Su-Min Jeong1, Dong Wook Shin2, Kyungdo Han3, Jin Hyung Jung3, Sohyun Chun4, Hee-Won Jung5, Ki Young Son6. 1. Department of Family Medicine & Supportive Care Center, Samsung Medical Center, Sungkyunkwan School of Medicine, Seoul, Republic of Korea; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. 2. Department of Family Medicine & Supportive Care Center, Samsung Medical Center, Sungkyunkwan School of Medicine, Seoul, Republic of Korea. Electronic address: dwshin.md@gmail.com. 3. Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. 4. International Healthcare Center, Samsung Medical Center, Seoul, Republic of Korea. 5. Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea. 6. Department of Family Medicine, Asan Medical Center, Seoul, Republic of Korea.
Abstract
PURPOSE: The timed up-and-go (TUG) test is a validated screening tool to assess fall risk. This study evaluated the association between the TUG test and future fractures, which are a tangible clinical complication of falling. METHODS: We included 1,070,320 participants who participated in the National Screening Program for Transitional Ages for Koreans aged 66 years old from 2009 to 2014. Among them, 355,753 women underwent dual-energy X-ray absorptiometry. TUG times were classified as <10 s or ≥10 s. The incidence of fractures, including vertebral, hip, and other sites, was determined using claims data from the National Health Information database. RESULTS: During the mean follow-up period of 4.4 ± 1.8 years, participants with slow TUG times had a significantly increased risk of fractures compared with those who had normal TUG times: any fractures (adjusted hazard ratio [aHR] = 1.08, 95% confidence interval [CI] = 1.06-1.10), vertebral fracture (aHR = 1.14, 95% CI = 1.11-1.16), hip fracture (aHR = 1.21, 95% CI = 1.13-1.29), and other fractures (upper arm, forearm, and lower leg; aHR = 1.02, 95% CI = 1.00-1.05). Among women with bone mineral density (BMD) results, slow TUG performance was associated with an increased risk of fracture independent of BMD. CONCLUSIONS: The TUG test, as an indicator of physical performance, can provide information about future fracture risk above that provided by BMD. Conducting the TUG test to assess fracture risk should be considered to improve fracture risk assessment and propose interventions to improve physical performance, thereby reducing fracture risk.
PURPOSE: The timed up-and-go (TUG) test is a validated screening tool to assess fall risk. This study evaluated the association between the TUG test and future fractures, which are a tangible clinical complication of falling. METHODS: We included 1,070,320 participants who participated in the National Screening Program for Transitional Ages for Koreans aged 66 years old from 2009 to 2014. Among them, 355,753 women underwent dual-energy X-ray absorptiometry. TUG times were classified as <10 s or ≥10 s. The incidence of fractures, including vertebral, hip, and other sites, was determined using claims data from the National Health Information database. RESULTS: During the mean follow-up period of 4.4 ± 1.8 years, participants with slow TUG times had a significantly increased risk of fractures compared with those who had normal TUG times: any fractures (adjusted hazard ratio [aHR] = 1.08, 95% confidence interval [CI] = 1.06-1.10), vertebral fracture (aHR = 1.14, 95% CI = 1.11-1.16), hip fracture (aHR = 1.21, 95% CI = 1.13-1.29), and other fractures (upper arm, forearm, and lower leg; aHR = 1.02, 95% CI = 1.00-1.05). Among women with bone mineral density (BMD) results, slow TUG performance was associated with an increased risk of fracture independent of BMD. CONCLUSIONS: The TUG test, as an indicator of physical performance, can provide information about future fracture risk above that provided by BMD. Conducting the TUG test to assess fracture risk should be considered to improve fracture risk assessment and propose interventions to improve physical performance, thereby reducing fracture risk.
Authors: Ji Eun Lee; Hyejin Chun; Young Sang Kim; Hee Won Jung; Il Young Jang; Hyun Min Cha; Ki Young Son; Belong Cho; In Soon Kwon; Jong Lull Yoon Journal: J Korean Med Sci Date: 2020-01-20 Impact factor: 2.153
Authors: B A M Larsson; L Johansson; H Johansson; K F Axelsson; N Harvey; L Vandenput; P Magnusson; E McCloskey; E Liu; J A Kanis; D Sundh; M Lorentzon Journal: Osteoporos Int Date: 2020-10-21 Impact factor: 4.507