| Literature DB >> 31329359 |
Pedro A Cascales-Campos1,2, David Ferreras1,2, Felipe Alconchel1,2, Beatriz Febrero1,2, Mario Royo-Villanova2,3, María Martínez2,3, José M Rodríguez1,2, Juan Á Fernández-Hernández1,2, Antonio Ríos1,2, José A Pons2,4, Francisco Sánchez-Bueno1,2, Ricardo Robles1,2, Enrique Martínez-Barba2,5, Laura Martínez-Alarcón1,2, Pascual Parrilla1,2, Pablo Ramírez1,2.
Abstract
Our main objective was to compare liver transplant (LT) results between donation after circulatory death (DCD) and donation after brainstem death (DBD) in our hospital and to analyze, within the DCD group, the influence of age on the results obtained with DCD donors aged >70 years and up to 80 years. All DCD-LTs performed were analyzed prospectively. The results of the DCD group were compared with those of a control group who received a DBD-LT immediately after each DCD-LT. Later, the results obtained within the DCD group were analyzed according to the age of the donors, considering 2 subgroups with a cut-off point at 70 years. Survival results for LT with DCD and super rapid recovery were not inferior to those obtained in a similar group of patients transplanted with DBD livers. However, the cost of DCD was a higher rate of biliary complications, including ischemic cholangiopathy. Donor age was not a negative factor.Entities:
Keywords: clinical research/practice; donors and donation; donors and donation: deceased; donors and donation: donation after brain death (DBD); donors and donation: donation after circulatory death (DCD); donors and donation: extended criteria; health services and outcomes research; liver transplantation/hepatology; organ procurement and allocation; organ transplantation in general
Mesh:
Year: 2019 PMID: 31329359 DOI: 10.1111/ajt.15537
Source DB: PubMed Journal: Am J Transplant ISSN: 1600-6135 Impact factor: 8.086