Literature DB >> 31332612

Clinical impact of periodontal disease on postoperative complications in gastrointestinal cancer patients.

Mao Nishikawa1, Michitaka Honda2,3, Ryosuke Kimura1, Ayaka Kobayashi1, Yuji Yamaguchi1, Hiroshi Kobayashi4,5, Hidetaka Kawamura4,5, Yujiro Nakayama4,5, Yukitoshi Todate4,5, Yoshinao Takano5, Hisashi Yamaguchi4, Koichi Hamada4, Susumu Iketani1, Ichiro Seto1, Kanichi Seto1.   

Abstract

BACKGROUND: The effectiveness of perioperative oral management in gastrointestinal surgery remains unclear. To elucidate the clinical significance of oral care, we investigated the relationship between the oral environment and postoperative infectious complications (POICs) in patients undergoing gastrointestinal surgery.
METHODS: This was a single-institute and historical cohort study of 341 patients. The participants were isolated from consecutive patients undergoing planned radical resection for gastrointestinal carcinoma from January 2016 to June 2017. Dentists assessed the oral environment for periodontal disease, hygiene status, dry mouth, fur on tongue, and tooth stumps. All patients received scaling and tooth brushing instructions. A stepwise logistic regression analysis was conducted to identify risk factors for POICs among the different oral statuses.
RESULTS: The surgical procedures performed were gastrectomy in 123 (36.1%), colorectal resection in 185 (54.2%), and pancreatoduodenectomy or others in 38 (11.1%). POICs occurred in 48 patients (14.1%), including deep organ space infection in 20, surgical site infection in 11, anastomotic leakage in 5, urinary tract infection in 4, pneumonia in 2, and others in 6. After adjusting for confounding factors, periodontal disease was isolated as an independent risk factor for POICs (odds ratio 2.091, p = 0.037, 95% confidence interval 1.045-4.183). Other variables of oral environment such as hygiene status, dry mouth, fur on tongue, and tooth stumps did not have a significant impact on POICs.
CONCLUSIONS: Periodontal disease is a risk factor for infectious complications after gastrointestinal surgery.

Entities:  

Keywords:  Infectious complication; Oncological surgery; Periodontal disease; Perioperative oral management

Mesh:

Year:  2019        PMID: 31332612     DOI: 10.1007/s10147-019-01513-y

Source DB:  PubMed          Journal:  Int J Clin Oncol        ISSN: 1341-9625            Impact factor:   3.402


  31 in total

1.  Oral care and pneumonia. Oral Care Working Group.

Authors:  T Yoneyama; M Yoshida; T Matsui; H Sasaki
Journal:  Lancet       Date:  1999-08-07       Impact factor: 79.321

Review 2.  Periodontal health status and bacteraemia from daily oral activities: systematic review/meta-analysis.

Authors:  Inmaculada Tomás; Pedro Diz; Aurelio Tobías; Crispian Scully; Nikolaos Donos
Journal:  J Clin Periodontol       Date:  2011-09-15       Impact factor: 8.728

3.  Association among rheumatoid arthritis, oral hygiene, and periodontitis.

Authors:  N Pischon; T Pischon; J Kröger; E Gülmez; B-M Kleber; J-P Bernimoulin; H Landau; P-G Brinkmann; P Schlattmann; J Zernicke; F Buttgereit; J Detert
Journal:  J Periodontol       Date:  2008-06       Impact factor: 6.993

Review 4.  Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis.

Authors:  Linda L Humphrey; Rongwei Fu; David I Buckley; Michele Freeman; Mark Helfand
Journal:  J Gen Intern Med       Date:  2008-09-20       Impact factor: 5.128

5.  Postoperative pneumonia-prevention program for the inpatient surgical ward.

Authors:  Sherry M Wren; Molinda Martin; Jung K Yoon; Fritz Bech
Journal:  J Am Coll Surg       Date:  2010-04       Impact factor: 6.113

6.  Toxicity and response criteria of the Eastern Cooperative Oncology Group.

Authors:  M M Oken; R H Creech; D C Tormey; J Horton; T E Davis; E T McFadden; P P Carbone
Journal:  Am J Clin Oncol       Date:  1982-12       Impact factor: 2.339

Review 7.  The pathobiology of periodontal diseases may affect systemic diseases: inversion of a paradigm.

Authors:  R C Page
Journal:  Ann Periodontol       Date:  1998-07

8.  Impact of improvement in preoperative oral health on nosocomial pneumonia in a group of cardiac surgery patients: a single arm prospective intervention study.

Authors:  Eduardo H Bergan; Bernardo R Tura; Cristiane C Lamas
Journal:  Intensive Care Med       Date:  2013-08-07       Impact factor: 17.440

9.  Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group.

Authors:  Walter Wilson; Kathryn A Taubert; Michael Gewitz; Peter B Lockhart; Larry M Baddour; Matthew Levison; Ann Bolger; Christopher H Cabell; Masato Takahashi; Robert S Baltimore; Jane W Newburger; Brian L Strom; Lloyd Y Tani; Michael Gerber; Robert O Bonow; Thomas Pallasch; Stanford T Shulman; Anne H Rowley; Jane C Burns; Patricia Ferrieri; Timothy Gardner; David Goff; David T Durack
Journal:  Circulation       Date:  2007-04-19       Impact factor: 29.690

Review 10.  Effects of diabetes mellitus on periodontal and peri-implant conditions: update on associations and risks.

Authors:  Giovanni E Salvi; Barbara Carollo-Bittel; Niklaus P Lang
Journal:  J Clin Periodontol       Date:  2008-09       Impact factor: 8.728

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  5 in total

1.  The pathological oral cavity as a preventable source of postoperative pneumonia in thoracic surgery: a prospective observational study.

Authors:  Till Ploenes; Arianne Pollok; Karl-Heinz Jöckel; Sandra Kampe; Kaid Darwiche; Christian Taube; Jan Buer; Clemens Aigner
Journal:  J Thorac Dis       Date:  2022-04       Impact factor: 3.005

2.  Pneumonia prevention effects of perioperative oral management in approximately 25,000 patients following cancer surgery.

Authors:  Yasuhiro Kurasawa; Yutaka Maruoka; Hideki Sekiya; Akihide Negishi; Hitoshi Mukohyama; Shiro Shigematsu; Jumpei Sugizaki; Kazunari Karakida; Masaru Ohashi; Masayuki Ueno; Yukihiro Michiwaki
Journal:  Clin Exp Dent Res       Date:  2019-12-17

3.  The bacterial association with oral cavity and intra-abdominal abscess after gastrectomy.

Authors:  Mao Nishikawa; Michitaka Honda; Ryosuke Kimura; Ayaka Kobayashi; Yuji Yamaguchi; Soshi Hori; Hiroshi Kobayashi; Mitsuru Waragai; Hidetaka Kawamura; Yujiro Nakayama; Yukitoshi Todate; Yoshinao Takano; Hisashi Yamaguchi; Koichi Hamada; Susumu Iketani; Ichiro Seto; Yuichi Izumi; Kanichi Seto
Journal:  PLoS One       Date:  2020-11-09       Impact factor: 3.240

4.  Effects of periodontitis on postoperative pneumonia in patients with lung and esophageal cancer.

Authors:  Chunling Jia; Yijun Luan; Xibo Li; Xiaoying Zhang; Cuirong Li
Journal:  Thorac Cancer       Date:  2021-01-24       Impact factor: 3.500

5.  Factors That Influence the Judgment of Oral Management Necessity in Preoperative Oral Screening.

Authors:  Nanami Kai; Yoko Tsukamoto; Kaoru Urabe; Asuka Tani; Yuko Inai; Asako Okadome; Haruhiko Kashiwazaki; Shinsuke Mizutani; Naohisa Wada
Journal:  Int J Environ Res Public Health       Date:  2021-11-22       Impact factor: 3.390

  5 in total

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