both the new ART materials i.e. ART-I and ART-II have considerable antibacterial activity against S. mutans.
BACKGROUND: The antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta indica (Neem) on Streptococcus mutans was carried out. MATERIALS AND METHODS: The study was carried out by using the agar diffusion method to determine the antibacterial property of ART materials (ART-I and ART-II). The zone of inhibition was tabulated, and the data was statistically analyzed using the student t-test. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) of the ethanolic extract of Neem were recorded. RESULTS: The MIC and MBC of the mixture of the ethanolic extract of Neem was 3.13% and 12.5% respectively. The zone of inhibition of ART-I and ART-II was 11.81 mm and 11.97 mm respectively. Significant differences were observed between these two ART materials (P = 0,08). CONCLUSION: Both the new ART materials i.e. ART-I and ART-II have considerable antibacterial activity against S. mutans.
Authors: Cristiane da Mata; Patrick F Allen; Michael Cronin; Denis O'Mahony; Gerald McKenna; Noel Woods Journal: Community Dent Oral Epidemiol Date: 2013-08-19 Impact factor: 3.383
Authors: P Divya Kumari; A Veena Shetty; Shahnawaz Khijmatgar; Avidyuti Chowdhury; Edward Lynch; Chitta R Chowdhury Journal: J Oral Biol Craniofac Res Date: 2018-08-28
Authors: Sina Klai; Markus Altenburger; Bettina Spitzmüller; Annette Anderson; Elmar Hellwig; Ali Al-Ahmad Journal: ScientificWorldJournal Date: 2014-03-23