Literature DB >> 31319725

Elevation of Serum CEA in Patients with Squamous Cell Carcinoma of the Anus.

Gabriel T Raab1, Daniel S O'Neil2, Ravi P Kiran1,3,4, Daniel L Feingold3,4, Steven A Lee-Kong3,4, David P Horowitz3,5, Alfred I Neugut1,2,3.   

Abstract

The proportion of anal cancer cases that produce elevated carcinoembryonic antigen (CEA) levels is not well described in the medical literature. In this study, we used electronic health record data from a single urban cancer center to identify patients from 2004-2018 with anal cancer who have also had a pre-initial treatment CEA measurement. We identified 40 patients who met our eligibility criteria. Of those, 11 (27.5%) had an elevated pretreatment CEA. Elevated CEA was not associated with any of the clinical or demographic covariates; however, three out of five patients with a recurrence had an elevated CEA.

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Keywords:  CEA; Cancer biomarkers; carcinoembryonic antigen; recurrence; squamous cell carcinoma of the anus

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Year:  2019        PMID: 31319725     DOI: 10.1080/07357907.2019.1636388

Source DB:  PubMed          Journal:  Cancer Invest        ISSN: 0735-7907            Impact factor:   2.176


  1 in total

1.  Expression Levels and Clinical Significance of Serum miR-497, CEA, CA24-2, and HBsAg in Patients with Colorectal Cancer.

Authors:  Yan Liu; Jie Chen
Journal:  Biomed Res Int       Date:  2022-08-11       Impact factor: 3.246

  1 in total

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