Literature DB >> 3132416

Factor I (C3b inactivator) polymorphism among five populations in Eurasia.

I Yuasa1, K Umetsu, K Suenaga, K Ito, M Iha, H Hirata, M Robinet-Lévy, T Inoue, K Okada.   

Abstract

Factor I (C3b inactivator) polymorphism in the Japanese (in Western and Southern Japan), Taiwanese, Nepalese and French was studied using isoelectric focusing on polyacrylamide gels. The exposure of passively blotted nitrocellulose membranes to glutaraldehyde vapor facilitated the subsequent immunodetection of a low concentration of factor I and permitted the reliable identification of the three phenotypes determined by two codominant alleles FI*A and FI*B. The data indicated a west-to-east genocline, ranging from France to Western Japan, in which FI*A changed from 0.006 to 0.120.

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Year:  1988        PMID: 3132416     DOI: 10.1159/000153764

Source DB:  PubMed          Journal:  Hum Hered        ISSN: 0001-5652            Impact factor:   0.444


  2 in total

1.  A new polymorphic variant of human complement factor I.

Authors:  M Zhou; B Larsen
Journal:  Hum Genet       Date:  1989-07       Impact factor: 4.132

2.  Molecular basis of complement factor I (CFI) polymorphism: one of two polymorphic suballeles responsible for CFI A is Japanese-specific.

Authors:  Isao Yuasa; Mayumi Nakagawa; Kazuo Umetsu; Shinji Harihara; Aya Matsusue; Hiroaki Nishimukai; Yasuo Fukumori; Naruya Saitou; Kyung Sook Park; Feng Jin; Gérard Lucotte; Prasanta K Chattopadhyay; Lotte Henke; Jürgen Henke
Journal:  J Hum Genet       Date:  2008-09-30       Impact factor: 3.172

  2 in total

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