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Literature DB >> 3131880

Drosophila melanogaster as an experimental organism.

Abstract

The fruit fly Drosophila melanogaster has been used as an experimental organism in studies of genetics since the early 1900s. It is now widely used not only in classical and molecular genetics but also, with many new biochemical, cell biological, and physiological techniques, to research problems requiring a multidisciplinary approach, such as those of developmental biology and neurobiology.

Entities: Species

Mesh：

Year: 1988 PMID： 3131880 DOI： 10.1126/science.3131880

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

37 in total

1. A genetic screen for novel components of the Ras/Mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein.

Authors: I Rebay; F Chen; F Hsiao; P A Kolodziej; B H Kuang; T Laverty; C Suh; M Voas; A Williams; G M Rubin
Journal: Genetics Date: 2000-02 Impact factor: 4.562

Drosophila melanogaster as an experimental organism.

1. A genetic screen for novel components of the Ras/Mitogen-activated protein kinase signaling pathway that interact with the yan gene of Drosophila identifies split ends, a new RNA recognition motif-containing protein.

2. Circadian oscillations in period gene mRNA levels are transcriptionally regulated.

3. Two forms of Drosophila melanogaster Gs alpha are produced by alternate splicing involving an unusual splice site.

4. Coordination of legs during straight walking and turning in Drosophila melanogaster.

5. The Drosophila couch potato gene: an essential gene required for normal adult behavior.

6. Fly neurons in culture: a model for neural development and pathology.

7. The glucose transporter (GLUT4) enhancer factor is required for normal wing positioning in Drosophila.

8. "Site-selected" transposon mutagenesis of Drosophila.

9. Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype.

10. Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast.