Klaudia Duka Glavor1,2, Marina Titlić3,4, Gorka Vuletić5,6, Anamarija Mrđen7,8, Marina Maras Šimunić4,9. 1. Department of Neurology, General Hospital Zadar, Bože Peričića 5, Zadar, Croatia. klaudia.dukaglavor@gmail.com. 2. Department of Health Studies, University of Zadar, Zadar, Croatia. klaudia.dukaglavor@gmail.com. 3. Department of Neurology, University Hospital Centre Split, Split, Croatia. 4. School of Medicine, University of Split, Split, Croatia. 5. Department of Psychology, Faculty of Humanities and Social Science in Osijek, J. J. Strossmayer University of Osijek, Osijek, Croatia. 6. A. Stampar School of Public Health, School of Medicine University of Zagreb, Zagreb, Croatia. 7. Department of Neurology, General Hospital Zadar, Bože Peričića 5, Zadar, Croatia. 8. Department of Health Studies, University of Zadar, Zadar, Croatia. 9. Department of Radiology, University Hospital Centre Split, Split, Croatia.
Abstract
OBJECTIVE: The aim of this study was to compare self-perceived health between migraine and early stages of relapsing-remitting multiple sclerosis (RRMS) and to explore whether and how accurate those health domains predict overall quality of life. METHODS: Ninety patients aged 18-55 years were enrolled in this cross-sectional study. Thirty follow-up outpatients were recruited with migraine (with or without aura), 30 patients with RRMS, and 30 healthy subjects. They were asked to complete the Health status questionnaire (SF-36) and Personal Wellbeing Index (PWI). RESULTS: Patients with RRMS and migraine had significantly worse self-reported health regarding role limitation due to physical problems and general health than the healthy control group. Additionally, migraine patients had more bodily pain, while RRMS patients expressed more difficulties regarding physical functioning. Differences between migraine and RRMS patients were not significant. Hierarchical regression analysis revealed that role limitation due to physical problems, mental health, and general health represents significant predictors of overall quality of life. CONCLUSIONS: Migraine may affect quality of life similarly to early stages of RRMS. Bio-psycho-socio-medical understanding of the two diseases and their impact on patients QoL should be reconsidered.
OBJECTIVE: The aim of this study was to compare self-perceived health between migraine and early stages of relapsing-remitting multiple sclerosis (RRMS) and to explore whether and how accurate those health domains predict overall quality of life. METHODS: Ninety patients aged 18-55 years were enrolled in this cross-sectional study. Thirty follow-up outpatients were recruited with migraine (with or without aura), 30 patients with RRMS, and 30 healthy subjects. They were asked to complete the Health status questionnaire (SF-36) and Personal Wellbeing Index (PWI). RESULTS:Patients with RRMS and migraine had significantly worse self-reported health regarding role limitation due to physical problems and general health than the healthy control group. Additionally, migrainepatients had more bodily pain, while RRMS patients expressed more difficulties regarding physical functioning. Differences between migraine and RRMS patients were not significant. Hierarchical regression analysis revealed that role limitation due to physical problems, mental health, and general health represents significant predictors of overall quality of life. CONCLUSIONS:Migraine may affect quality of life similarly to early stages of RRMS. Bio-psycho-socio-medical understanding of the two diseases and their impact on patients QoL should be reconsidered.
Entities:
Keywords:
Migraine; Quality of life; Relapsing-remitting multiple sclerosis
Authors: Katherine S Button; John P A Ioannidis; Claire Mokrysz; Brian A Nosek; Jonathan Flint; Emma S J Robinson; Marcus R Munafò Journal: Nat Rev Neurosci Date: 2013-04-10 Impact factor: 34.870
Authors: Chris H Polman; Stephen C Reingold; Brenda Banwell; Michel Clanet; Jeffrey A Cohen; Massimo Filippi; Kazuo Fujihara; Eva Havrdova; Michael Hutchinson; Ludwig Kappos; Fred D Lublin; Xavier Montalban; Paul O'Connor; Magnhild Sandberg-Wollheim; Alan J Thompson; Emmanuelle Waubant; Brian Weinshenker; Jerry S Wolinsky Journal: Ann Neurol Date: 2011-02 Impact factor: 10.422