| Literature DB >> 31331487 |
Yun Chen1, Liang Liu2, Ronghua Ni2, Weixian Zhou2.
Abstract
HER2-positive breast cancer is a particularly aggressive type of breast cancer. Indication of HER2 positivity is essential for its treatment. In addition to a few FDA-approved methods such as immunohistochemical (IHC) detection of HER2 protein expression and in situ hybridization (ISH) assessment of HER2 gene amplification, several novel methods have been developed for HER2 testing in recent years. This chapter provides an overview of HER2 testing with emphasis on those new methods.Entities:
Keywords: Breast cancer; FISH; Gene; HER2 testing; IHC; Methods in development; Protein
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Year: 2019 PMID: 31331487 DOI: 10.1016/bs.acc.2019.03.004
Source DB: PubMed Journal: Adv Clin Chem ISSN: 0065-2423 Impact factor: 5.394