Literature DB >> 31329359

Controlled donation after circulatory death up to 80 years for liver transplantation: Pushing the limit again.

Pedro A Cascales-Campos1,2, David Ferreras1,2, Felipe Alconchel1,2, Beatriz Febrero1,2, Mario Royo-Villanova2,3, María Martínez2,3, José M Rodríguez1,2, Juan Á Fernández-Hernández1,2, Antonio Ríos1,2, José A Pons2,4, Francisco Sánchez-Bueno1,2, Ricardo Robles1,2, Enrique Martínez-Barba2,5, Laura Martínez-Alarcón1,2, Pascual Parrilla1,2, Pablo Ramírez1,2.   

Abstract

Our main objective was to compare liver transplant (LT) results between donation after circulatory death (DCD) and donation after brainstem death (DBD) in our hospital and to analyze, within the DCD group, the influence of age on the results obtained with DCD donors aged >70 years and up to 80 years. All DCD-LTs performed were analyzed prospectively. The results of the DCD group were compared with those of a control group who received a DBD-LT immediately after each DCD-LT. Later, the results obtained within the DCD group were analyzed according to the age of the donors, considering 2 subgroups with a cut-off point at 70 years. Survival results for LT with DCD and super rapid recovery were not inferior to those obtained in a similar group of patients transplanted with DBD livers. However, the cost of DCD was a higher rate of biliary complications, including ischemic cholangiopathy. Donor age was not a negative factor.
© 2019 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research/practice; donors and donation; donors and donation: deceased; donors and donation: donation after brain death (DBD); donors and donation: donation after circulatory death (DCD); donors and donation: extended criteria; health services and outcomes research; liver transplantation/hepatology; organ procurement and allocation; organ transplantation in general

Mesh:

Year:  2019        PMID: 31329359     DOI: 10.1111/ajt.15537

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  3 in total

1.  Donation after circulatory death liver transplantation: consensus statements from the Spanish Liver Transplantation Society.

Authors:  Amelia J Hessheimer; Mikel Gastaca; Eduardo Miñambres; Jordi Colmenero; Constantino Fondevila
Journal:  Transpl Int       Date:  2020-05-15       Impact factor: 3.782

2.  CRISPR-Mediated Genomic Addition to CPS1 Deficient iPSCs is Insufficient to Restore Nitrogen Homeostasis.

Authors:  Matthew Nitzahn; Brian Truong; Suhail Khoja; Agustin Vega-Crespo; Colleen Le; Adam Eliav; Georgios Makris; April D Pyle; Johannes Häberle; Gerald S Lipshutz
Journal:  Yale J Biol Med       Date:  2021-12-29

3.  The New Age of Organ Donation-What Factors Have an Influence on the Attitude of Older People? An Attitudinal Survey in Southeastern Spain.

Authors:  Beatriz Febrero; Javier Almela-Baeza; Inmaculada Ros-Madrid; José Alfonso Arias; Juan José Ruiz-Manzanera; María Isabel Jiménez-Mascuñán; Pablo Ramírez
Journal:  Int J Environ Res Public Health       Date:  2022-07-12       Impact factor: 4.614

  3 in total

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