| Literature DB >> 3132953 |
R A Weiss1, P R Clapham, J N Weber, D Whitby, R S Tedder, T O'Connor, S Chamaret, L Montagnier.
Abstract
The neutralization properties of three independent HIV-2 isolates were examined in comparison with four diverse HIV-1 strains. Human sera containing antibodies specific to HIV-2 can cross-neutralize HIV-1. By contrast, HIV-1 sera are group-specific and have no neutralizing effect on HIV-2. Therefore, HIV-2 antigens may be important components for the development of broadly cross-protective AIDS vaccines.Entities:
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Year: 1988 PMID: 3132953 DOI: 10.1097/00002030-198804000-00004
Source DB: PubMed Journal: AIDS ISSN: 0269-9370 Impact factor: 4.177