Christoph Klingelhöffer1, Annegret Obst2, Tobias Ettl2, Johannes Meier2, Steffen Müller2, Torsten Reichert2, Gerrit Spanier2. 1. Department of Cranio-Maxillofacial Surgery, Hospital of the University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany. Electronic address: christoph.klingelhoeffer@ukr.de. 2. Department of Cranio-Maxillofacial Surgery, Hospital of the University of Regensburg, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany.
Abstract
OBJECTIVES: The aim of this retrospective study was to analyze the early postoperative swallowing outcome in oral cancer patients considering risk factors and localization. MATERIALS AND METHODS: Four hundred patients with primary cases of oral cancer were included. Tumors' locations were categorized into four main groups (central, lateral, anterior and posterior). Swallowing function was evaluated at day 7 after surgery. RESULTS: Ninety-eight percent (393/400) of the patients had a swallowing impairment including 41 (10.2%) patients who were unable to swallow. Strong risk factors with p values of 0.001 were tumor size, nodal stage, tracheotomy, insufficient dental status and reconstruction with a flap. The inability to swallow was increased at T1 und T2 patients, if they were reconstructed with a flap compared to patients who had a primary wound closure (p = 0.04). Decreased swallowing function was determined if the tumor was located central (OR = 1.8; p = 0.141) and additionally posterior (OR = 5.8; p = 0.110). Inability to swallow, even at that early point in time, (p = 0.001) was as significant as tumor size (p = 0.009) and nodal stage (p = 0.020), referring to overall survival. CONCLUSION: The impact of early dysphagia should not be underestimated. By considering swallowing impairment at the primary therapy patients can profit concerning survival and comorbidity.
OBJECTIVES: The aim of this retrospective study was to analyze the early postoperative swallowing outcome in oral cancerpatients considering risk factors and localization. MATERIALS AND METHODS: Four hundred patients with primary cases of oral cancer were included. Tumors' locations were categorized into four main groups (central, lateral, anterior and posterior). Swallowing function was evaluated at day 7 after surgery. RESULTS: Ninety-eight percent (393/400) of the patients had a swallowing impairment including 41 (10.2%) patients who were unable to swallow. Strong risk factors with p values of 0.001 were tumor size, nodal stage, tracheotomy, insufficient dental status and reconstruction with a flap. The inability to swallow was increased at T1 und T2 patients, if they were reconstructed with a flap compared to patients who had a primary wound closure (p = 0.04). Decreased swallowing function was determined if the tumor was located central (OR = 1.8; p = 0.141) and additionally posterior (OR = 5.8; p = 0.110). Inability to swallow, even at that early point in time, (p = 0.001) was as significant as tumor size (p = 0.009) and nodal stage (p = 0.020), referring to overall survival. CONCLUSION: The impact of early dysphagia should not be underestimated. By considering swallowing impairment at the primary therapy patients can profit concerning survival and comorbidity.
Authors: Uta Lehner; Eugen Zaretsky; Almut Goeze; Laura Wermter; Boris A Stuck; Richard Birk; Andreas Neff; Ingo Fischer; Shahram Ghanaati; Robert Sader; Christiane Hey Journal: HNO Date: 2022-02-04 Impact factor: 1.330
Authors: Doke J M Buurman; Anna C H Willemsen; Caroline M Speksnijder; Laura W J Baijens; Ann Hoeben; Frank J P Hoebers; Peter Kessler; Annemie M W J Schols Journal: Support Care Cancer Date: 2022-03-12 Impact factor: 3.359