Acceptability and implementation challenges of smartphone-based training of community health nurses for visual inspection with acetic acid in Ghana: mHealth and cervical cancer screening.

OBJECTIVE: To explore acceptability and feasibility of smartphone-based training of low-level to mid-level health professionals in cervical cancer screening using visual inspection with acetic acid (VIA)/cervicography.
DESIGN: In 2015, we applied a qualitative descriptive approach and conducted semi-structured interviews and focus groups to assess the perceptions and experiences of community health nurses (CHNs) (n=15) who performed smartphone-based VIA, patients undergoing VIA/cryotherapy (n=21) and nurse supervisor and the expert reviewer (n=2).
SETTING: Community health centres (CHCs) in Accra, Ghana.
RESULTS: The 3-month smartphone-based training and mentorship was perceived as an important and essential complementary process to further develop diagnostic and management competencies. Cervical imaging provided peer-to-peer learning opportunities, and helped better communicate the procedure to and gain trust of patients, provide targeted education, improve adherence and implement quality control. None of the patients had prior screening; they overwhelmingly accepted smartphone-based VIA, expressing no significant privacy issues. Neither group cited significant barriers to performing or receiving VIA at CHCs, the incorporation of smartphone imaging and mentorship via text messaging. CHNs were able to leverage their existing community relationships to address a lack of knowledge and misperceptions. Patients largely expressed decision-making autonomy regarding screening. Negative views and stigma were present but not significantly limiting, and the majority felt that screening strategies were acceptable and effective.
CONCLUSIONS: Our findings suggest the overall acceptability of this approach from the perspectives of all stakeholders with important promises for smartphone-based VIA implementation. Larger-scale health services research could further provide important lessons for addressing this burden in low-income and middle-income countries. © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Using a qualitative descriptive approach, this is the first paper that describes perceptions and experiences of nurses and patients in regards to smartphone-based visual inspection with acetic acid (VIA) for cervical cancer screening.

Our findings provide important insight into the overall acceptability and feasibility of this approach from the perspectives of all stakeholders.

The smartphone-based training of VIA has important promises for VIA implementation and sustainability of national programmes.

This qualitative study by its nature only generates hypotheses, which need to be further tested quantitatively for validity and generalisability.

Larger-scale health services research would further provide important lessons for addressing this burden in low-income and middle-income countries.

Introduction

Worldwide, cervical cancer kills around a quarter of a million women annually, with the majority in low-income and middle-income countries (LMICs).1–3 In sub-Saharan Africa (SSA), lack of access to proper screening and treatment of precancerous lesions contributes to high cervical cancer mortality.4–8 Visual inspection of the cervix under acetic acid (VIA) is an effective screening method for cervical cancer,9–20 but is not readily accessible in most SSA countries.10 19 20 Periodic cervical cancer screening using VIA conducted every 24 months by trained primary health workers has resulted in a 31% reduction in cervical cancer mortality over 12 years.21 Ghana’s National Screening Programme recommends VIA screening plus cryotherapy for women aged 25–4522 23; however, it has not been widely available due to an inability to integrate VIA into the primary healthcare system.5 20 23 In Ghana, the Community-based Health Planning and Services (CHPS) programme has significantly improved access to primary care through community health nurses (CHNs), who provide services at the district level in community health centres (CHCs).24 25

A shortage of healthcare providers and comprehensive training of low-level to mid-level healthcare workers in VIA contribute to the lack of VIA accessibility in SSA.6 7 19 26–29 Additionally, maintaining competencies and accuracy of VIA are major challenges as the standard short-term onsite VIA trainings may not guarantee skills retention.19 28 29 The addition of cervicography to VIA has improved accuracy and diagnostic abilities,30–35 but its logistical barriers and cost have impeded large-scale availability for practitioners. The use of smartphones with digital cameras has presented the opportunity to use smartphones for cervicography to enhance training of low- to mid-level health professionals, facilitate storage of patient’s screening records, transfer images for expert opinion and re-train via text messaging.36–38 However, acceptability and feasibility of smartphone-based VIA have not been systematically evaluated and have implications for large-scale implementation. In a related 2016 pilot study, the authors have demonstrated the impact of smartphone-based imaging and mentorship on improving and maintaining VIA diagnostic skills among CHWs.36 In this study, we aimed to evaluate the perceptions and experiences of both CHNs who performed smartphone-based VIA/cervicography and women undergoing VIA/cryotherapy in CHCs in Accra, Ghana.

Methods

Setting and study participants

The catchment area for this study included 15 CHPS demarcated zones in the Ga East Municipal of Greater Accra Region, Ghana, with a total of 30 CHNs. In 2015, 15 CHNs were recruited from two subdistricts (Dome and Taifa) in collaboration with officials from the CHPS programme. These CHNs, who had prior working knowledge of community and health resources, participated in a 2-week onsite introductory VIA/cervicography training modelled after the JHIPEGO course used globally,39 plus 3 months smartphone-based mentorship for improving VIA diagnostic and management skills using imaging of the cervix.36 We interviewed all CHNs (n=15) who participated in this study. They had 2 years of nurse training and were employed by the Ghana Health Service that participated in this study. Additionally, we used prospective purposive and criteria sampling techniques to recruit patient participants (n=21, of 169 screened) including those of different ages, those receiving cryotherapy or further treatment (n=6), and from both CHCs. To triangulate data, an expert reviewer and a head nurse were additionally interviewed.

Multiple smartphones were evaluated in a pilot assessment for their quality of imaging, cost and ease of use. The Samsung Duos was the best option available in Ghana at the time of this study with reasonable image resolution, ability to auto and manually focus, LED camera flash and battery life. A protocolised consistent approach to photography and image transfer was established and used throughout. Training in effective photography of the cervix using smartphones and proper lighting and position of patient as well as the camera was provided during the in-person training. During the immediate feedback phase, for each patient, the CHN sent the best image captured to the mentor for feedback; this resulted in an average of 11 images per CHN.

Data collection and procedures

Data collection included semi-structured individual interviews conducted at the CHCs in either English or a local Ghanaian language with a trained professional interpreter. Nine CHNs participated in an additional focus group. CHNs responded to 10 open-ended questions with probes regarding attitudes, perceptions of and experience with onsite training, cervical cancer screening, smartphone imaging of the cervix, a 3-month mentorship via text messaging, opinions on the feasibility of VIA/cervicography screening at CHCs and at the national level, and overall logistical barriers and further recommendations (for interview tool, please see online supplementary file 1). Topics for the expert reviewer and head nurse included logistical barriers, opportunities and experiences with VIA/cervicography training and mentorship. Patients were posed 10 open-ended questions with directing probes regarding knowledge, attitudes and experience with cervical cancer screening, VIA/cervicography or cryotherapy and imaging of the cervix using smartphones, privacy concerns, stigma and perceptions of community members, and suggestions to improve the screening programme (for interview tool, please see online supplementary file 2). Interviewers (RA and AN) had previously worked with CHNs in the CHPS programme, and had prior knowledge of the programme, working conditions and health system characteristics in the CHCs. At the beginning of each interview, it was made clear that the information from the participants would be deidentified with no direct link between interview data and participants’ identifying information so that they could discuss their experience openly. All interviews were audiorecorded. Notes were taken by trained interpreters, translated into English when needed and checked for interpreter accuracy. Informed consent was obtained from all participants. We clarified that participation would not affect participants in any negative way and that they could withdraw answers or from the study at any time and that non-participation would not adversely affect participants.

Data analysis

Data were analysed by two researchers (RA and HC) using a qualitative descriptive approach and content analysis to identify core perceptions, experience and attitudes. We developed preliminary coding, performed critical deliberation about initial codes and reviewed codes for similarities and variations to assure a high level of agreement. Codes fell into distinct but overarching categories. Reviewers independently reviewed and coded all transcripts, then met to review codes, discuss and identify concepts grouped into the specific categories and described and agreed on major important emergent themes. The study was approved by the Noguchi Institute Institutional Review Board in Ghana as well as the IRB of New York University School of Medicine.

Patient and public involvement

At early stage of this study, formal and informal discussions with patients and non-study staff of CHCs were held to better develop the research question and understand the potential impact of research, and factor in their current experience and priorities to the extent they were relevant and possible.

Results

Average age for nurses was 28.2 years (SD, 2.9); 100% female. Average age for the patients was 33.8 years (SD, 7); 69% were married or had partners; average age at first sexual intercourse was 20.1 years (SD, 4.1); average lifetime sexual partners was 3.1 (SD, 2) and average number of living children 2.1 (SD, 1.6). Analysis of interviews and focus groups with screening providers, patients and health staff revealed distinct but overarching themes.

Perception and experiences of community health nurses

Quotes supporting findings on the perceptions and experiences of CHNs can be found in table 1. CHNs viewed the onsite training and its format as effective and comfortable. The majority reported that working with a combination of the speculum, mannequins, real patients and flashcards helped prepare them for actual screenings. Although all agreed that learning the pelvic anatomy was interesting, some mentioned that classroom lectures were not contextual, and that they learnt more working with real patients. Majority stated that it was beneficial that the trainer taught them how to use the speculum, take photos and do the gynaecology exam. Largely, nurses did not feel that financial incentives were needed to encourage learning.

Table 1

Experiences and perceptions of CHNs, smartphone-based VIA cervical cancer screening, Accra, Ghana, 2015

Theme	Quote
Perceptions and experiences regarding onsite training and smartphone-based mentorship
In-person training perceptions	“During the training because of the way our teacher taught us, the whole thing, I became very much confident that when it comes to screening a client it wouldn’t be difficult for me because from the beginning we learnt about the theory and as the time went on we learnt about the practical. At least I had the chance during a day to screen about three to four clients by the end of the program (so) I was very much confident to screen clients for cervical cancer” [CHN3].
	“…the theory was a bit in a haste, I didn’t understand what (the lecturer) was saying and that was my first time of hearing those big big words but when I got to the practical stage I understood” [CHN6]
Importance of 3-month support period	“That one it has been very much helpful to us because there’re some cases that you will see them to be positive or sometimes you will see them to be negative but when you communicate with them (mentors) you will see that sometimes the feedback or the answer they give you is quite different from what you see… after we communicate with them (mentors) sometimes they freshen our memories on what we learnt so far so that you will be able to know (why) that that this is also a positive or a negative so communicating with them has been very good.” [CHN7]
Importance of exposure to positive cases in learning	“…when we went for the training and we came back, it wasn’t easy to locate the SC junction and those things so for the first one month it was very perfect that we had to send the pictures to them, there were sometimes that we misjudged, for instance I had a client within that month from the first month I thought she was negative but then when I sent the picture to (mentor) she said she is not negative but positive…I didn’t see the pre-cancerous there like the way I was expecting to see but then she was able to let me see it that the person was positive so it was good that they were there to correct us before we got used to the whole thing.” [CHN7]
Adequacy of 3-month training time	“More benefits because at least I had the opportunity to train on cervical cancer and even though I may not know many things about it at least I have gotten the opportunity to know certain things about cervical cancer, I can conduct screening without any support from any facilitator, it’s a big plus for me.” [CHN4]
Peer-to-peer support and feedback	“I call some of my colleagues to help me…I will tell them I got negative so come and check, the person too will come and check, we do collaborative work we don’t do it alone, with the help of our colleagues its ok.” [CHN6]
Perceptions and experiences with using smartphone for VIA screening
Comfort with smartphone imaging	“It was very much comfortable and it was good for the clients because we made the clients aware that…we will take a picture and send it to our (expert) for them to confirm on the results that would come… (and) we made it clear to them that we would take a picture and allow them to see how their cervix is looking like so working with the smart phone has been very very good.” [CHN3]
Dealing with technical challenges for smartphone use	“…at first when we were taking the pictures it was somehow challenging so we just told our facilitator and she told us to zoom and take the picture so when we started doing that it was ok.” [CHN4]
Views on the feasibility of implementation within national programme (CHPS)
Feasibility of continuing programme	“It is possible because even now people are still asking, we give talks on it, and even after this three months we give talks, before then when we started we were finding it difficult to get the clients in doing it but after we’ve got some of them they also sent the information to others” [CHN2]
Nurses’ views and experiences regarding acceptance and comfort of screening by patients
Lack of perceived susceptibility as a challenge to recruitment for screening	“…you are not feeling sick and nothing is wrong with you and somebody just comes and says that it is harmful it can cause this and that while she knows that she is not sick so it wasn’t easy that way so you have to convince and convince before they will accept it that way” [CHN2]
Education to overcome lack of knowledge and fear of screening results	“…it was very difficult and some too were afraid that eeeiii what if I go and they tell me that I have cancer what am I going to do? So that fear was there but the education that we gave them we managed to bring them (in)” [CHN1]
Importance of existing relationships with patients	“It depends on the relationship we have with them, for the churches that we went to, my church per se I have been with them all the time so after I gave them the talk they were like ok and they received the (cervical) screening…” [CHN7]
Minimal privacy concerns	“(patients think) even if someone sees the picture of the cervix they wouldn’t know that it is you” [CHN7]
Technical, logistical and financial challenges during VIA screening
Challenges conducting the procedure screening	“For me (it) would be finding the cervix, some of them immediately you enter you find the cervix some too you suffer, some you have to try, push side and side before you get the cervix” [CHN2]
Logistic challenges conducting the screenings	“…you know the speculum we have different sizes, there was a time I was about to do a screening and I couldn’t get a speculum, all those around were small so I had to go to the other facility and get it from there and explain things to my client and ask her to go home and call her back the next day” [CHN6]
Patients lost to follow-up	“I will say some are very difficult bringing them here, when we even call them they will say I will come but at long last they don’t come.” [CHN1]
Importance of screening as a free service	“…it was free to them but now when we start doing it as part of our duty then it means the speculum and other things they would have to pay for it so it will be a bit of a challenge” [CHN3].
Overall feedback and suggestions to improvement
Pride in ability to provide screenings	“It was rewarding, being able to do it alone and then knowing that I was able to do (it), I was able to identify whether the person was negative or positive before showing it to my supervisor and the supervisor too will check and say its negative, you did a great job, its rewarding.” [CHN6]
Certificate of completion	“…we need to get certificate to prove to people because there are some educated people when they come to do the screening they expect to see something that shows that you are really trained to do the screening on them.” [CHN3]
Suggestion to use mass media for education	“Making the community know about the cervical cancer screen so creating awareness with the information … I think it will help, telling them what it is.” [CHN4] “the education must be mass as in nationwide in the media and all this.” [CHN1]
Suggestion to expand screenings to community-based locations	“…provide us with logistics …like the beds for the cervical cancer screening…all the bed were normal beds so it wouldn’t be easy for our clients to lie down for the procedure…at our weighing centers, where we do our weighing so that we will just clean the place small for privacy and then do the cervical cancer for our nursing mothers because all of them really love to do it…” [CHN3]
Suggestion to add additional chronic disease screenings	“…anytime we go into the community it is health education, health education so the community members are expecting us to do something practical to help them like checking their BP and other things and they are expecting all of these things to be free so actually we also would love to provide them with all these services (blood pressure and checking sugar).” [CHN3]

Numbers indicate the specific nurses.

CHN, community health nurse; CHPS, Community-based Health Planning and Services; VIA, visual inspection with acetic acid.

Overwhelmingly, they agreed with adequacy of 3 months mentorship and emphasised the importance of having a back-up expert to further interpret the images and mentor them after the initial onsite training. Although some CHNs expressed anxiety about performing the screenings, almost all agreed that having expert support made them and the patients feel more confident during the process and that the expert reviewer’s responsiveness and individualised support improved their competency. Most CHNs elaborated that seeing positive VIA cases was very important and was integral in learning, but all agreed that negative cases were easier. CHNs also agreed that almost all patients understood when they were told to wait for the expert to confirm a potentially positive or negative case during mentorship period, as feedback was provided by the mentor either immediately or within 24 hours, depending on availability of the mentor. Another helpful aspect of the 3-month training period was peer-to-peer support from colleagues for diagnostic input.

Overall, the CHNs found smartphones easy to use for cervicography and sending photos to the mentor, and experienced few logistical issues (such as issues with SIM cards, texting or network). Electricity outage was an occasional barrier which was largely addressable. Although some nurses had some initial difficulty with taking quality photos, the expert support helped to improve quality of images over time. CHNs elaborated that describing the process to patients and showing them their cervical pictures made them more assured and comfortable with screening. Almost all CHNs felt that smartphone-based cervicography VIA is very easy to integrate into the screening process. Overall, nurses were proud of their work. They suggested a peer support network to discuss pictures and cases. Nurses overwhelmingly mentioned that they would appreciate having a certificate of training completion to mark their achievement and competency.

CHNs believed that more and more people will come to get screened because it has already received attention, and both information and acceptability seem to be increasing in the community. Nurses believed that they are the most appropriate personnel to administer this service, especially considering the sensitive nature of the procedure, and because of the familiarity and trust they have garnered within communities. CHNs acknowledged that potential screening cost would be a barrier, and that assuring the screening was free of charge was important. They reported a general lack of knowledge of cervical cancer and screening as challenges to attracting patients. CHNs reported that some patients believed that screenings were unnecessary because they were asymptomatic. Other barriers to convincing patients included anticipated pain during the procedure, potential cost and fear of knowing about a positive screening result. CHNs reported that educating patients on cervical cancer and screening, and its importance in preventing cancer helped overcome these barriers. CHNs also relied on their existing trusting relationships with patients to encourage screening. They felt that most patients accepted undressing for the exam, with some patients comparing the nudity to the experience of childbirth. CHNs reported that their patients had minimal privacy concerns with having their cervix photographed, since the picture was anonymous and viewed only by the patient, nurse and the expert reviewer.

Overwhelmingly, nurses did not face any major technical challenges in performing VIA. A minority mentioned that it was difficult at times, but manageable, to find the actual cervix. Logistical challenges included the cost of transportation, both for patients and CHNs; at times, securing a steady supply of equipment and resources; the quality of equipment including exam beds and the relatively small size of the screening area which posed minor challenges to maintaining patient privacy. Commonly used medical exam beds were available in all facilities or mobile units. Lighting was supported by stationery medical exam lamps. Bedsheets, gloves, and other supplies and materials for screening were all part of usual supplies in the clinics/health facilities and used based on Ghana’s Ministry of Health recommendations for infection control and OBGYN exam. Smartphones had flashlights and were used for photography in a protocolised fashion developed for this study. None of the CHNs perceived transport time as a barrier for patients; however, the transportation cost was among the most common reasons women missed screening appointments. Almost all CHNs agreed that paying for transportation would improve the screening process. CHNs suggested ways to improve awareness and education by making announcements through radio, TV, newspapers and social media. To improve patient screening participation, they suggested going door-to-door, and reaching out to local churches. They also indicated the need for both nationwide education and community mobilisation. Other improvements of the experience included access to equipment for screening such as better quality, sturdier exam beds; offering screenings at opportune times like when women are at health centres for other reasons, or screening in the community. They suggested expanding screening services to include breast cancer, diabetes and blood sugar levels, hepatitis B and hypertension. Several mentioned a recent reduction in previous services due to a lack of funding, emphasising the importance of keeping these services free to the public.

Perceptions and experiences of the nurse supervisor and expert reviewer

Both the supervisor and expert reviewer generally agreed with CHNs regarding the appropriateness of the training and its incorporation and adequacy of both theoretical and practical trainings. They added the need to reduce the size of the training groups in order to provide more personalised attention to each training during the initial onsite sessions (groups of 6–7 rather than 15–20). This would also allow the trainer to identify and provide targeted attention to different trainees. The expert reviewer did not cite any logistical challenges with receiving and sending images and mentoring and providing feedback. Actually, the reviewer spent some time helping a few CHNs improve the quality of their photos but she did not find this a significant challenge. She found the process very rewarding and elaborated on the importance of providing 3-month remote mentorship to help advance and further polish CHNs’ diagnostic skills as a more practical training that complemented classroom exposure. This in turn improved the reviewer confidence regarding the competence of CHNs and screening quality.

Perception and experiences of patients

Largely, both patients who were screened negative and those who were screened positive and received cryotherapy shared similar perceptions and experiences. Quotes from patients exemplifying each theme are presented in table 2. None of the patients, including the cryotherapy patients, had ever been screened before, and most had no prior knowledge of cancer or screening. For the few with some prior knowledge, past exposure included TV or radio, or informal information from nurses when visiting health facilities on unrelated occasions. Only a small number of patients understood the concept of screening, prevention and the importance of knowing ones’ disease status. Many expressed misconceptions, either their own or beliefs they had heard from others. One patient elaborated on misconceptions, sharing her belief that cervical cancer is caused by inserting things into the vagina. Other misconceptions about screening included worrying about being ‘clean’ or ‘neat’ enough to be screened or that nurses would put their hands inside patients. Most patients did not discuss the screening with anyone, and decided to participate in the screening on their own. Only a few asked partners for approval and the majority reported that their husbands or partners supported their decision. They elaborated that some men did not think the screening was relevant to them; however, most, but not all, men in the community support screening. A few said that some men had issues with it but generally if women decided to get screened, then they could find a way without their partner’s approval.

Table 2

Patient quotes on their perceptions and experiences, smartphone-based VIA cervical cancer screening, Accra, Ghana, 2015

Theme	Quote
Knowledge and attitude regarding cancer and screening and health decision-making process
Lack of prior knowledge	“…when I heard about the disease at that time I did not take it seriously because I did not really understand it very well but when the nurse came to explain then I knew how important it was to go for the screening.” [SP6] Even though I heard about it I was not scared of it because when I started life as a young lady I did not insert those things that people put into their private part and I did not do those rough things. So even though I heard about it I never went to check or screen.” [SP2]
Low education levels	“Where I live, most of the people there have low educational background so I think they don’t (know) much about health so maybe for them if they experience any problem in their private part they can grind pepper and insert it there and (for) such people it is not easy to convince them to come for this screening.” [SP5]
Misperceptions about screening	“In fact it was not easy convincing them (other women) because some of them were saying that when you go they will be inserting hands in their vagina and others were saying all sorts of things so I told them that when I went I did not experience that.” [SP2] “she (another woman in community) was saying if she comes they will say this today and that tomorrow and she does not know what they will be inserting into her” [SP5]
Support of partners for screening	“Well, I explained to the man I live with about the screening but I had decided to do the screening already so when I explained it to him too he said it was good so I should come and do it so that if they give medicine I can also get some.” [SP4]
Support of men in the community for screenings	“…the day the nurse was telling me about the screening, there was a man there and he was even more interested in listening to what the nurse had to say and he even said he will tell his wife and sister to go for the screening” [SP6]
Appreciation for effort of CHNs	“Well she educated me, first of all she explained to me what cervical (cancer) is and how it is contracted…and she explained to me how everything is going inside. I was asking a lot of questions so she kept explaining to me.” [SP3]
Photos as an educational tool	“…When they came to my workplace they showed the picture to us, I mean to the nursing mothers as well telling them how the disease looks like, so it was the pictures that I saw that got me scared so I decided to come for the screening.” [SP7]
Shyness as barrier to screening	:“…they (other women) support it but it is just that some of them are shy.” [SP13]
Patients’ expectations and experiences of screening and logistical barriers
Importance for preventing cancer fatality	“…you can see that it is dangerous, I saw the pictures. If you have this infection (disease) how will you know, so if they are able to check and see if you have the disease and they cure it for you then it is good and if they check and they see that you don’t have it then you can protect yourself. So it will be good if it is detected early rather than you will wait till the disease becomes worse when nothing can be done about it.” [SP2] “…even though the time they did the screening I had to go to work I decided to use that time to come…because I wanted to know if I had the cancer or not.” [SP12]
Trust for CHNs	“I did not have any expectations and I also trust the nurse who came to inform me about the screening.” [SP1].
Screening was less complex than expected	“I thought that when I come they were going to do an operation or something of that sort before they can see it but when I came they said it was not like that, they made me lie down and they put under me and took a picture of it and showed it to me” [SP15] “as for me when they say they want to look at the mouth of the womb I think (hahahahah) they will remove it and wash and then they can see if it has a disease or not so that is what I think…” [SP2].
Minor discomfort	“I was ok I did not experience any discomfort, it was just a little bit painful but later it was ok.” [SP15]
No cost as a motivator	“…when she said the screening is free I decided to come” [SP2]
Importance of improving awareness	“I think that the announcement and awareness should be more, because the nursing mothers they came to speak to, at my workplace, are just a few women so they should speak to a lot of people so that they can also come for the screening.” [SP11]
Cervicography and smartphone-based VIA, and cryotherapy
Smartphone as a reassurance	“…if she does not take a picture of it how would she know if I have the disease or not and how will she be able to show it to me? Because I have to see it myself, if I don’t see it I may say she is telling lies because I have been to a number of places and they say I don’t have any problem but I don’t see it.” [SP15]
Trust of providers and professionalism	“I was ok with it because she has to do it and that is her work, you are a woman when you go for consultation you need to be free and let the person do her work so that she will know what is happening to you so I wasn’t having any problem with it.” [SP3]
Experience of cryotherapy	“I was very comfortable.” [SP5] “it was ok, the time, she came on Saturday it was ok because if she had come within the week I would not have been able to come but the time she came it was favorable.”[SP1].

SP indicates patients; numbers indicate the specific patients.

CHN, community health nurse; VIA, visual inspection with acetic acid.

Most patients appreciated cervical photography and wanted to see the picture of their own cervix. For many, the photos helped answer their questions and, for some, it reassured them about the procedure. Some women wanted to take their cervical images to show to their partners or keep as a record. Therefore, if and when patients requested to have their cervical digital images and had a smartphone, providers allow them to take the picture or transferred images securely to the patient’s smartphone. These images were all deidentified and anonymised. Printing images was not possible or provided. Due to the anonymity, the majority were comfortable with having pictures taken. Only one patient had questions and requested reassurance about potential sharing of her images on the internet. Most others trusted the CHNs and understood and agreed with the process of smartphone-based VIA. Patients were generally appreciative of CHNs’ persistence in educating them and addressing misunderstandings and misconceptions through describing the screening process, cancer detection and treatment, and relaying the importance of prevention. Some patients mentioned that the CHNs showing pictures of cancerous lesions and describing risk factors for cervical cancer was often effective in encouraging screening. The majority of patients reported little or no stigma from relatives or community members for getting screened. Although most patients stated that a large number of women in the community support screenings, some alluded that barriers included embarrassment or shyness and low health literacy. While some women discussed misconceptions in their community regarding the procedure itself, most clients were optimistic that more men and women would support the screening if they were educated more about the procedure.

Majority of clients had no specific expectations of the screening prior to their procedure, and they largely trusted the CHNs as health professionals. Overall, clients found it easier, shorter, and less painful than expected. Some expected a much more complicated or painful procedure such as that the uterus to be taken out and washed and inspected. Although a few experienced initial discomfort, it was often relatively minor and short-lived. None of the clients had any significant logistical barriers during the screening. A few mentioned issues with transport cost, the majority thought that screening time was reasonable, and appreciated the screening being free. Some clients skipped work to be screened. Majority of clients were happy with the screening, and did not offer any specific recommendations for improvement. Some clients inquired about and suggested providing breast cancer screening. Most of them acknowledged it was important to have more announcements and awareness, in one case suggesting that nurses go house to house in order to educate people. Individual women who received cryotherapy after screening positive through VIA cited positive experiences with the process and did not report any specific privacy issues, or additional pain or discomfort or logistical barriers.

Discussion

Cervical cancer screening using VIA and smartphone was highly accepted by the clients, none of whom had prior screening, and by CHNs who were performing this screening for the first time. Neither group cited significant barriers to receiving or performing VIA at CHCs, the incorporation of smartphone imaging, the process of mentorship via text messaging, privacy or confidentiality, or other issues with stigma or logistical barriers. Some barriers to screening cited by both clients and CHNs closely resembled those of patients in more developed regions, such as fear, embarrassment or lack of knowledge or awareness.40 The training, including initial on-site and subsequent mentorship using smartphone imaging and texting, was very well received. The 3-month mentorship was an important and effective complementary training to further develop and enhance the needed competencies. Both CHNs and their trainer and supervisor regarded the didactic and practical components of the onsite training as interrelated and vital to its effectiveness. CHNs found the training to be empowering and welcomed the opportunity to learn a new skill, and the opportunity to provide additional services to women in their catchment areas. The importance, value and synergistic effect of having continuous diagnostic support in the first 3 months was essential. Smartphone-based imaging provided opportunities to see and discuss cases that they did not see during their initial training such as identifying more positive or complicated cases,36–38 and provided the opportunity to revisit images and discuss difficult cases with colleagues, all of which facilitated learning. Discussing images with the mentor further reinforced clients’ trust, and clients overwhelmingly accepted smartphone-based imaging, had no significant privacy issues and felt more reassured of the procedure.

The possibility to discuss and learn from their own experience, and individualised support and mentorship during this 3-month period improved competency and confidence in managing their clients. Adult learning theory describes the main mechanisms by which adults learn skills when they relate to daily activities and working responsibilities, learning is hands-on and takes place over time, there are peer-to-peer learning opportunities and there are possibilities to ask for and receive targeted feedback related to their cases/questions as opposed to learning in classroom settings.41 42 The use of smartphones provided a likely unmatched opportunity to connect new providers to peers and senior providers, and improved access to case-by-case learning. This important mentorship component has been largely missing from widespread standard VIA trainings.43 There were additional important and unanticipated benefits of photography including using photos to better communicate with clients about the procedure and gain more trust, further provide targeted health education regarding sexual and reproductive health, and implement some form of quality control. The ease of using smartphones and the lack of serious logistical barriers were important findings on feasibility from the perspective of all stakeholders, and highlight the potential of smartphones and mentorship in improving quality, accuracy and efficacy of VIA.36–38 Smartphone imaging could be used to further create a peer-support network such as a virtual journal club to reinforce peer learning and support, which could be used as a measure for quality control. There is also the potential for better effectiveness of VIA strategies through improving adherence and acceptance by clients due to better understanding of the procedure, addressing misconceptions among clients and their partners and possibility for medical record keeping by clients.

The majority of clients had no, or very little, prior knowledge about cervical cancer or screening. The availability of and persistence of CHNs, from their own communities, in providing basic education about the disease, screening and addressing existing misconceptions were essential in ultimately encouraging women to get screened. Although there were important misconceptions, fear of screening or its results, and some stigma, clients were receptive and communicated the overall benefits for themselves and others. Women largely seemed to express autonomy about decisions regarding screening and they were able to manage any potential opposition by their partners without assistance. Negative views and stigma on the part of others (men or women) were not uncommon but were generally not significant barriers. Despite important misinformation regarding the causes of cancer and side effects of the screening, the majority felt that screening strategies were acceptable.

CHNs were generally satisfied with conducting the screening, felt empowered and gained more confidence in their capacities, and saw their efforts as a meaningful component of their jobs. Nurses were keen to be certified and considered that an important factor for career development but also to further gain confidence and trust from clients. All CHNs who participated in this project were women and had experience providing basic maternal and child care and health education to residents of their respective catchment areas. Strong prior relationships with clients and perhaps their gender seemed to foster an ease of the process and better convince clients for screening, and helped address issues of privacy and sensitivity. Equally important compared with knowledge and attitude is trust of providers, which could ultimately encourage clients to make the decision regarding seeking care especially screening for asymptomatic conditions.5 CHNs were able to leverage their existing relationships and their own persistency to address a significant lack of knowledge regarding cancer and screening. Women had other barriers and competing priorities such as cost of transport, time constraints and childcare responsibilities. These were often locally managed by women and CHNs working together, and providing some transportation support to clinics for the procedure. Other logistical barriers such as screening supplies were generally managed by existing resources at the centres. Having screening free of charge was an important factor and needs to be factored in for implementation strategies.

Clients and CHNs had some suggestions to improve the experience including providing more and better-quality facilities and mobile clinics at churches or in the community to bypass transport to clinics. However, this needs to be balanced to ensure that quality is not impacted by mobile units. CHNs generally felt positively regarding the feasibility of incorporating VIA screening into existing services as a long-term strategy. Clients requested additional screening programmes such as breast cancer, which was also suggested (with hypertension and diabetes) and deemed feasible by CHNs. Although CHNs felt that they were quite capable and proud of providing the screening to women in their community, they expressed some scepticism regarding funding for maintaining screening programmes. At the national level, priority setting should include a balance between the cost and outcomes and competing programmes. All these findings may have implications for VIA screening strategies and their implementation into regular health system services at the primary care level as opposed to vertical or targeted services at tertiary care centres or flash mass screening programmes.

Limitations

Our study was not without limitations. Although the CHPS programme in Ghana was based on previous service delivery models from rural areas, the two pilot study areas were part of an expansion of the programme, in which the model was adapted to peri-urban and urban areas. Thus, findings may not be generalisable to rural areas, particularly given differences by region in access to social and healthcare resources. As this evaluation was a pilot study to evaluate the effectiveness of using mHealth strategies to extend and improve training in VIA to CHNs, additional challenges may be associated with scaling up such an intervention to larger areas. Additionally, there is a possibility of bias towards acceptability of the intervention. However, we included all CHNs in two facilities rather than relying on a self-selected sample, and patients were recruited using criteria sampling. We also included all clients who received cryotherapy to explore their views towards the screening and treatment strategies. Finally, this qualitative study by its nature only generates hypotheses which need to be further tested quantitatively for validity and generalisability. Nevertheless, we were able to observe existing community perceptions through the lens of participating patients and nurses as they were also asked and subsequently elaborated on views and perceptions from their own community different or consistent with that of their own.

Conclusions

Our findings indicate overall acceptability and ease of implementing smartphone-based imaging for VIA and training and mentorship of mid-level health personnel for cervical cancer screening. Anticipated barriers, such as concerns for privacy and confidentiality, knowledge and attitude gaps, fears and misconceptions and logistical challenges were largely minimal or manageable. The use of smartphone imaging provided unexpected benefit as an educational tool to increase patients’ adherence and improved VIA training for CHNs by providing mentorship and peer-to-peer education opportunities. Overall, and especially for more remote areas, there are important promises for quality improvement and effectiveness of smartphone-based VIA screening and its implementation. Further and complementary context-based implementation research is needed to appropriately test smartphone-based imaging for scale-up efforts and addressing the cervical cancer burden in LMICs.