Literature DB >> 3132874

Development of acidosis in human beings during closed-chest and open-chest CPR.

P L Henneman1, J E Gruber, J A Marx.   

Abstract

We studied the development of acidosis, as measured by blood gases, in a convenience sample of 16 patients undergoing five minutes of closed-chest CPR (CC-CPR) followed by five minutes of open-chest CPR (OC-CPR). To eliminate the influence of variable pCO2 on serum pH, all blood gas values were adjusted to a pCO2 of 40 mm Hg. Adjusted pH fell a mean of 0.09 U (SEM +/- 0.03, P = .02) with five minutes of CC-CPR and then 0.05 U (SEM +/- 0.02, P = .05) with five minutes of OC-CPR. The decline in adjusted pH during CC-CPR was statistically comparable to the decline that occurred during OC-CPR. The development of acidosis as measured by blood gases does not appear to be significantly different for patients undergoing five minutes of CC-CPR versus five minutes of OC-CPR when OC-CPR follows CC-CPR.

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Year:  1988        PMID: 3132874     DOI: 10.1016/s0196-0644(88)80607-3

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  3 in total

1.  The 1998 European Resuscitation Council guidelines for adult advanced life support. Advanced Life Support Working Group of the European Resuscitation Council.

Authors: 
Journal:  BMJ       Date:  1998-06-20

Review 2.  Guidelines for the treatment of acidaemia with THAM.

Authors:  G G Nahas; K M Sutin; C Fermon; S Streat; L Wiklund; S Wahlander; P Yellin; H Brasch; M Kanchuger; L Capan; J Manne; H Helwig; M Gaab; E Pfenninger; T Wetterberg; M Holmdahl; H Turndorf
Journal:  Drugs       Date:  1998-02       Impact factor: 9.546

3.  Acid base changes in arterial and central venous blood during cardiopulmonary resuscitation.

Authors:  D J Steedman; C E Robertson
Journal:  Arch Emerg Med       Date:  1992-06
  3 in total

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