Literature DB >> 31328101

Long-term quality of voice is usually acceptable after initial hoarseness caused by a thyroidectomy or a parathyroidectomy.

Ioannis Christakis1, Patrick Klang1, Nadia Talat1, Gabriele Galata1, Klaus-Martin Schulte1.   

Abstract

BACKGROUND: Vocal cord (VC) palsy following a thyroidectomy or parathyroidectomy can result in significant morbidity for the patient. We aimed to investigate the incidence of VC palsy in a tertiary referral Institution, track the management of these cases and record the long-term outcomes and VC recovery rates.
METHODS: Retrospective review of all thyroidectomy/parathyroidectomy operations performed over 11 years. Patients with an unequivocal hoarse voice postoperatively were included. We analysed the patient's clinical characteristics and voice outcomes, operative, pathology and laryngoscopy reports during their follow-up.
RESULTS: Ten patients fitted the inclusion criteria and were analysed. Median age at date of operation was 47.5 years (range, 16-81 years) and the M:F ratio was 1:2.3 (M:3, F:7). The median FU was 62.5 months (range, 12-144 months). The median hospital stay was 1.5 days (range, 1-87 days). There were 7 recurrent laryngeal nerve (RLN) injuries by manipulation, 1 case of RLN resection, 1 inadvertent division (with primary nerve repair) and 1 RLN was shaved off the thyroid. Long-term voice outcomes for the 7 patients with an RLN manipulation injury were: 3/7 patients had normal voice, 3/7 had moderate hoarseness and 1/7 had long-term hoarseness. The long-term voice outcome of the patient with RLN shaving off the thyroid gland was excellent while the 2 remaining patients (RLN resection and inadvertent division) needed 12 and 18 months respectively to achieve a normal quality of voice. Four out of the 10 patients had permanent VC palsy in the long-term and their voice outcomes varied: 1 patient had a normal voice, 2 patients had moderate hoarseness and 1 patient had persistent hoarseness. Only 1/10 patients did not show any voice improvement after 12 months.
CONCLUSIONS: In the vast majority of cases post-operative hoarseness due to RLN palsy improves in the long-term, albeit voice may not return completely to normal.

Entities:  

Keywords:  Outcomes; palsy; parathyroidectomy; thyroidectomy; vocal cord (VC)

Year:  2019        PMID: 31328101      PMCID: PMC6606476          DOI: 10.21037/gs.2018.09.02

Source DB:  PubMed          Journal:  Gland Surg        ISSN: 2227-684X


  35 in total

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2.  Laryngeal synkinesis revisited.

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3.  Laryngeal reinnervation by ansa cervicalis nerve implantation for unilateral vocal cord paralysis in humans.

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4.  Assessment of the morbidity and complications of total thyroidectomy.

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Journal:  Arch Otolaryngol Head Neck Surg       Date:  2002-04

5.  Voice change following thyroid and parathyroid surgery.

Authors:  Pauline Meek; P N Carding; D H Howard; T W J Lennard
Journal:  J Voice       Date:  2007-06-15       Impact factor: 2.009

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8.  A preliminary study of simple voice assessment in a routine clinical setting to predict vocal cord paralysis after thyroid or parathyroid surgery.

Authors:  B C Hanna; D S Brooker
Journal:  Clin Otolaryngol       Date:  2008-02       Impact factor: 2.597

9.  Nimodipine improves reinnervation and neuromuscular function after injury to the recurrent laryngeal nerve in the rat.

Authors:  Jonas Hydman; Sten Remahl; Gunnar Björck; Mikael Svensson; Per Mattsson
Journal:  Ann Otol Rhinol Laryngol       Date:  2007-08       Impact factor: 1.547

10.  Subjective voice assessment after thyroid surgery: a prospective study of 395 patients.

Authors:  C Page; Rody Zaatar; Aurelie Biet; V Strunski
Journal:  Indian J Med Sci       Date:  2007-08
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Authors:  Tzu-Yen Huang; Wing-Hei Viola Yu; Feng-Yu Chiang; Che-Wei Wu; Shih-Chen Fu; An-Shun Tai; Yi-Chu Lin; Hsin-Yi Tseng; Ka-Wo Lee; Sheng-Hsuan Lin
Journal:  Front Endocrinol (Lausanne)       Date:  2021-11-30       Impact factor: 5.555

4.  The Application Value of the Central Lymph Node Metastasis Risk Assessment Model in Papillary Thyroid Microcarcinoma of Stage cN0: A Study of 828 Patients.

Authors:  Jinqiu Wang; Xianneng Sheng; Yongping Dai; Jiabo Zhang; Lihua Song; Yu Guo
Journal:  Front Endocrinol (Lausanne)       Date:  2022-03-10       Impact factor: 6.055

  4 in total

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