OBJECTIVE: To determine the clinical implications of scalp ictal EEG pattern in patients with temporal lobe epilepsy (TLE). METHODS: Scalp EEG ictal patterns were retrospectively determined in 27 consecutive patients with medically refractory temporal lobe epilepsy who underwent phase-1 scalp video-EEG and phase-2 simultaneous scalp and intracranial video-EEG recordings for pre-surgical evaluation. RESULTS: Of the 192 temporal lobe seizures recorded during phase-1 and phase-2 scalp video-EEG studies, 124 (65%) seizures were associated with theta/alpha (5-9 Hz) ictal onset pattern, and 68 (35%) seizures were associated with delta (2-5 Hz) ictal onset pattern. Fourteen (52%) patients had exclusively theta/alpha ictal onset, 3 (11%) patients had exclusively delta ictal onset, and 10 (37%) patients had mixed theta/alpha and delta ictal onsets. MTLE was observed in 26 patients who had 124 seizures with theta/alpha ictal onset and 59 seizures with delta ictal onset. LTLE was observed in one patient who had 9 seizures with delta ictal onset. Scalp ictal EEG pattern was not significantly correlated with postsurgical seizure outcomes. CONCLUSIONS: Both scalp delta and theta/alpha ictal onset patterns can be commonly found in patients with MTLE. SIGNIFICANCE: Scalp delta ictal onset is not a unique EEG pattern for LTLE as commonly believed.
OBJECTIVE: To determine the clinical implications of scalp ictal EEG pattern in patients with temporal lobe epilepsy (TLE). METHODS: Scalp EEG ictal patterns were retrospectively determined in 27 consecutive patients with medically refractory temporal lobe epilepsy who underwent phase-1 scalp video-EEG and phase-2 simultaneous scalp and intracranial video-EEG recordings for pre-surgical evaluation. RESULTS: Of the 192 temporal lobe seizures recorded during phase-1 and phase-2 scalp video-EEG studies, 124 (65%) seizures were associated with theta/alpha (5-9 Hz) ictal onset pattern, and 68 (35%) seizures were associated with delta (2-5 Hz) ictal onset pattern. Fourteen (52%) patients had exclusively theta/alpha ictal onset, 3 (11%) patients had exclusively delta ictal onset, and 10 (37%) patients had mixed theta/alpha and delta ictal onsets. MTLE was observed in 26 patients who had 124 seizures with theta/alpha ictal onset and 59 seizures with delta ictal onset. LTLE was observed in one patient who had 9 seizures with delta ictal onset. Scalp ictal EEG pattern was not significantly correlated with postsurgical seizure outcomes. CONCLUSIONS: Both scalp delta and theta/alpha ictal onset patterns can be commonly found in patients with MTLE. SIGNIFICANCE: Scalp delta ictal onset is not a unique EEG pattern for LTLE as commonly believed.
Authors: Zachary Fitzgerald; Marcia Morita-Sherman; Olivia Hogue; Boney Joseph; Marina K M Alvim; Clarissa L Yasuda; Deborah Vegh; Dileep Nair; Richard Burgess; William Bingaman; Imad Najm; Michael W Kattan; Ingmar Blumcke; Gregory Worrell; Benjamin H Brinkmann; Fernando Cendes; Lara Jehi Journal: Epilepsia Date: 2021-08-02 Impact factor: 6.740