OBJECTIVES: Sociocultural factors have been hypothesized as important drivers of inappropriate antibiotic prescribing in European ambulatory care. This study sought to assess whether they can also explain the reported variation in broad-spectrum antibiotic (Br-Ab) use among EU/European Economic Area (EEA) countries. METHODS: Correlation and regression analysis were performed, using the bootstrap method, between Br-Ab ratios reported from 28 EU countries by the ECDC, and national Hofstede cultural dimensions and control of corruption (CoC) scores. RESULTS: Significant bootstrapping correlation coefficients were identified between Br-Ab ratios and the dimension of uncertainty avoidance (UAI) as well as CoC. However, following both bootstrapping multiple regression and generalized linear modelling, only UAI was retained as the sole predictor. A logarithmic model explained 58.6% of the variation in European Br-Ab variability solely using national UAI scores (P < 0.001). CONCLUSIONS: Br-Ab prescribing appears to be driven by the level of UAI within the country. Any interventions aimed at reducing Br-Ab in high-consuming EU/EEA countries need to address this cultural perception to maximize their chances of success.
OBJECTIVES: Sociocultural factors have been hypothesized as important drivers of inappropriate antibiotic prescribing in European ambulatory care. This study sought to assess whether they can also explain the reported variation in broad-spectrum antibiotic (Br-Ab) use among EU/European Economic Area (EEA) countries. METHODS: Correlation and regression analysis were performed, using the bootstrap method, between Br-Ab ratios reported from 28 EU countries by the ECDC, and national Hofstede cultural dimensions and control of corruption (CoC) scores. RESULTS: Significant bootstrapping correlation coefficients were identified between Br-Ab ratios and the dimension of uncertainty avoidance (UAI) as well as CoC. However, following both bootstrapping multiple regression and generalized linear modelling, only UAI was retained as the sole predictor. A logarithmic model explained 58.6% of the variation in European Br-Ab variability solely using national UAI scores (P < 0.001). CONCLUSIONS:Br-Ab prescribing appears to be driven by the level of UAI within the country. Any interventions aimed at reducing Br-Ab in high-consuming EU/EEA countries need to address this cultural perception to maximize their chances of success.
Authors: Erika A Saliba-Gustafsson; Anna Nyberg; Michael A Borg; Senia Rosales-Klintz; Cecilia Stålsby Lundborg Journal: PLoS One Date: 2021-02-11 Impact factor: 3.240
Authors: Alike W van der Velden; Alma C van de Pol; Emily Bongard; Daniela Cianci; Rune Aabenhus; Anca Balan; Femke Böhmer; Valerija Bralić Lang; Pascale Bruno; Slawomir Chlabicz; Samuel Coenen; Annelies Colliers; Ana García-Sangenís; Hrachuhi Ghazaryan; Maciej Godycki-Ćwirko; Siri Jensen; Christos Lionis; Sanne R van der Linde; Lile Malania; Jozsef Pauer; Angela Tomacinschii; Akke Vellinga; Ihor Zastavnyy; Susanne Emmerich; Adam Zerda; Theo J Verheij; Herman Goossens; Christopher C Butler Journal: BJGP Open Date: 2022-08-30