Literature DB >> 31325472

Antiviral agents against African swine fever virus.

Erik Arabyan1, Armen Kotsynyan1, Astghik Hakobyan1, Hovakim Zakaryan2.   

Abstract

African swine fever virus (ASFV) is a significant transboundary virus that continues to spread outside Africa in Europe and most recently to China, Vietnam and Cambodia. Pigs infected with highly virulent ASFV develop a hemorrhagic fever like illness with high lethality reaching up to 100%. There are no vaccines or antiviral drugs available for the prevention or treatment of ASFV infections. We here review molecules that have been reported to inhibit ASFV replication, either as direct-acting antivirals or host-targeting drugs as well as those that act via a yet unknown mechanism. Prospects for future antiviral research against ASFV are also discussed.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  African swine fever virus; Antiviral; Flavonoid; Nucleoside; Pig

Year:  2019        PMID： 31325472     DOI： 10.1016/j.virusres.2019.197669

Source DB:  PubMed          Journal:  Virus Res        ISSN： 0168-1702            Impact factor:   3.303


  8 in total

Review 1.  Cell Lines for the Development of African Swine Fever Virus Vaccine Candidates: An Update.

Authors:  Dionigia Meloni; Giulia Franzoni; Annalisa Oggiano
Journal:  Vaccines (Basel)       Date:  2022-04-29

2.  Complete genome analysis of African swine fever virus responsible for outbreaks in domestic pigs in 2018 in Burundi and 2019 in Malawi.

Authors:  Jean N Hakizimana; Jean B Ntirandekura; Clara Yona; Lionel Nyabongo; Gladson Kamwendo; Julius L C Chulu; Désiré Ntakirutimana; Olivier Kamana; Hans Nauwynck; Gerald Misinzo
Journal:  Trop Anim Health Prod       Date:  2021-08-17       Impact factor: 1.559

3.  HRP-conjugated-nanobody-based cELISA for rapid and sensitive clinical detection of ASFV antibodies.

Authors:  Huijun Zhao; Jiahui Ren; Shuya Wu; Haoran Guo; Yongkun Du; Bo Wan; Pengchao Ji; Yanan Wu; Guoqing Zhuang; Angke Zhang; Gaiping Zhang
Journal:  Appl Microbiol Biotechnol       Date:  2022-05-25       Impact factor: 5.560

4.  Comprehensive Analysis of G-Quadruplexes in African Swine Fever Virus Genome Reveals Potential Antiviral Targets by G-Quadruplex Stabilizers.

Authors:  Elishiba Muturi; Fei Meng; Huan Liu; Mengwei Jiang; Hongping Wei; Hang Yang
Journal:  Front Microbiol       Date:  2021-12-16       Impact factor: 5.640

5.  Levistolide A Inhibits PEDV Replication via Inducing ROS Generation.

Authors:  Wei Zeng; Jingping Ren; Zhonghua Li; Changsheng Jiang; Qi Sun; Chang Li; Wan Li; Wentao Li; Qigai He
Journal:  Viruses       Date:  2022-01-27       Impact factor: 5.048

6.  Structural Insight into Molecular Inhibitory Mechanism of InsP6 on African Swine Fever Virus mRNA-Decapping Enzyme g5Rp.

Authors:  Yan Yang; Changhui Zhang; Xuehui Li; Li Li; Yanjuan Chen; Xin Yang; Yao Zhao; Cheng Chen; Wei Wang; Zhihui Zhong; Cheng Yang; Zhen Huang; Dan Su
Journal:  J Virol       Date:  2022-04-28       Impact factor: 6.549

7.  Inhibition of BET Family Proteins Suppresses African Swine Fever Virus Infection.

Authors:  Yaru Zhao; Qingli Niu; Saixia Yang; Jifei Yang; Zhonghui Zhang; Shuxian Geng; Jie Fan; Zhijie Liu; Guiquan Guan; Zhiqing Liu; Jia Zhou; Haitao Hu; Jianxun Luo; Hong Yin
Journal:  Microbiol Spectr       Date:  2022-06-27

8.  Toosendanin suppresses African swine fever virus replication through upregulating interferon regulatory factor 1 in porcine alveolar macrophage cultures.

Authors:  Yuanjia Liu; Xinheng Zhang; Zexin Liu; Li Huang; Weixin Jia; Xinlei Lian; Changjiang Weng; Guihong Zhang; Wenbao Qi; Jianxin Chen
Journal:  Front Microbiol       Date:  2022-08-30       Impact factor: 6.064
  8 in total

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