Literature DB >> 3131427

A new murine Ig VH gene family.

R Kofler1.   

Abstract

A novel murine VH gene family, termed VH10, has been found and characterized. Based on RFLP analysis, this family exhibits extensive polymorphism among inbred strains of mice and encompasses two to five members, depending on the Igh haplotype. Analyses of recombinant inbred strains suggest a map position of this family 5' to the 7183 and Q52 VH gene families. A VH10 gene has been found to encode anti-DNA autoantibodies from lupus mice; another one may be a pseudogene.

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Year:  1988        PMID: 3131427

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  17 in total

1.  Normal serum immunoglobulins participate in the selection of peripheral B-cell repertoires.

Authors:  A A Freitas; A C Viale; A Sundblad; C Heusser; A Coutinho
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-01       Impact factor: 11.205

2.  Hamster cDNA homologs to the mouse immunoglobulin IgG2 constant and Igh-VH10 genes.

Authors:  M Collins; M J Whitters
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

Review 3.  B and T cell antigen receptor repertoires in lupus/arthritis murine models.

Authors:  A N Theofilopoulos; P A Singer; R Kofler; D H Kono; M A Duchosal; R S Balderas
Journal:  Springer Semin Immunopathol       Date:  1989

4.  Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice.

Authors:  R Kofler; R Strohal; R S Balderas; M E Johnson; D J Noonan; M A Duchosal; F J Dixon; A N Theofilopoulos
Journal:  J Clin Invest       Date:  1988-09       Impact factor: 14.808

5.  Evolution of the immunoglobulin heavy chain variable region (Igh-V) locus in the genus Mus.

Authors:  A Tutter; R Riblet
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

6.  Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus.

Authors:  B P Tsao; F M Ebling; C Roman; N Panosian-Sahakian; K Calame; B H Hahn
Journal:  J Clin Invest       Date:  1990-02       Impact factor: 14.808

7.  Deletion mapping of the mouse ornithine decarboxylase-related locus Odc-rs8 within Igh-V.

Authors:  B A Richards-Smith; P H Brodeur; R W Elliott
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

8.  Blot-sequencing of antibodies: application to analysis of V gene usage among anti-steroid monoclonal antibodies.

Authors:  M J Taussig; P R Symington; M Woods; M J Sims; D Beale; A S Humphreys; A J Northrop; P J Barker; N S Huskisson; J Coley
Journal:  Immunology       Date:  1991-04       Impact factor: 7.397

9.  Antibody recognition of a neutralization epitope on the major outer membrane protein of Chlamydia trachomatis.

Authors:  G Zhong; J Berry; R C Brunham
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

10.  Molecular cloning of the primary IgH repertoire: a quantitative analysis of VH gene usage in adult mice.

Authors:  K M Sheehan; P H Brodeur
Journal:  EMBO J       Date:  1989-08       Impact factor: 11.598

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