Tavish Arora 1 , P G Mantur 2 , R C Bidri 3 , M S Mulimani 4 Show Affiliations »
Abstract
BACKGROUND: Stroke is a growing disease and it is the second common cause of death in the world after coronary heart disease especially in the elderly. In patients with acute stroke hyperuricemia was significantly higher than normal population with associated dyslipidemia. Hyperuricemia has been associated with decreased amount of HDL cholesterol and increased amounts of triglycerides and LDL cholesterol. AIM: :Serum uric acid levels and serum lipid levels in patients with ischemic cerebrovascular accident. MATERIAL AND METHODS: This was a cross-sectional study carried out between January 2015 - June 2016, which included 60 cases of acute ischemic stroke. Serum uric acid levels and serum lipid levels was done in all the patients and was statistically analyzed. RESULTS: A total of 60 patients with ischemic stroke were included in the study. Out of which 43 (71.7%) were males and 17 (28.3%) were females. The mean age of the patients was 63.2 ±14.8. Mean serum uric acid levels in the patients studied was 5.5 ± 1.7, and 18 patients (30%) were hyperuricemic. Serum uric acid levels were significantly higher in females (6.2 ± 1.9) compared to the males (5.2 ±1.6). It was predominant in the age group between 56-70 years. Dyslipidemia was seen in 49 (81.7%) patients (Males were 36 and females were 13).. More than one lipid parameter was seen to be deranged in 10 male patients and 4 female patients. Of them 87.75% of patients had low HDL levels, 36.73%, 10.20% and 8.16% patient had high cholesterol, triglycerides and LDL levels respectively. The study also showed that 15 patients had both hyperuricemia and dyslipidemia. CONCLUSION: Hyperuricemia and its accompanying dyslipidemia can be considered as the risk factor for acute ischemic stroke. © Journal of the Association of Physicians of India 2011.
BACKGROUND: Stroke is a growing disease and it is the second common cause of death in the world after coronary heart disease especially in the elderly. In patients with acute stroke hyperuricemia was significantly higher than normal population with associated dyslipidemia. Hyperuricemia has been associated with decreased amount of HDL cholesterol and increased amounts of triglycerides and LDL cholesterol. AIM: :Serum uric acid levels and serum lipid levels in patients with ischemic cerebrovascular accident. MATERIAL AND METHODS: This was a cross-sectional study carried out between January 2015 - June 2016, which included 60 cases of acute ischemic stroke. Serum uric acid levels and serum lipid levels was done in all the patients and was statistically analyzed. RESULTS: A total of 60 patients with ischemic stroke were included in the study. Out of which 43 (71.7%) were males and 17 (28.3%) were females. The mean age of the patients was 63.2 ±14.8. Mean serum uric acid levels in the patients studied was 5.5 ± 1.7, and 18 patients (30%) were hyperuricemic. Serum uric acid levels were significantly higher in females (6.2 ± 1.9) compared to the males (5.2 ±1.6). It was predominant in the age group between 56-70 years. Dyslipidemia was seen in 49 (81.7%) patients (Males were 36 and females were 13).. More than one lipid parameter was seen to be deranged in 10 male patients and 4 female patients. Of them 87.75% of patients had low HDL levels, 36.73%, 10.20% and 8.16% patient had high cholesterol, triglycerides and LDL levels respectively. The study also showed that 15 patients had both hyperuricemia and dyslipidemia. CONCLUSION: Hyperuricemia and its accompanying dyslipidemia can be considered as the risk factor for acute ischemic stroke. © Journal of the Association of Physicians of India 2011.
Entities: Chemical
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Year: 2018
PMID： 31325266
Source DB: PubMed Journal: J Assoc Physicians India ISSN： 0004-5772