Literature DB >> 31329329

Quantitative proteomic analyses in blood: A window to human health and disease.

Kelly Whittaker1, Rob Burgess1, Valerie Jones1, Yanqing Yang2, Weifan Zhou2, Shuhong Luo1,2,3, Jarad Wilson1, Ruo-Pan Huang1,2,3,4,5.   

Abstract

This review discusses how the measurement of proteins in blood and its components via quantitative proteomics analyses can inform health status. Various external and internal factors such as environmental conditions, genetic background, nutrition, diet, and lifestyle, chronic pathological conditions, disease state, or therapeutic intervention will be investigated and their effects on the protein profile will be shown. The resulting changes to ones' health and how this protein expression information can be used in early screening/diagnostic applications, drug discovery, precision treatment, patient management, and monitoring overall health status will also be presented. ©2019 Society for Leukocyte Biology.

Entities:  

Keywords:  IL-6; Parkinson's Disease; breast cancer; colorectal cancer; cytokine; lupus; obesity; prostate cancer; proteomics

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Year:  2019        PMID： 31329329     DOI： 10.1002/JLB.MR1118-440R

Source DB:  PubMed          Journal:  J Leukoc Biol        ISSN： 0741-5400            Impact factor:   4.962


  3 in total

1.  Quantitative Plasma Proteomics to Identify Candidate Biomarkers of Relapse in Pediatric/Adolescent Hodgkin Lymphoma.

Authors:  Ombretta Repetto; Laura Caggiari; Mariangela De Zorzi; Caterina Elia; Lara Mussolin; Salvatore Buffardi; Marta Pillon; Paola Muggeo; Tommaso Casini; Agostino Steffan; Christine Mauz-Körholz; Maurizio Mascarin; Valli De Re
Journal:  Int J Mol Sci       Date:  2022-08-31       Impact factor: 6.208

2.  Plasma protein-based signature predicts distant metastasis and induction chemotherapy benefit in Nasopharyngeal Carcinoma.

Authors:  Yelin Liang; Junyan Li; Qian Li; Linglong Tang; Lei Chen; Yanping Mao; Qingmei He; Xiaojing Yang; Yuan Lei; Xiaohong Hong; Yin Zhao; Shiwei He; Ying Guo; Yaqin Wang; Panpan Zhang; Na Liu; Yingqin Li; Jun Ma
Journal:  Theranostics       Date:  2020-08-01       Impact factor: 11.556

3.  High-throughput proteomics of breast cancer interstitial fluid: identification of tumor subtype-specific serologically relevant biomarkers.

Authors:  Thilde Terkelsen; Maria Pernemalm; Pavel Gromov; Anna-Lise Børresen-Dale; Anders Krogh; Vilde D Haakensen; Janne Lethiö; Elena Papaleo; Irina Gromova
Journal:  Mol Oncol       Date:  2021-01-04       Impact factor: 7.449
  3 in total

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