K M Islam1, Poppy E Deviany2, Trisari Anggondowati2, June E Ryan3, Ann Fetrick2, Danstan Bagenda4, Mehmet S Copur5, Addison Tolentino6,7, Irfan Vaziri8, Heidi A McKean6, Steven Dunder9, Jhanelle E Gray10, Chao M D Huang11, Apar Kishor Ganti4,12. 1. Augusta University Georgia Medical College, Augusta, GA. 2. University of Nebraska Medical Center College of Public Health, Omaha, NE. 3. Nebraska Cancer Coalition, Omaha, NE. 4. University of Nebraska Medical Center College of Medicine, Omaha, NE. 5. St Francis Cancer Treatment Center, Grand Island, NE. 6. Avera Cancer Institute, Sioux Falls, SD. 7. St Luke's Hospital of Kansas City, Kansas City, MO. 8. Great Plains Health, North Platte, NE. 9. Southeast Nebraska Cancer Center, Lincoln, NE. 10. H. Lee Moffitt Cancer Center, Tampa, FL. 11. Kansas City VA Medical Center-Kansas City Veterans Administration Health Care System, Kansas City, MO. 12. Omaha VA Medical Center-Nebraska-Western Iowa Veterans Administration Health Care System, Omaha, NE.
Abstract
PURPOSE: In the United States, lung cancer accounts for 14% of cancer diagnoses and 28% of cancer deaths annually. Because no cure exists for advanced lung cancer, the primary treatment goal is to prolong survival. OBJECTIVES: The study aim was to determine whether individual preferences, characteristics, and treatment experiences affect the meaning of treatment success. MATERIALS AND METHODS: A quantitative study using an observational, longitudinal cohort of patients with advanced stage non-small-cell lung cancer was conducted. Data sources included medical records and patient interviews. Data were analyzed using χ2, Fisher's exact, and McNemar's tests, as well as logistic regressions. RESULTS: At the first interview of 235 individuals, 12% considered survival alone as their definition of treatment success; others defined treatment success as survival plus other aspects, such as quality of life and reaching an important personal goal. As they moved through chemotherapy, 47% of the patients changed their definition of treatment success. Bivariate analysis showed that patients with lower incomes tended to be more likely to change their definition of treatment success compared with their counterparts with higher income (P = .0245). CONCLUSION: By taking chemotherapy, patients expect to increase their odds of survival and want to maintain the quality of life and functionality. A patient's definition of treatment success is often changing as treatment continues, making it appropriate to ensure patient-provider communication throughout their clinical care. The study results are limited to patients with advanced non-small-cell lung cancer and drawn from a predominantly white patient population, mainly from the US Midwest.
PURPOSE: In the United States, lung cancer accounts for 14% of cancer diagnoses and 28% of cancer deaths annually. Because no cure exists for advanced lung cancer, the primary treatment goal is to prolong survival. OBJECTIVES: The study aim was to determine whether individual preferences, characteristics, and treatment experiences affect the meaning of treatment success. MATERIALS AND METHODS: A quantitative study using an observational, longitudinal cohort of patients with advanced stage non-small-cell lung cancer was conducted. Data sources included medical records and patient interviews. Data were analyzed using χ2, Fisher's exact, and McNemar's tests, as well as logistic regressions. RESULTS: At the first interview of 235 individuals, 12% considered survival alone as their definition of treatment success; others defined treatment success as survival plus other aspects, such as quality of life and reaching an important personal goal. As they moved through chemotherapy, 47% of the patients changed their definition of treatment success. Bivariate analysis showed that patients with lower incomes tended to be more likely to change their definition of treatment success compared with their counterparts with higher income (P = .0245). CONCLUSION: By taking chemotherapy, patients expect to increase their odds of survival and want to maintain the quality of life and functionality. A patient's definition of treatment success is often changing as treatment continues, making it appropriate to ensure patient-provider communication throughout their clinical care. The study results are limited to patients with advanced non-small-cell lung cancer and drawn from a predominantly white patient population, mainly from the US Midwest.
Authors: Mitchell S von Itzstein; Elda Railey; Mary L Smith; Carol B White; George W Sledge; John R Howell; Wendy Lawton; Donna M Marinucci; Nisha Unni; David E Gerber Journal: Cancer Date: 2020-01-22 Impact factor: 6.860
Authors: Morhaf Al Achkar; Upal Basu Roy; Eugene Manley; Maisha Standifer; Christina Baik; Casey A Walsh Journal: Support Care Cancer Date: 2022-08-11 Impact factor: 3.359
Authors: Angela M Stover; Rachel Kurtzman; Jennifer Walker Bissram; Jennifer Jansen; Philip Carr; Thomas Atkinson; C Tyler Ellis; Ashley T Freeman; Kea Turner; Ethan M Basch Journal: Cancers (Basel) Date: 2021-07-20 Impact factor: 6.575