Manuel Méndez Bailón1, Jose María Cepeda Rodrigo2, Noel Lorenzo-Villalba3, Jose Manuel Cerqueiro4, Jose Curbelo García5, Elpidio Calvo Manuel6, Francisco Javier Martín-Sánchez7, Ramon Bover Freire8, Pilar Cubo Romano9, Luis Manzano Espinosa10, Jose Carlos Arévalo-Lorido11, Jose Manuel Casas Rojo9, Juan Torres Macho9. 1. Internal Medicine Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IDISSC), Facultad de Medicina, Universidad Complutense, Avda. Prof. Martin Lago S/N, 28040, Madrid, Spain. manuel.mendez@salud.madrid.org. 2. Internal Medicine Department, Hospital Vega Baja, Orihuela, Spain. 3. Internal Medicine Department, Hôpitaux Universitaires de Strasbourg, Strasbourg, France. 4. Internal Medicine Department, Hospital Universitario Lucus Augusti, Lugo, Spain. 5. Internal Medicine Department, Hospital Universitario La Princesa, Madrid, Spain. 6. Internal Medicine Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IDISSC), Facultad de Medicina, Universidad Complutense, Avda. Prof. Martin Lago S/N, 28040, Madrid, Spain. 7. Emergency Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Universidad Complutense de Madrid, Madrid, Spain. 8. Cardiology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Universidad Complutense de Madrid, Madrid, Spain. 9. Internal Medicine Department, Hospital Universitario Infanta Cristina, Parla, Madrid, Spain. 10. Internal Medicine Department, Hospital Universitario Ramón y Cajal, Madrid, Spain. 11. Internal Medicine Department, Hospital de Zafra, Zafra, Badajoz, Spain.
Abstract
INTRODUCTION AND OBJECTIVES:Pulmonary congestion (PC) is associated with an increased risk of hospitalization and death in patients with heart failure (HF). Lung ultrasound has shown to be highly sensitive for detecting PC in HF. The aim of this study is to evaluate whether lung ultrasound-guided therapy improves 6-month outcomes in patients with HF compared with conventional treatment. MATERIALS AND METHODS: Randomized, multicenter, single-blind clinical trial in patients discharged from Internal Medicine Departments after hospitalization for decompensated HF. Participants will be assigned 1:1 to receive treatment guided according to the presence of lung ultrasound signs of congestion (semi-quantitative evaluation of B lines and the presence of pleural effusion) versus clinical assessment of congestion. The primary outcome is the combination of cardiovascular death and readmission for HF at 6 months. CONCLUSIONS: The results of this study will provide more evidence about the impact of lung ultrasound on treatment monitoring in patients with chronic HF.
RCT Entities:
INTRODUCTION AND OBJECTIVES: Pulmonary congestion (PC) is associated with an increased risk of hospitalization and death in patients with heart failure (HF). Lung ultrasound has shown to be highly sensitive for detecting PC in HF. The aim of this study is to evaluate whether lung ultrasound-guided therapy improves 6-month outcomes in patients with HF compared with conventional treatment. MATERIALS AND METHODS: Randomized, multicenter, single-blind clinical trial in patients discharged from Internal Medicine Departments after hospitalization for decompensated HF. Participants will be assigned 1:1 to receive treatment guided according to the presence of lung ultrasound signs of congestion (semi-quantitative evaluation of B lines and the presence of pleural effusion) versus clinical assessment of congestion. The primary outcome is the combination of cardiovascular death and readmission for HF at 6 months. CONCLUSIONS: The results of this study will provide more evidence about the impact of lung ultrasound on treatment monitoring in patients with chronic HF.
Authors: Micah L A Heldeweg; Lian Vermue; Max Kant; Michelle Brouwer; Armand R J Girbes; Mark E Haaksma; Leo M A Heunks; Amne Mousa; Jasper M Smit; Thomas W Smits; Frederique Paulus; Johannes C F Ket; Marcus J Schultz; Pieter Roel Tuinman Journal: Ultrasound J Date: 2022-01-10
Authors: Juan Torres-Macho; Jose Manuel Cerqueiro-González; Jose Carlos Arévalo-Lorido; Pau Llácer-Iborra; Jose María Cepeda-Rodrigo; Pilar Cubo-Romano; Jose Manuel Casas-Rojo; Raúl Ruiz-Ortega; Luis Manzano-Espinosa; Noel Lorenzo-Villalba; Manuel Méndez-Bailón Journal: J Clin Med Date: 2022-08-22 Impact factor: 4.964